- Most women have estrogen dominance (too much estrogen relative to progesterone), which drives weight gain around your cycle, but taking progesterone cream incorrectly or at too high a dose can actually cause weight gain instead of fixing it.
- Use bioidentical progesterone cream, not synthetic progestins or oral forms, applied during only the last 2 weeks of your cycle at 20-40mg daily. Taking it correctly prevents side effects like water retention, bloating, and paradoxical weight gain.
- Progesterone works best if you have low serum progesterone levels, are menopausal, or have hypothyroidism or insulin resistance creating estrogen dominance. Check your levels first before supplementing.
- Your thyroid and stress hormones affect progesterone production, so treating hypothyroidism and supporting your adrenals will improve your natural progesterone levels without needing supplementation.
- High cortisol from chronic stress initially raises progesterone but then depletes it over time, which is why stress management is critical for hormone balance and weight loss.
When you think of progesterone most of us are conditioned to think that it causes weight loss.
But the truth is that progesterone can cause both weight loss and weight gain, depending on the situation of who is using it.
Not only that but how you take progesterone and at what dose may determine if it helps with weight loss or weight gain.
Progesterone and Your Weight
Healthy and normal levels of estrogen and progesterone are required for a woman to maintain a normal weight.
The problem comes from understanding this balance and how to achieve it using supplements and creams.
You can think of estrogens (including estrone, estradiol, and estriol) as growth hormones.
Estrogens make your cells bigger, whether that be your fat cells, uterine cells, or breast tissue.
Progesterone, on the other hand, helps counteract these effects of estrogen (1).
In this way, progesterone is a natural way that your body balances estrogen levels.
So even though most women gain some weight during their menstrual cycle, that weight is lost once your hormones even themselves out.
So how does weight fit into this picture?
What I’ve just described is how the system is SUPPOSED to work, but that doesn’t mean that it works this way in every person.
Most women (at least in the United States) have trouble with too LITTLE progesterone and too MUCH estrogen.
This results in an imbalance known as Estrogen dominance, meaning you have too much estrogen relative to progesterone.
Most women know if they fall into this category because they present with symptoms like these:
- History of endometriosis
- History of fibrocystic breast disease
- History of PMS or PMDD
- Severe depression or anxiety around menstruation
- Perpetual weight gain surrounding menstruation
- Hormonal acne that changes with your menstrual cycle
- History of migraines related to your hormones
- Breast tenderness, heavy menstrual cramps, or mood swings
If you fall into any of the categories above then chances are high that you do indeed have an imbalance of estrogen to progesterone in your body.
You can find more information about how to treat these symptoms using supplements in this post.
Does that mean that you should automatically take progesterone to balance the high estrogen?
Not necessarily, and this is what gets people into trouble.
The answer to high estrogen is not to dramatically increase your progesterone level.
In fact, taking progesterone if you have normal levels of progesterone, to begin with, is what causes weight gain in many people.
Another important factor has to do with how you take progesterone and how MUCH you take (more on this below).
You have to consider that each person
Most of the weight gain from progesterone comes from excessive or high doses.
But how do you know if you are getting too much progesterone?
Follow the symptoms!
Symptoms of excess progesterone in your body:
- Weight fluctuations(usually mild weight gain of 5-10 pounds)
- Drowsiness
- Depressed feeling but not overt depression
- Slight dizziness
- Waking up groggy or “on edge”
- Bloating
- Sense of physical instability
- Feeling of a spinning sensation
- Discomfort or pain in the legs
- Water retention
- Anxiety or just feeling “tense”
- Changes to libido(usually decreased sex drive)
- Not feeling like yourself
These symptoms indicate that you have TOO much progesterone in your body, and if you are taking progesterone and experiencing these symptoms then chances are you might also be gaining weight.
This weight gain may stem from the dose you are taking, HOW you are taking the medication or the frequency with which you are taking progesterone.
It doesn’t necessarily mean that you need to stop taking the medication ASAP.
Let’s take a closer look at how to make sure you are taking progesterone correctly:
How you take progesterone matters
Remember there are really only two ways you should be using progesterone:
- Bioidentical progesterone cream
- Bioidentical oral progesterone (Prometrium)
You should NOT confuse these types of progesterone with synthetic or fake pharmaceutical forms of progesterone that most physicians prescribe.
Pharmaceutical companies don’t like to make bioidentical hormones because they can’t patent the medication and therefore they can’t make very much money.
Instead, they slightly alter the progesterone molecule and brand it with a new name.
But you want to stay away from these types of progesterones (called progestins or progestagens) because they are NOT metabolized in the same way as normal progesterone.
These synthetic and fake types of progesterones are responsible for a lot of weight gain that many people experience as well.
In fact, some studies have shown that some women may gain several pounds (2) while taking progestin-only birth control medications.
So we know that taking fake and synthetic progesterone is out of the question, but what about taking bioidentical progesterone pills? Is that okay?
Whenever possible it’s always best to mimic nature when you are replacing hormones.
For progesterone that means the following:
- Making sure that any progesterone you take bypasses the first metabolism from the liver (normally, progesterone is secreted straight into your bloodstream) -> this means a preference for creams/gels instead of oral progesterone
- Taking progesterone when it would naturally be high during the menstrual cycle (during the last 2 weeks or the luteal phase)
- Avoiding synthetic formulations of progesterone (use only bioidentical forms)
- Taking only enough progesterone for YOUR body (the dose that each person needs will be different)
If you aren’t following these guidelines, even if you are taking bioidentical progesterone, your dose may be simply too high or you may be taking it the wrong way.
It’s important to discuss these nuances because it might just be that progesterone isn’t your problem, but it’s more about how you are taking it.
We will go over in detail how to use progesterone below, but for now, let’s talk about who should seriously consider using progesterone for weight loss.
Who should use Progesterone for Weight Loss:
#1. Patients with low serum progesterone levels
This should go without saying, but if you have LOW progesterone then you are a great candidate for progesterone replacement therapy.
As long as you use bioidentical progesterone therapy with a transdermal application, at the right dose, there is a very low chance that you will have negative consequences such as weight gain.
But how do you know if you have low progesterone?
It’s actually quite easy to test your blood levels of progesterone. All you need to do is ask your doctor for a “serum progesterone” blood test.
Make sure you get tested on days 19-21 of your menstrual cycle (assuming a 28-day cycle).
If your serum progesterone is low when you test on these days then you are likely not creating ENOUGH progesterone or you are having anovulatory cycles.
This is also where things start to get interesting:
Progesterone levels obviously fall off dramatically during menopause (after ovulation ceases) but what you might not have realized is that progesterone naturally reduces around age 35 as well.
Both estrogen and progesterone decline around this time, but progesterone declines more rapidly.
This process leaves a relatively high concentration of estrogen relative to progesterone and this is why many women begin to suffer from the symptoms of estrogen dominance.
Starting at age 35 you may consider using progesterone IF your levels are low.
#2. Women who are menopausal
The second reason to use progesterone is due to a deficiency from menopause.
Once a woman hits menopause (whether that be from chemicals, hysterectomy, or the course of time) she is no longer ovulating.
