Berberine 500+ Combo Berberine + ALA Weight Loss Formula

Berberine 500+ | Berberine HCL & ALA Weight Loss Formula


This powerful combination of berberine plus alpha lipoic acid is designed to promote hormone balance, reduce fat mass, increase muscle mass, reduce blood sugar levels, support gut health, support cholesterol, and lipid metabolism, and reduce inflammation when used in combination with lifestyle modifications. 

Purchase this product now and earn 270 Points!

Manufactured in The USA

Third-party tested for purity

60-day Money Back Guarantee

Frequently Bought Together

berberine 500 front bottle image high res + essential t2 front bottle image 1500 x 1500
Price for both: $95.98


Will taking Berberine 500+ help you melt off body fat while simultaneously allowing you to increase your muscle mass and metabolism without any other work on your part?

Definitely not!

But it is a well-researched and well-formulated dietary supplement that can help you more easily lose weight, build muscle mass, and balance your hormones if combined with lifestyle changes like intermittent fasting, eating a whole food diet, and exercising regularly.

YouTube video

And when you purchase any supplement from Dr. Westin Childs you get the added benefit of knowing:

  • Every single supplement is third-party tested by an ISO-accredited lab for purity, contaminants, microbes, mold, and heavy metals.
  • Total transparency is the standard when it comes to reviews and opinions from people who have used our supplements (we have a 99% transparency medal from our third-party review aggregator
  • All of my supplements are made in an FDA-inspected and GMP-compliant facility.

How Berberine 500+ Helps with Weight Loss

When it comes to berberine, you don’t just have to take my word for it when I say that it works.

The research is also pretty clear on the matter:

waist and hip measurements in patients using berberine over 13 weeks.

Research has shown that berberine has the potential to help lower blood sugar and insulin levels (with some studies showing it’s just as powerful as the medication metformin).

And it is through this mechanism (and a couple of others) that berberine may be a solution to persistent weight gain and weight loss resistance.

Here are three documented ways that berberine may help accelerate weight loss:

#1. Berberine helps reverse insulin resistance and helps lower blood sugar.

You can think of insulin as a “fat-storing” hormone in your body.

Along with leptin, insulin controls and regulates the breakdown of fat cells (or not) in your body.

When insulin levels are high and insulin is no longer functioning as well as it should, you are said to be in a state of insulin resistance.

And it is this resistance syndrome that makes weight loss so difficult.

In insulin resistance, your body produces higher and higher levels of insulin which constantly send the signal to your body to store calories in your fat cells.

As many as 50% of the population in the United States have some degree of insulin resistance which makes this a top priority for anyone who is trying to lose weight.

In a randomized, double-blind, placebo-controlled trial, berberine was shown to reduce waist circumference, blood pressure, triglyceride levels, glucose levels, and insulin levels.

#2. Berberine increases the number of mitochondria in muscles.

Mitochondria produce energy for your entire body and help regulate your basal metabolic rate (also known as your metabolism).

The more lean muscle mass in your body, the higher your metabolism, and the easier it is to lose weight.

When it comes to weight loss, your metabolism may be the most important metric for determining if you will lose weight and if you will keep that weight off.

With that in mind, it’s important to keep your metabolism functioning optimally and prevent it from slowing down.

Part of your metabolism is controlled by your thyroid and another large part is controlled by the number and efficiency of mitochondria in your muscle cells.

Anything that helps to increase mitochondrial density may help increase your metabolism.

And berberine has been shown to do just that through its influence on the Smad pathway.

Regular use of berberine in conjunction with regular exercise may help improve skeletal muscle mass which contributes to metabolism to make your weight loss efforts more effective.

#3. Berberine directly increases brown tat (the good fat).

Most people have become accustomed to thinking that all fat is bad but that isn’t the case!

White fat (white adipose tissue) is the fat that most people are trying to get rid of when they want to lose weight.

Brown fat (brown adipose tissue) on the other hand, is a more beneficial fat becomes it helps regulate your metabolism by producing heat.

In other words, if you are trying to lose weight or fat mass, you want to increase brown fat while decreasing white fat.

And that’s exactly what berberine has the potential to do.

Berberine has the potential to assist in converting white fat into brown fat which can provide a nice boost to your metabolism.

The Benefits of Alpha Lipoic Acid

Each capsule of Berberine 500+ contains berberine and alpha-lipoic acid (or ALA for short).

All of the discussion so far has been directed at berberine, but ALA also has the potential to help with weight loss as well.

And, much like berberine, ALA has several scientific studies which show it is efficacious.

So how does ALA work?

Alpha-lipoic acid exerts its effects by acting as a powerful anti-inflammatory agent.

By reducing inflammation ALA may help reduce cellular damage over time by cleaning up free radicals.

Studies have shown that this reduction in inflammation may also be one of the main reasons that ALA helps with weight loss.