Because ovulation is the biggest source of progesterone in women, the reduction of ovulation almost always results in VERY low progesterone levels.
It’s worth pointing out here that you can hit menopause early if you undergo removal of your ovaries due to surgery, or if you take certain medications (like those for breast cancer).
Both of these conditions create an early menopause-like syndrome which results in near zero progesterone levels.
The problem with menopause is that while progesterone levels drop to nearly zero, estrogen doesn’t always follow that trend.
Why?
Because your body can take androgens (DHEA and testosterone) and turn those into extra estrogen through your fat cells.
This process is known as aromatization (3) and it occurs in both men and women.
This creates a very interesting and troublesome scenario in many menopausal women:
If they have extra fat on their body they may create much more estrogen than normal while they have virtually zero progesterone.
This may, in part, help explain why menopausal women tend to gain weight (on average about 15 pounds).
The bottom line?
If you are menopausal you can almost guarantee that your progesterone level is very low and replacing those low levels may help with weight loss.
#3. Women with Estrogen Dominance should consider it
We’ve been talking about this idea of having too much estrogen during menopause but what about other women? Do they deal with the same issue?
And the answer is yes.
The following conditions may result in excess estrogen AND low progesterone levels:
- PCOS or being on the PCOS spectrum
- Insulin resistance, diabetes (either type I or type II), or issues with blood sugar
- Hypothyroidism
- Obesity or weight gain from any cause
- Eating disorders, binge eating, emotional eating, etc.
- High stress or a history of adrenal problems
- Exposure to xenoestrogens or endocrine-disrupting chemicals (4)
These conditions result in a scenario where estrogen levels remain high while progesterone levels may be artificially lower than normal.
Women who fall into any of these categories may benefit from using progesterone ASSUMING their levels are low.
You might also notice that many of these conditions are associated with weight gain in some form.
The use of progesterone in this setting may ultimately help with weight loss, but don’t count on it.
Also, do remember to check your serum progesterone level prior to supplementing as sometimes serum progesterone levels (even in these conditions) may be normal or high.
It’s possible to have more than 1 hormonal abnormality going on at once.
#4. Women with hypothyroidism should consider using Progesterone Cream
Next on the list is worth mentioning a second time:
Women suffering from hypothyroidism.
Why?
First of all, hypothyroidism is very common, and worse than that it is misdiagnosed by many physicians.
This creates a scenario where many women are walking around with hypothyroidism and low progesterone without even knowing it.
In addition, thyroid hormone plays a special role in helping maintain normal progesterone levels and normal ovulation.
Low thyroid hormone results in decreased ovulation and therefore decreased progesterone.
This relationship helps explain why women with hypothyroidism suffer from infertility and difficulty maintaining pregnancy until they are treated.
You can see the complete list of thyroid symptoms in this post where you can also learn how to be properly tested.
#5. Women with severe fatigue or adrenal fatigue
Lastly, there is a strong connection between cortisol, stress, and progesterone.
The unifying theme here is that these hormones all interact with one another and therefore must ALL be considered if you have a hormonal imbalance in your body.
The connection between stress and progesterone is sinister because it is often ignored or missed.
High levels of stress lead to high levels of cortisol.
As you can see from the diagram below, cortisol has an impact on multiple systems in your body (pretty much every cell):
This impact extends to your sex hormones like progesterone and estrogen.
Higher cortisol levels initially may stimulate high progesterone levels (leading to weight gain), and if the stress is maintained it may ultimately lead to low progesterone levels (5).
You’ve seen this relationship at play if you’ve ever had your cycle delayed or altered due to high-stress levels (relationship problems, finals at school, etc.).ย
The point is to make sure you address your adrenals with certain supplements which can dramatically improve your progesterone levels.
You can find out how to treat your adrenals and lower stress levels in this guide.
Cream vs Oral Progesterone (Prometrium)
If you decide to use progesterone (because you fall into the categories listed above) there are 2 options for you that are both bioidentical.
Your default should be to use the cream FIRST and then do a trial of the oral progesterone if the cream fails (some people just don’t absorb as well as others).
Who should use progesterone cream:
- Those who have not tried progesterone previously
- Those who do not tolerate the cream or have a hard time finding their optimal dose
- Those who can’t find a physician willing to prescribe them oral progesterone
- *Note: Progesterone cream can be purchased over the counter without a prescription but oral progesterone requires a prescription.
How to Supplement with Bioidentical Progesterone
- If menstruating: Use 20-40mg per day on days 14-28 of your cycle (the latter half of the month)
- If in menopause: you can use 20-40mg per day either 6 days per week (with rest on the 7th) or 26-28 days per month (with 1-3 days off per month)
- Make sure to monitor your symptoms while using and discontinue use if you experience any negative side effects
- Discuss the use of bioidentical hormones with your physician
Get bioidentical progesterone here.
Your next option is to use oral progesterone which comes as the brand name Prometrium.
The problem with using oral progesterone is that it is not metabolized the same way that transdermal progesterone cream is.
The metabolism of oral progesterone leads to high levels of pregnanediol which is not normal for the body.
Having said that some women do benefit tremendously from oral formulations of progesterone.
Who should use oral progesterone?
- Those who have failed progesterone cream
- Those who need very small doses of progesterone
- Women who forget to use progesterone cream daily
- Women who are also using multiple other transdermal hormones
- Women who suffer from insomnia
Remember, if you need to use oral progesterone make sure you get bioidentical progesterone (Prometrium) and NOT a synthetic progesterone.
Back to you
Progesterone, depending on how it is used, can cause either weight loss or weight gain.
The problem with using progesterone is that you must be using the right type, the right dose, and use it in the right way (preference on a cream or transdermal application).
If you follow these instructions and only use them when it is necessary, you will benefit tremendously from their use.
Now I want to hear from you:
Are you using progesterone? Is it helping you with weight loss?
Has it caused weight gain?
Share your story and leave your comments below!
Scientific References
#1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964851/
#2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951762/
#3. https://www.ncbi.nlm.nih.gov/pubmed/234975
#4. https://www.ncbi.nlm.nih.gov/pubmed/18942551
#5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288428/
Dr. Childs, you discussed balance between the hormones. What should the ratio of estrogen to progesterone be in post menopausal women?
Hi Cleo,
For menopausal women the ratio is less important than it is for menstruating women. You can generally base dosing off of symptoms (but you should still evaluate labs during this process).
Thanks for the reply.
To respond to your post, I am one of those who suffers immediate weight gain taking progesterone — bioidentical compounded or micronized pills, creams, other delivery methods, even small doses. Sublingual is the only method I have not tried. Aside from the ideals of “balance,” I feel better not taking it at all.
It’s certainly not necessary if you don’t tolerate it, so I think that’s a reasonable approach for now.
Really? That’s all there is to it? Just stop? What if the lab results show that progesterone levels are very low? Just curious as to how they will get balanced on their own.
Hi Dr. Childs,
Any insight as to how Progesterone supplementation in the form of Prometrium can cause severe acne on face and neck? I have low progesterone with estrogen dominance and have taken both Compounded pill, cream, and Prometrium. I normally do not have acne. I also have Hashimoto’s and am on Nature-Throid . I just ceased taking the Prometrium and the acne stopped. My doctor is ordering me Compounded Progesterone as he said it has a yam base vs the peanut oil of Prometrium. Just curious if you have an idea why it would cause onset of acne. Thanks!
Hi Antionette,
It’s well known that progesterone can cause and worsen acne but I’m not necessarily sure as to why it occurs.
I’ve written about potential causes in this post which you may find interesting: https://www.restartmed.com/hypothyroidism-acne/
Hi Leti,
It’s definitely more complex than just stopping the medication as you will need to address whatever underlying issue was causing low progesterone in the first place.
But it also doesn’t make sense to simply treat a number especially if it is causing more harm than good.
Hi Cleo,
I found this post searching something about side effects with progesterone cream, because everything I have read about it is good. However, since I started with bioidentical compounded (4 months ago), I have gained weight (4 kilos) and I feel pain behind my knees.
According to your experience, could you please tell me something else about any side effects? I am 40 years old, I was diagnosed with early menopause 7 years ago, and I just want to find the right way to improve my quality of life in these times.
Thanks in advance, and sorry for bothering you.
Regards
Rose
Hi Rose,
My story is long, and I’m happy to follow up with you over email. The short of it is that I gained almost 10 pounds while on progesterone cream the first time, felt bloated, weepy, etc., then stopped. I tried different doses and delivery methods, with more or less the same result. I found Prometrium affected me the most, and suppository and cream the least.
The latest time I tried it, I used a different compounding pharmacy and experienced the least weight-change side effects. It might have caused other side effects, including itching and hair loss. I maintained severe control over my diet (paleo) though so I gained no weight other than the first few days.
I’ve determined that either I cannot tolerate it, or it’s the compounding, an interplay among other another hormones (thyroid, adrenal function), or dysbiosis.
The only thing I liked about it was how my skin seemed to glow and the aid in sleeping, which I experienced on all delivery methods.
Hi Cleo,
Thanks for your answer. I am so relieved to hear that. Please donโt get me wrong, itยดs just that I had been feeling exactly what you feel and when I tried to find information about my symptoms, I just could read in forums, papers and abstracts about the miracle of the natural progesterone, so, is good to know that some else feel the same things.
I think natural progesterone could be good for many people but probably we are a very small group intolerant to this medication.
Actually, I am evaluating pros and cons of progesterone cream in my case. The only thing that progesterone could improve in my life, was exactly the same as you, skin and sleep. However, my libido does not come back, my vaginal dryness not improve at all, and plus, I have gained weight.
Nowadays, I am taking some medication (Thyroid extract, bio-identical progesterone cream and testosterone cream), however, I tried taking just thyroid, then added progesterone and after that I added testosterone, and I could see with progesterone cream, I started to feel a weird pain behind my right knee (just when I need to bend it), and one month later I had gained 1 kilo.
I just hope donยดt be bothering you, but, it is the first time that I know somebody with a similar condition like mine.
Have you tried testosterone cream? Was it easy for you remove those extra kilos?. I am reading a book about AIP (autoimmune protocol), how have the paleo diet been working for you?
Regards
Rose, I think progesterone is more problematic than is discussed. If I considered progesterone again, it would be on a reduced schedule.
Yes, I have tried testosterone cream, very lose dose. I am very sensitive to it (acne) and stopped. I lost the weight when I stopped progesterone, and continued working out and followed an eating regimen as I had in the past.
Paleo works for me pretty well. It’s a bit restrictive at times, but it’s the only plan where I did not have adverse digestive issues. (I have done AIP and FODMAP as well.)
Basically, I follow meal planning according to IFFYM, though limited to the Paleo foods. This is what works for me, but may not work for others due to their personal health issues.
Hi Cleo,
Thanks a lot for your response. If you agree, I would be more than happy to share our experiences by e mail. Maybe, we can help us each other. My email oblitus2008@gmail.com.
Regards
Hi Rose and Cleo
I am sensitive to progesterone as well. I have taken both progesterone before menopause, but could not tolerate more than 40 mg./day and took a day per week off. Menopause came along and bc of sadness and low energy, I took a little estrogen as well (Bioidentical as well). It went well for a few years with some ups and downs and adjustments as my hormones changed, but now suddenly I’m gaining weight without being able to loose it. I burst train, eat well, drink lots, sleep decent…mostly, but it’s tough to move the extra 10 pounds. I went off estrogen but I wonder if that’s not helping. I have lowered progesterone but that’s not working either. I’m quite sure it’s fluid retention. I’m trying dandilion tea and lemon juice. We’ll see! If you like, I sure wouldn’t mind staying in touch with you both and the my progress, as well as yours to see if we can troubleshoot together. Please let me know at bonitavp@gmail.com. thanks.
If youโre finding that fluid retention is a problem, I would strongly suggest you try keto. The first thing that happens as you fat adapted on keto is that you start shitting water weight. Iโve been on it for about two weeks and I havenโt seen that big of a change yet but my flash feels different to the touch because Iโve done so much fluid out of my body.
I’d have to disagree on the fluid retention point. The fluid retention that is reduced during keto has to do with balancing electrolytes which are different from the fluid retention from progesterone imbalances. There’s no guarantee that doing keto will improve your fluid status.
Hi
So I am 38 and had my ovaries removed a year and a half ago. I’ve always been a pretty active person and I have talked to my family doctor and had them take a blood test to see how my hormones levels are doing and they say they are fine but I have gained 15lbs and no matter what I have tried over the past year it will not come off. I’m only on .9mg of Premarin and.5mg of medroxyprogesterone.
I watch what I eat and I mix cardio with weights and some days just weights but the scale has not moved 1lbs in 3months with 4 days a week 1hr weight sessions and 1300 calories… It’s so disheartening…I don’t know what to do anymore to lose the weight.
Dr. Childs
I was prescribed by my Dr oral progesterone and would gain 7 pounds in 10 days each month. I took it for 2 months and gained 14 pounds. The weight would come on as I would finish my dose of bio-identical progesterone. Now 5 months later the weight will not come off even with being very diligent about nutrition, cardio and working out. I stopped CF and stick to just weights. Is this reaction to progesterone or just oral progesterone?
I just learned recently that if you have mycotoxin illness (eg, from mold), your body will hold onto fat, no matter what you do.
I have very high mycotoxin load from living in a water-damaged house (has your house ever flooded? Any leaks in the ceilings ever? Ever find mold on the walls/behind the walls?) If so, and if not PROPERLY remediated, you very well could have it. And will need to detox.
Drs will never mention this b/c they know nothing about it unless you see a holistic dr, most likely, which is how I found out. And took a myco test.
I also have some wacky hormone levels and hypothyroid. The combo is AWFUL for weight.
Do you use bio identicals to help you?
Hello Dr. Childs!