These studies indicate that the more ALA you take, the more weight you lose.

ALA 20 week weight loss results

ALA has also been shown to positively impact insulin resistance, lower blood sugar, increase mitochondrial energy production, and more.

Berberine was combined with alpha-lipoic acid because they work synergistically with one another.

Dr westin childs photo

Why Dr. Childs Recommends It

“Berberine and alpha lipoic acid are probably two of my favorite ingredients for weight loss because they target unique pathways, they are very effective, and hardly anyone knows about them.

Berberine has the potential to do two very important things: help you build muscle mass and lose fat mass while also balancing fat-storing hormones like insulin. It’s a great option for anyone trying to lose weight.”

How to Use Berberine 500+

  • For mild weight gain (5 to 20 pounds over ideal body weight) or mild insulin resistance -> Take 2 capsules twice daily, 2 in the morning, and 2 in the evening, with or without food. Combine with a whole food diet, regular exercise, and intermittent fasting.
  • For moderate weight gain (20 to 45 pounds over ideal body weight) or moderate insulin resistance -> Take 2 capsules twice daily, 2 in the morning, and 2 in the evening, with or without food. Combine with a whole food diet, regular exercise, and intermittent fasting. You may also consider additional treatments in the form of supplements and weight loss medications in this category.
  • For higher levels of weight gain (50 pounds or more over ideal body weight) or higher levels of insulin resistance -> Take 2 capsules twice daily, 2 in the morning, and 2 in the evening, with or without food. Combine with a whole food diet, regular exercise, and intermittent fasting. You will also likely need further support in the form of prescription weight loss medications, hormones, and additional weight loss supplements in this category.

Frequently Asked Questions

Yes, but perhaps a better way to state how it works is to say that it supports your existing weight loss efforts and makes those efforts more effective.

Berberine 500+ will put your body into a state where weight loss is more effective and easier, but it is unlikely to cause weight loss without any other effort or input on your part.

For this reason, you should always combine Berberine 500+ (or any of my other weight loss supplements) with things like a whole-food diet, regular exercise, and intermittent fasting.

Using my weight loss supplements in this way will make your efforts far more effective and help you obtain your goals.

That is a great question!

If you want to lose weight, keep it off, and change your body into a well-oiled fat-burning machine then you need to be doing more than just taking supplements.

Yes, supplements can absolutely help, but they don’t replace important lifestyle changes like diet and exercise.

No matter what you are doing, these need to be done as well.

Based on my extensive research in helping patients with weight loss, here’s what works best when using Berberine 500+:

  • A whole food diet (I’ve seen just about every single one work including the ketogenic diet, carnivore diet, low carb, vegan, whole30, etc. Just make sure to find a whole food diet that works for you).
  • Regular exercise at least 3-5 times per week. My preference is weight lifting as it helps with weight loss and building muscle mass but pretty much anything can work here. If cycling is your thing then go for that. If you prefer pilates or yoga or something less intense, more power to you. What you do is less important than making sure you do it consistently.
  • Intermittent fasting. If you are overweight then going for several hours to even a full day without food is incredibly helpful for balancing fat-storing hormones like leptin and insulin. My favorite fasting protocols include 2, 24-hour fasts each week, one meal a day, every other day fasting, or 16-hour fasting windows (see more information below).

Fasting is simply going without food for a set period of time and it’s been a regular part of cultures and religions for thousands of years.

Taking advantage of fasting as a therapy allows you to get more benefits out of weight loss therapies including supplements, medications, and even exercise.

If you are new to fasting, here are several protocols that can be considered (I’ve seen them all work):

  • 2, 24-hour fasts each week: This fasting protocol is easy, you just take 2 days out of the week and you go without food for a 24-hour period.
  • Every other day fasting (3, 24-hour fasts each week): Every other day fasting is very similar but you can pick whatever 3 days work best for you based on your schedule. Most people who use this method do 1, 24 hour fast on Monday then again on Wednesday then again on Friday.
  • OMAD (one meal a day): One meal a day is exactly as it sounds, you eat one gigantic meal each day.
  • 16-hour fasting windows: This is similar to the one meal-a-day plan but it allows you to eat for an 8-hour window (as opposed to just one meal) every day. This means that each day you will be fasting for at least 16 hours. This is an easier way to jump into fasting if some of the other options seem too intense for you.

Don’t be afraid to play around with these fasting protocols to find something that works best for your body and your situation!

No matter what you do, just make sure you are doing some form of fasting if you are trying to lose weight!

For best results take 2 capsules of berberine 500+ in the morning and 2 capsules in the evening with or without food.

If you take thyroid medication take this supplement 30-60 minutes away from your thyroid medication.

How quickly you see results depends on how you are checking for those results and factors including how resistant you are to weight loss.