I am 48 and had some hormone tests done. My testosterone was 0.0. And DHEA’s 26L. My doctor is putting me on 25 mg DHEA every night because she said that females have to have testosterone and I shouldn’t be zero. My progesterone was 7.41. So she is putting me on 1ร day 100 mg Progesterone (Prometrium). Estrone was 70. Estradiol 133. I do get a lot of highs and lows emotionally. I tend to cry very easily, emotions seem to be all over, I also have bursts of anger and gained a lot of weight (still get my period every month). I just don’t want to start DHEA and progesterone if they will make it all worse lol. Especially if the progesterone may make me gain weight. Enjoyed your info and was hoping for your opinion. THANK you so very much for any time and help!
Hi, I have recently switched from a creme profile 10 to oral and have put on weight I not sure why but nothing else has changed can you suggest why ?
Hi Judy,
If you only changed your medication/hormone during that time then there is a high probability it’s caused the weight gain.
Dr. Childs: I have been on progesterone troches for over a year along with testosterone, estrogen and DHEA. My problem is out of control weight gain. I exercise everyday with an hour of running/walking up to 4 mikes and do weight training 3x a week. My diet is I would say good with limited alcohol and a few times a week some โsnacksโMy question is should I limit my progesterone to possibly every other day? Iโm at a loss, my naturopath insists that my weight gain not able to loose to my age, Iโm 63. Iโm thinking of changing Drs. To get another opinion. Iโm also taking Natur-Thyroid for hypothyroidism. Thank you!
Jody,
Did you ever hear back on your comment? I’m have been on hormone replacements (pellets) for over 6 months and taking 100mg progesterone. I gained 10lbs since then. I am on thyroid medicine andl60 years old. I would like to hear what the Dr. recommended and if you have learned anything that might help me.
Thank You!!!!
Hi Wendy,
It would be a good idea to check your hormones to see if the progesterone is really necessary. Many doctors will recommend it when it isn’t which leads to the weight gain side effect.
If someone’s cycle is severely irregular, when would the best time to test hormone levels be (i can go years without a cycle, then suddenly get a cycle again, but it’s super irregular, ie between 20-60 days)? Thanks for the great info on your website! ๐
Hi Shel,
If your cycle is irregular you can try to find out when you would ovulate and then counting 5-7 days after that for your testing, you can easily test for ovulation using LH strips.
Is there an age – after menopause – that one should not use progesterone? I had a complete hysterectomy at age 47. I have been clinically tested as progesterone deficient in the past, but stopped using progesterone cream around age 60. At age 67 I still have symptoms of deficiency (also diagnosed with Hasimoto’s and Hypothroidism) but am concerned about messing with hormones again.
Hi Rennie,
Not necessarily, it’s more dependent upon the person and their symptoms.
I have used progesterone in different forms (always bio-identical) since I was 42. I am now 59 and you do not deal with the issue of menopause in this article much at all. The other issue that bothers me in SO many articles is that “estrogen” is all lumped together when there are really 3 different kinds of estrogen and some like estriol are ok while the others are not. After menopause, the progesterone/estrogen issue is very different. I would like to see some information regarding your thoughts on these hormones (including the separation of all three estrogens) for a woman in menopause. How do the amounts of estrogens change; what levels for each is good; issues of blood work vs saliva; what type of estrogen is good to take if needed (I have taken some in the past with great results). Thank you.
Hi Lisa,
You can find more information about estrogen metabolites and how to use supplements in menopause here: https://www.restartmed.com/estrogen-supplements/
I believe there is a new generic prometrium. Here is the press release dated April 2017.
HYDERABAD, India & PRINCETON, N.J.–(BUSINESS WIRE)–Dr. Reddyโs Laboratories Ltd (BSE: 500124, NSE: DRREDDY, NYSE: RDY) announced today that it has launched Progesterone Capsules, 100 mg and 200 mg, a therapeutic equivalent generic version of Prometriumยฎ (Progesterone) Capsules in the United States market, approved by the U.S. Food and Drug Administration (USFDA).
Would you consider this oral progesterone?
Hi Marcel,
Yes, generic prometrium is oral progesterone.
Hi Dr. Childs,
Thanks very much for this post. I have somewhat a success story about progesterone.
I was diagnosed with Hashimoto’s and very low progesterone levels 7 years ago by my functional medical doctor . I have since been on Nature-Throid at varying doses . During that time, I was put on prescription progesterone bioidentical cream. I was later switched to prescription compounded pill 100mg. I had trouble conceiving for over a year until I was switched to Prometrium 150mg. I was able to get pregnant 2 months later. Healthy Pregnancy at 35 -no issues. I have since moved 4 hours away so no longer see same doctor. My progesterone levels have been in the “normal” range for about the past 2 years so none of my conventional physicians have addressed it . I have extreme PMS, unable to concentrate during that time and experience more bloating than ever. I maintain a healthy diet and exercise (keep a food log) yet I am unable to lose weight other than week two of my cycle where I then regain the lousy pound during PMS. It is so annoying. In the past, weight loss was slow with Hashimoto’s but not impossible as it is now. I am 39 and have been unable to have a second child. My OBGYN says this is likely due to my “TSH being low” (despite this always being the case being on ndt). My medical doctor has added Cytomel 5mcg to my Nature-Throid and I do feel better overall. No weight loss though. I am 20lbs overweight. Considering using OTC progesterone cream during days 16-25 as I had before. I actually forgot the cream is available without a prescription. Here is hoping for another success.
I have gained and lost this same 20lbs about every 3 years for the past 20 years have always done something about it but nothing is working anymore . I did Orangetheory 3-4 days a week for a year and half…no change. Ok now I read your blog and see I was stressing my body so that probably was a bad idea. ha! Thanks for all the info! I will be trying out the cream again days 16-28.
Hi Antionette,
No problem, I hope you found it helpful! You will find lots of information regarding weight loss on my blog, so I would poke around the various articles.
What is recommended if you are post menopausal with hypothyroidism and have adrenaline
insufficency
Hi Lucy,
Recommendations are based on the individual, not the disease state/condition.
I am using Progesterone Cream. I also have Hashimotos but have found that I have weight gain with Progesterone. I am using it everyday throughout my cycle, not just on day 14-28, maybe that is the problem. (I am not sure why my Dr prescribed it for me everyday). Do yo think it should only be used from day 14-28 if I am still menstruating (I am 51 yrs old). Thanks. Christina
Hi Christina,
That depends on many factors. The chances of you ovulating and having a normal cycle even though you are menstruating is fairly slim, so daily application may be ideal. It might be your dose as well.
Hi Christina,
I also used to be on it during the entire month . It was later changed to days -16-25. Not sure why either but I was able to lose weight easier then.
What does it mean to use 16-25?.
Can you please explain me?
Yes I suffer from a low Thyroid function,I would like to take the Progesterone cream.
What do you think
Hi Barbara,
You should evaluate your serum progesterone and estradiol levels prior to supplementation.
So compounded progesterone and DHEA by a pharmacist is NOT a natural product?(taken in a cream format)
Hi Heather,
You have to define what you mean by natural product. In most cases, if you are getting your medications from a compounding pharmacy they are likely bio-identical.
Hi Dr Child’s
I am about 2 months post mirena and was prescribed the combined pill, which I have been taking. I have definitely experienced the “crash” they talk about. Physically I feel better. By that I mean my back and knee joints suffer no pain now but mentally I have not felt myself.
I feel progesterone is a big player here. Have you any suggestions as to what road I should travel to try and feel my normal self again. I put on approx 2stone and am struggling to loose it.
Thanks
Lucy.
Hi Lucy,
If the problem is related to your mirena and synthetic progesterone then you will have to remove the mirena in order to get an accurate reading on what is happening with your progesterone/estrogen.
I also gained from progesterone can you get off compounded hormones by just stopping or should you wean off ? I have been in them about 18 months ?
Hi JJ,
That depends on how much you are taking and how long you’ve been taking it and if you are using cream/pills.
Hi
I noticed most of everyone have a complaint with weight gain but mine is the opposite. I was put on oral biodentical progesterone 100mg., and I’ve been having side effects such as irritability, unable to go to sleep, lack of appetite,and feeling worse than before in a sense. I also have gastritis in which I had already lost weight from it but since I’ve been on the progesterone it s
like its decreasing my appetite even more. It makes me feel more like pregnancy symptons. Could the dosage be too much for me or maybe the wrong method? I feel like I am literally losing it.
Hi Mary,
Both of those would be considerations given your current symptoms.
I just turned 30 years old and I have been prescribed a generic progesterone 100mg at bed time by my holistic doctor. I’m suppose to take it day 7-21 the first 3 months and then day 14-28 the next three month following. I was also advised to take 100mg of pregnenolone and raw adrenal tablets. I was diagnosised with stage 3 adrenal fatigue, hypothyroidism, low progesterone and low pregnenolone. I have already gained 18lbs in 4 months and after reading a few things I’m afraid I’m going to gain more weight from my high dosage. I’ve only been on them a few days but now I’m thinking maybe I should have a lower dose? Do you think it’s okay? She said my levels should have been between 13-21 and they were a 2. I don’t know what any of that means but I’m just concerned because I’m generally freaked out by taking any pills (I don’t even take pain relievers when I have a headache) any in put??
Hi Danielle,
I can’t comment on your specific case because there isn’t enough information in your post for me to say one way or the other.
Greetings, I am a 62-year-old female who has been on natural progesterone supplementation for around the last 6 years. I’m thin and athletic. When my hormone levels were tested, I had virtually zero progesterone, but also had almost no estrogen. I have slowly gained 5 to 6 pounds over the past 6 years. When I went on a 2 1/2 week vacation recently, I didn’t take my progesterone cream. During that time I lost 5 pounds. Since I have virtually no estrogen, does it make sense to continue using natural progesterone? Thanks, Debbie
I can’t ever seem to get anything in balance, so am 50 pounds overweight on a 5’1 frame. My leptin is 30 and I know it should be less than 15, preferably 10. So I think that’s the problem. But nothing seems to address that problem. I have hashimotos and take t3/t4 compounded, and sometimes only T3 as t4 doesn’t really like to convert. I suffer from fibromyalgia and have been all over the country looking for answers. I have had a hysterectomy and been on bioidenticals most of my life. It doesn’t matter if I increase my thyroid, take progesterone or estrogen, I can’t lose this weight. I know some doctors supplement with amylin (symlin, byetta)) but my naturopath isn’t comfortable with that. What can I possibly do? See another doctor? I’ve been to several endocronologists and they are no help. Any suggestions?
Hi
I was diagnosed with high estradiol and normal to low progestrone. I’ve been taking oral progesterone now for 2 months. I’m on cycle 2 but don’t notice any physical changes other than weight gain. I’ve currently had my dose from 50 to now 75. Is there another reason why I’m gaining weight?
I was over using cream & oral at same time for every day x3 mos & have gained 30lbs. Didnt realize I was over doing it. Taking a holiday then gonna cycle days 15-24 at 100 oral to start then 200 if need be.
gonna lower my E oral to .5 and dhea mg every other day with goal to keep E around 100 ish
I am 40 started perimenopause early at age 35. Before HRT I was at E 15, Prog. .5 and T 4. I started bc I had gained 10 quick pounds & extreme fatigue.
then, over did thr HRT & became a blimp. moe ow starting my new plan fingers crossed. May add DIM once a week to metabolize excess estrogen to be safe. I would rather be under 100 than too far over.
Hello Dr. Childs–you asked for a story, well unfortunately, I have one. I’ve had migraines since I was 16 {I’m now 52}. I’ve never had a weight problem, I’m a vegetarian, fitness instructor, usually weighed 115 lbs. The migraines became progressively worse and more frequent over the years, *usually* only happening at my PMS time. I have had a hysterectomy and one ovary removed. When I was 49 I had all heck break loose, a 6 day migraine, with everything it entails. I went to the doctor who said my FSH was 156 and welcome to menopause.
I couldn’t get 6 day migraines every month. Imitrex would work for a few hours but then the pain would return. This was new. Someone told me progesterone cream took care of their migraines. After so many years and no help, I was desperate. I tried it in January 2015. By Valentine’s Day 2015 I was 10 lbs heavier. I went off it. I read that I should have stayed on it because it needed to just overcome ‘estrogen dominance’ {which I never was} and then I would lose the water weight it put on me. Like an idiot I went back on it, the cream—and gained another 10 lbs. By this time I was frantic. My only relief was at PMS time every month, I would lose 4-5 lbs and be hopeful it was staying off—but it always came back.
I got off the cream for a year and a half and nothing happened. I took supplements (including adaptogens} and worked out and didn’t lose an ounce. I went to a ‘bio identical hormone specialist’; she had me do the 24 hour cortisol test which showed at certain times of the day it was over whatever their chart showed as high. My cortisol was very high at late afternoon. It made sense because during the progesterone cream I was falling asleep at work in the mornings when it was low. She put me on phosphatidylcholine which did nothing.
She put me on a bi-est cream, 80/20 and progesterone pills. I was terrified to do it but desperate. I gained another 10 lbs. I’m a tiny framed woman and now I’m always in pain, all my joints including my elbows hurt me all the time. Leg discomfort, all the time. Tachycardia. Very big pregnant looking tummy. The works.
I stopped seeing her and went to someone else who noticed that my estriol was {but is no longer} extremely high at the time I saw the previous specialist. My estradiol was -15. So right now I am on an estradiol patch. I’ve gained a couple of pounds.
I’m just about resigned to always carrying around the water and fat weight for the rest of my life. I just wish my joints didn’t hurt so bad and I felt better. This fitness instructor is no fitness instructor anymore. It’s hopeless, isn’t it. I feel in my desperation to stop my migraines I ruined my body forever. Oh did I mention depression? ๐ Thank you for listening. I found your website very informative and I’m so glad someone out there knows something about the delicate hormone balancing act.
Hi Denine, interesting story. I share some similarities to your experiences, tests, etc. Honestly except for the sleep benefit which eventually verged into lethargy, I feel better without progesterone.
VERY glad you do, Cleo. I’m a wreck. I hope you continue to feel better.
Hi Denine,
I am sorry to hear your problems. Something similar happening to me. Denine, the very first time that you tried Progesterone cream, it was just Progesterone or combined with estrogens?
Hello, I am 50 and just had my 3 month check-up after being on Progesterone cream. I have gained 12 lbs in 5 months. The first two I went off the pill so that I could have accurate hormone testing and then I went on the cream, DHEA, Vit D and adrenal drops. I could feel the weight coming on daily. I eat better than I ever have as far as clean. I am active, too. I feel much better on the cream but hate feeling chubby. My dr. drew labs the other day to see if I am getting too much. The cream makes me calmer, sleepier at bedtime and able to handle stress.
Hi,
How is this 20-40mg determined? My doctor put me on 100-200 mg depending on the time of month to help my migraines. It definitely has helped my migraines and acne but I am now gaining weight, which is something I have never had to deal with before. Im 31 and very lanky! I have read in other posts that 20-40 mg is way too low and can cause negative side effects that mimmick estrogen-dominance. Have you seen this before? Thanks!
Kimmy
Hi Kimmy,
Dosing depends on if you are taking it orally or transdermally. The 20-40mg dosing schedule is recommended for transdermal application. In addition, taking progesterone in general will not cause estrogen dominance as progesterone is a direct antagonist to estrogen. The opposite is true however, as there is cross reactivity between progesterone and estrogen receptors at high dosages.
I completely failed to ask a question—my sad story being what it is, now that I’m on an estradiol patch now, should I also go on bio progesterone cream also to hopefully lose this water and fat weight?
Hi Denine,
While progesterone is an antagonist to estradiol, it doesn’t necessarily mean that taking it will undo the consequences of taking estradiol. This depends on a number of factors including how much estradiol you were taking, how long you were taking it, existing hormone imbalances, existing and starting progesterone level, etc.
Hi Doctor. I’m on estradiol to undo the consequences of being on progesterone. ๐ I laid it all out in my original post above. I’m a mess, a wreck, just praying for my life back. ๐
I am 50 yr old, naturally thin. 5’9″ usually 135-140. Started on progesterone cream and gained 15lb, felt horrible, depressed,body dragging. I think too many people, websites, books promote progesterone use and to increase if problems occur…incorrect info in my opinion. I personally do best on BHRT DHEA/test. Cream and Est. cream and no progesterone…when i had progesterone it is much too difficult to balance and horrible side effects for me and weight gain is a NO NO!
Hi,
Im an athletic, fit person who went on bioidentical hormones 14 years ago. The problem is that I gained a lot of weight. My breasts went up two sizes and have been so tender, I Feel like they could explode. The doctor at the ‘aging clinic’
prescribed 10mg of testosterone, 10mg of estrogen and 120mg of progesterone.
when I went to the new gynecologist last month she suggested I go off the medication because of the side effects and the dosage.
Guess what? A month off the medication and I feel so much better. My breasts have dropped a cup size and they don’t hurt. Also interesting is that feel much calmer, easy going and positive. I don’t have to work so hard to manage my moods.
I recall in my 30’s that I used to get PMS for a few days each month where I struggled not to lock horns with anyone or go on a cray cray ‘crying jag’. Imagine, bringing that kind of mood onboard 24/7 with these massive hormones.
I feel so calm an happy now !
I am wondering how the aging clinics can get away with prescribing such massive amounts of hormones.
any thoughts?
Testosterone made me sleepy and very hungry, and it also gave me headaches (probably due to being sleepy).
Hi Beth
If you originally went on HRT bc you ‘needed’ it, then you were likely put on doses that were too high for you. If the doc only put you on them for anti-aging purposes, then you gained weight bc your body was telling you you didn’t need them. When you went off your HRT years later you went back to normal. Lucky you! But sometimes in menopause you can have severe hormone fluctuations that may require ‘small’ doses of HRT. Hopefully not.
6 yrs. ago I was still on the pill. I had read about progesterone and started using the cream twice a day. Honestly, without changing anything else, I very easily lost 13 lbs. in 3 months. I am not a good dieter so this was totally out of the norm. I thought I was sick! And my thighs and butt shrunk! Then for a reason I can’t recall, I quit. And that weight came right back. Fast forward to 2 yrs. ago. I tried it again to lose weight, and went off the pill simultaneously thinking that would double my chances. My thighs grew out of control and went up a pant size. I went off the progesterone and, in a couple of months, my pants fit again. Remembering the success of the first time, I have tried it occasionally for a couple of days, get scared,and quit. I just got off another 2 wk. sycle and I gained weight during. So, I am disgusted and I am done. I am 56, menopausal and, thankfully, symptom-free as far as I can tell. I also take DIM, and have for a couple of yrs. I keep reading these articles about how great progesterone is and you can’t use too much. I am done messing with my hormones unless something drastic happens. Now, just hoping I can reverse this latest weight gain.
Remember that your hormone levels change as the years go by, so HRT needs adjustment as well.
It’s just easier to gain weight when your metabolism slows down.
Much of gaining weight while taking progesterone at too high a dose results in water retention. I’m 62 and the older I get the lower I have to go with my progesterone. I’m at an impass right now but I’ll figure it out again. I’m giving my body a week off right now to clear the receptors. Osteoporosis runs in my genes and progesterone in small doses (even as low as 6mg. Per day can help to build bone. So if that’s all I need, that’s all I’ll take.
Diane, I had a similar experience with progesterone cream. In my early 40’s I used it and lost weight effortlessly. Now at age 51 I tried it again and it causes inflammation and weight gain. The exact same dosage and bioidentical cream as the first time. I too use DIM, as well as calcium d-glucarate, which is supposed to help with estrogen detoxification and metabolism. I find I feel best using both those supplements without progesterone. Haven’t had any menopausal symptoms yet.
I recently had a endometrial biopsy due to cystic hyperplasia and thickening of the lining of the uterus. My Gynecologist said if the biopsy comes back normal, she will put me on Progesterone for 6 months. Then do another ultrasound and biopsy then. I’m scared to death to go on Progesterone due to the side effects – especially possible weight gain. Do you know if there are alternative options? Thanks, Kelly
My 14yo daughter has Hashimoto’s/hypothyroidism. She takes an NDT brand called WP, but although her numbers have sometimes been in range (never optimal according to the thyroid experts on the internet) they are mostly below range…so basically, her thyroid is still not working correctly after years of taking meds. She also has high cortisol (morning, noon, and evening). She has always struggled with weight even though she is very athletic and plays many sports. She’s 5’7 so she can carry the weight better than most, but she still looks dough-y as she carries it all in her stomach and thighs. She recently went to a BHRT doctor that was supposed to be a thyroid expert. She did what every doctor does…increased her meds again…but also determined that she was low in Progesterone based on symptoms and a good guess. Blood work confirmed it and she put her on the oral Progesterone (not The Pill, just progesterone). She was told to take 100mg before bed and to take it everyday. Well, she’s never had her cycle since starting it (3 months) and has gained weight, especially in her thighs. Now that I am reading on this blog about others gaining weight while using progesterone (with a few specific references to the thighs) I am connecting some dots. I decided to stop the progesterone, hoping her cycle would come before she starts high school next week and even before I read this blog, I thought she looked like she lost a bit of weight. Now I am wondering if I should bother putting her back on the progesterone since I don’t think it did anything for her. If she doesn’t get her cycle soon, is it worth testing her progesterone levels again? And when?
Hi Sarah,
I would recommend against the use of progesterone in someone that young, if you can manage her thyroid correctly then her sex hormones should improve.
Here’s my question, I recently started on progesterone 100 mg at bedtime. I’m experiencing tremendous blotting not to mention weight gain. Besides the progesterone I wear a patch called Climara pro estradiol/levonorgestrel 0.045/0.015 I change it out every week. Am I getting to many hormones??
Oh I am also feeling fatigued more then usual
What should I do. Please help I truly don’t like this feeling at ALL!!
Thanks for your help.
Hi Lisa,
It’s impossible to say what is causing what while you are taking both bio-identical progesterone, synthetic progesterone and estrogens. Your symptoms could be related to any of the medications listed or simply due to the dosing, you will need someone to help you tease out the specifics.
I am having trouble gaining weight. I have lost 20 lbs in 7 months. I eat and cannot seem to gain. My hormones were tested a couple months ago by bloodwork. My progesterone was 0.2, estradiol 15.3, testosterone 7.6. I also suffer from depression, rapid heart rate, severe anxiety, panic attacks, agoraphobia, hair loss, dry skin, dizziness, blurred vision. I’m 37 years old. Would I benefit from progesterone cream?
Hi Christy,
You would benefit from a complete hormone profile including thyroid assessment and evaluation for hyperthyroidism.
I thought I was going crazy until I read this article. My dr increased my progesterone and I put 10 pounds on in a few months. I can’t seem to drop them. I’m going to ask to have my progesterone level dropped. I hope the dr listens. Thank you for this blog. I have hashimotos also. Fun times!!
Hi Becky,
No problem and I hope it helps!
Hi,
I am strongly considering the Nexplanon implant for birth control (I am not a candidate for an IUD and I do want to breastfeed when I give birth in a few weeks and I want something more than 98% effective as birth control).
I used to be 115 lbs and three children later and three rounds of the mini-pill later, I am currently 34 pregnant and 180 lbs. I was 155 when I conceived (while on the mini-pill.
I have been on the mini-pill and each time gained more weight. I definitely have an increased appetite and I retain water.
Will the Nexplanon likely make me gain weight? Prevent weight loss? If so, how can I combat that since I don’t have many options for birth control…
Thank you in advance for your help!
Good article but you need to include those of us that have had a full hysterectomy. Thanks
Dr. Childs,
My doctor was fairly certain that a submucosal fibroid the size of a golf ball was the cause of my constant bleeding and severe cramps. I had a hysteroscopic myomectomy followed by a D&C on September 15th. Though there was initially a reduction in the symptoms, that lasted only for a few days. Severe cramping and daily bleeding are back with a vengeance. An intensified dose of birth control over the course of a week stopped the bleeding and cramps for about a week, but as soon as I was back on normal dose the bleeding and cramps started again. I do not have endometriosis, and pathology indicates no uterine cancer. So, we can only conclude that this is a hormonal imbalance. The stress levels I have had this year are off the charts, partly related to managing my mom’s dementia care and transition to long term care, and then subsequent associated circumstances. I am 43. I have a healthy diet (lean proteins, no processed sugar, only whole grain breads and pastas in minimum consumption, lots of fruits and vegetables. I exercise regularly. I am not overweight. I started taking chasteberry, milk thistle, flaxseed oil, and vitamin B complex a month ago. I asked my doctor about natural progesterone and she gave me the options of provera or norethindrone. Before I ask her about prometrium, I want to try bio-identical cream. Herein lies my problem. All of the advice I can find anywhere discusses the day of your cycle on which you should start and stop the cream. I have been bleeding every single day since June 15th with the rare exception of the few days of relief I had after surgery, so how in the world do I determine how and when to start and stop the cream?
Thank you,
Heather Owen
There are many ‘natural’ hormone specialists that can help you. It sound like you are high in estogen compared to progesterone, and that you could use Bioidentical progesterone to rebalance. Stop using pharmaceutical HRT. Go see a doctor who will help you with a Bioidentical approach.
Hi Dr.,
I am 61, post menopausal and have been on bioidentical estrogen(intravaginal 2mg) and progesterone pills(200mg at night) for 1 year. should I get my levels tested again to see how they look now? They both were extreme low when I started. I have gained weight even though I exercise and watch my diet,about 10 lbs since I started! ๐ I sleep great but the weight gain is distressing. I tried the testosterone (also extreme low) but didn’t like how I felt on it (angry). I am thinking of going down to 1mg on the estrogen. Both are from a compounding pharmacy.
Thank you!! Sandy
I am 30 years old, since January 2017 I was diagnosed with hashimotos, and in April I was diagnosed with stage 3 adrenal fatigue from saliva cortisol labs. My DHEA, Progesterone, and estradiol were the levels of a 70 year old. I have been supplementing DHEA, and taking bioidentical estrogen and progesterone creams from my local compounding pharmacy. I also have been taking adrenal support supplements. And I take Armour thyroid. I feel better and will be taking another saliva cortisol test next month to see where my levels are at now. I am frustrated with the weight gain though. I have gained 15 pounds in the last year. I cut out gluten and cows milk from my diet, but I have a hard time tolerating post exercise soreness. It leaves me in bed for days. I don’t understand why the pain is so bad. I used to be a distance runner and I could deal with post exercise soreness. Now the pain feels too much to handle, it’s extremely frustrating..I just want to feel like my old self. Any insight or advice would be very much appreciated.
Hi, my doctor put me on progesterone tablets to stop heavy menstrual bleeding. It has caused weight gain and breast tenderness.
Do you suggest a natural cream may be better? Would I need to take this daily to stop menstuation?
Would appreciate your guidance Dr Childs
I started using the cream and on day 2 of using it I started my period. I’m 51and my periods are irregular and typically only occur every three or four months. I know getting my period isn’t a coincidence. I’ve read that it is a sign my estrogen levels are high if you get your period while taking it. My question is should I continue taking it since I started to bleed or stop. What is your schedule recommendation?
Hi,
Thank you for the article! SO informative! I’m on my 4th months of Bi-est/T/D Versa/1.25/.5/10mg/Ml cream. I take .5 daily of this and 1capsule of progesterone 50mg daily. These are both compounded locally.
My labs in October were estradiol:19 FSH:69 LH 59 Progesterone 8.2 Testosterone 22. My labs prior to HRT were all very low. My Dr. said my hormones were non-existent.
I started these as I’ve been dealing with Chronic Fatigue and a number of other ailments for a few years. I stopped menstruating at age 43 with no menopausal symptomes until a few months ago when I started experiencing night sweats.
My Dr. monitors my thyroid and currently I’m on a low dose of WP thyroid.
I can’t tell much difference at all on the hormones. My skin and hair are as dry as ever and sleep hasn’t changed much. I did put on at least 10lbs and gained visceral belly fat and facial fat. I’m a very petite person so this is quite a bit of weight for me. I am extremely active and maintain a grain free, paleo, high fat diet.
Would you recommend I stop the hormones? I just don’t right on them and the extra fat bothers me as well. I gained alot of weight on the BCP pill in my twenties and I do have a history of TIA’s on them as well
Thank you for your help!
Would I benifit from prometrium made from peanuts or oral progesterone made from wild yam.I have PCOS and graves disease. I have gained weight since using Ona’s oral progesterone.
I am a 70 year old woman who has been fighting with hair loss and weight gain since i started menopause in 1996. I am currently on compounded estriol ,05 mg. Progesterone 250 mg. T-3 15 mcg. I have gained so much weight (15 pounds) which is a lot for someone 5 ft. I also take iodoral for my thryroid condition. I am thinking about doing a saliva test to see where i am at with my progesterone and estriol. I know my cortisol is high, because of the stress of weight gain and hair loss. Trying to decrease my stress is almost an impossibility with all that is going on. I would appreciate any feedback. Thank you in advance!
What do you think about the all natural progesterone oil ? Essential oils came out with one but not sure how I feel about it . Wanted to know your thoughts . Thank you
Hi Debra,
I’m not familiar with it or what’s inside of it so I can’t really comment on it!
Hi,
I am 47 and have PCOS. I have never had a weight problem in my life and fall last year started feeling so exhausted I couldn’t function (along with severe arthritis from a car accident.) My doc said I was low on progesterone and put me on 30 mg cream daily- since then I’ve gained 1.4 pounds A WEEK. Could it be too much? I’m so confused as they don’t want to retest me. I have taken this in the past (when pregnant) and not gained weight. HELP!
Hi Dr. Childs,
I am 48 years old with very regular cycles, though they are getting closer together (every 28 days versus my normal every 35 days). Over the past 3 years my PMS symptoms have increased dramatically- irritable, hungry all the time, weepy. I started using the progesterone cream that you recommend on your website 5 months ago to help with these symptoms and it has helped with my moods but now I am noticing even more increased hunger and a weight gain of 7 pounds. I use the cream during the last two weeks of my cycle. Do you think the progesterone is causing the cravings and weight gain?
Hi Jennifer,
If nothing else has changed then it’s possible that progesterone is causing some of these new symptoms.
Hi! Im trying to figure out what caused a sudden 13lb weight gain. I am 45, not in menopause. Recent bloodwork showed testosterone levels at 22 and progesterone at .9. Decided to take a friends advice who runs a hormone replacement clinic. She put me on bio identical testosterone pellets and 100 mg progesterone in the troche that goes under the tongue. level raised to 1.9 so she increased it to 150mg. I gained 7 lbs immediately then another 6 before the first 3 months of therapy were complete. now Im bloated, holding water, sore nipples and cannot drop a pound to save my life. Mind you I’m a fitness professional (pro physique competitor) and know what I’m doing and always stay around 18% body fat so this feels like I’m in an aliens body. I”m about to stop everything asap. but i cant help wonder if its just the progesterone causing this.
Hi Jill,
It’s very unlikely to be related to your testosterone, so in the absence of other issues that you may have not listed your weight gain is most likely related to progesterone – but you’ll need some blood tests to make sure!
I was prescribed oral progesterone 4.5 years ago based on the results of a saliva test. I was also recommended a battery of supplements, and I took most of them. My chief complaints had been insomnia and weight gain that isn’t controlled by diet and exercise (which I do a lot). At age 35, weight weight came on suddenly over the course of a few months–after years of holding steady at one number.
At first while on the progesterone, I gained maybe 4 lbs (I assume water weight), but I ended up losing weight and getting back to the weight I was before the big gain at 35.
Blood tests this past week show a similar story to the saliva test, but possibly worse. I’m not even in the reference range. I’ll see how it affects my weight this time.
What method of testing do you recommend to determine if a woman who has gone through menopause or is elderly (64) has too little progesterone? Thanks.
I have been taking compounded progesterone 100mg for 3 months and I have gained 10 pounds. Can one just stop taking it immediately or do you have to slowly taper off? I eat a healthy diet and I have started eating only 2 meals a day because of the weight gain. I was prescribed it because of adrenal fatigue, but the weight gain is causing more stress! Thanks
Dr. Childs, I would love your insight into my situation. I’m 32 and I started progesterone because I had a partial hysterectomy, experienced loss of sex drive and sleep interruptions, foggy mind, acne, and just didn’t feel myself. The dr noticed my progesterone levels were a little low so wanted to just try 100mg of synthetic progesterone (oral). I sleep a lot better but still feel the other symptoms and now have breast tenderness. It just seems he threw that out there to try it? What would you suggest I do next after reading this article? It sounds like synthetic hormones are a bad idea? I would love your advice, thanks!
Hi, Thank you for this information. I have had adrenal dysfunction and gut problems for a few years now, and couldnt lose weight no matter what i did. Last year, i went on oral progesterone (all my hormones are under functioning) at 100mg and i started dropping weight like crazy and i physically felt great. I had no cravings and a decreased appetite, but I was emotionally a mess! So i went off it, cause i felt so mentally stressed and couldnt stop crying. This year my progesterone is still low, even using the dermal ones (which never felt like it was helping much), and plus i dont get the great weight loss/appetite benefits, so i went back on oral at only 10 mg. I am not having any of the digestion benefits and its putting me to sleep around 4pm daily I feel like ive been drugged. I dont understand how the larger dose never did that, but this one is. Any ideas? Maybe it goes away? Its just my first month back on. My doctor is pretty out of thoughts at this point. Thanks! Erin
Jan 2017 out of the blue started having bad panic attackโs that is totally out of character for me. After my doctor just wanted to put me on anti depressants which I didnโt want to do because Iโm not depressed, I wanted a second opinion because I feel like something is off. I found out thru a saliva test from a compounding pharmacy that my estrogen levels where low and my progesterone was low and I had high testosterone. So a I got referred to a doctor that deals with bio dentical hormones. She put me on 100 mg of progesterone pills August 2017 at night before bed. I think it helped with sleep somewhat but was still panicky feeling. Itโs been 7 months of being on the 100 mgs, I took another saliva test to see how I was doing and my estrogen and progesterone results where even lower than when I started 7 months ago. So they think Iโm not absorbing the pills? I was 29 years old,160lbs (5โ7) when I started 7 months ago and Iโm thankfully the same weight, I exercise regularly and eat healthy but Iโve had the hardest time losing weight even before taking hormones. Now Iโm 30 years old and my doctor wants to put me on 25 mg of progesterone cream (which I started this morning 3/4/18) in the morning and keep taking 100mg pills at night. After seeing this website Iโm really worried I could put on more weight. I asked my doctor about it and she says she hasnโt heard any of her other patients that are on progesterone complain about weight gain. Iโm just wondering if taking it every 12 hours in pill and cream form is good to do? Iโm super confused. Iโd love some input.
Thanks
-Stephanie C