Most people, however, should expect to see changes after about 4-6 weeks of daily consistent use.

This is because it takes time for the active ingredients to build up in your system and exert an impact on hormones (like insulin) and your muscle mass.

Don’t be alarmed with this timing, though, because it’s perfectly normal for any therapy that actually helps you lose weight the right way to take about this long.

If you are undergoing any weight loss therapy which purports to help you lose weight rapidly it will always come at a cost to your metabolic health.

Safe and effective weight loss, on the other hand, allows you to lose weight and keep it off while also improving your overall health.


You aren’t losing weight to get healthy, you are getting healthy to lose weight and this process takes time.

When you are losing weight in a safe and effective way the best way to measure your success is not the scale!

Here’s why:

The scale is a measurement of your total body mass which takes into account many factors including your fat mass, your muscle mass, and your water weight.

What most people who need to lose weight fail to understand is that obesity causes a combination of two things:

A decline in muscle mass and a rise in fat mass.

When you start losing weight correctly, your body will naturally build muscle mass while burning fat mass simultaneously.

When this occurs the scale stays the same (at least initially) and this is perfectly normal!

It’s actually a good thing, too, because muscle mass is much more metabolically active and will help you lose more weight down the road.

At some point, your muscles will reach a steady state and they will no longer grow (unless you are specifically focused on them with strength training).

When this happens, you will start to see the scale move downward.

This process takes around 4-6 weeks which is why using the scale for the first 1-2 months is a very poor metric of your success.

A better tool to assess whether or not what you are doing is working is to use body measurements.

You’ve probably heard the adage that muscle is heavier than fat, right? Even though your total weight will stay the same initially, the size of your body will shrink.

Body measurements provide a safe and easy tool to assess for body fat loss while also taking into account the building of muscle mass.

For best results, take the following measurements when you start and periodically (every 1-2 weeks) as needed:

  • Hips: Find the widest part of your glutes and take the measurement.
  • Chest: Find the widest part of your chest and take the measurement (be mindful of your menstrual cycle which can impact your breast size)
  • Thighs: Find the midpoint between the lower glutes and the back of the knee, and take your measurement here.
  • Waist: Find the narrowest part of your natural waist and take your measurement.
  • Arms: Find the midpoint between your shoulder bone and the elbow of your arm. Take the measurement here.

Berberine 500+ is designed to be taken indefinitely so I recommend using it as long as you need it!

For most people, that will be as long as they are trying to lose weight but it can also be used daily to help with things like blood sugar levels, building muscle mass, and for anti-aging purposes.

You have a couple of different options!

For starters, I would recommend checking out the reviews on all of my products.

I feel transparency is very important to the health of a business and for patient expectations which is why we do not hide or delete reviews.

In other words, you can trust our reviews.

In addition to the reviews, you can also check out some case studies of real patients who have used my weight loss treatments with success.

Here are several that you can check out:

The links above will walk you through everything these patients used to lose weight and keep it off including what type of diet they used, the supplements they took, the medications and hormones that they needed, and much more.

I’ve also included a lot of additional information including how to use hormones, therapies, and other supplements to help with weight loss in my 60-day weight loss program.

My 60-day weight loss program is found inside my weight loss supplement bundle.


You can combine Berberine 500+ with other weight loss supplements or prescription weight loss medications.


Even though they both target insulin resistance, it’s still great to use them together.

Here’s why:

Using berberine with metformin may allow you to keep your dose of performing lower which will reduce negative side effects.

Even though they both target insulin levels, they are working via different mechanisms so you don’t run the risk of competition in that way.

It’s also highly unlikely that the combination will result in low blood sugar (I’ve never seen this happen before).

Berberine 500+ will not break your fast so it is safe to take it while you are in the middle of your fast.

Yes! If you are feeling like you need more assistance then I have multiple resources that can help.

If you want something to help guide you through the weight loss process then my 60-day weight loss program would be a great option.

It contains meal plans, medication guides, a supplement guide, a detox guide, and much more.

It’s built into my weight loss supplement support bundle at no extra charge.

If you are looking for some free information just so you can learn more then I would recommend checking out the many articles I’ve written and videos I’ve produced on the topic of weight loss.

You shouldn’t experience any negative symptoms while taking Berberine 500+. Having said that, sometimes berberine can be a little bit hard on the stomach if it’s taken without food.

If you are experiencing any issues, such as nausea, make sure you take it with food and that should solve the issue!

There is one study that everyone cites that showed that lipoic acid may reduce T4 to T3 conversion. What people don’t often realize is that this study was done in an experimental model of hyperthyroidism so it says nothing about the effects of lipoic acid on hypothyroid states.

In addition, there are far more studies that show that alpha lipoic acid has a positive effect on thyroid function and when all of the research is combined, there are far more net positive studies than negative.

In addition, it’s been my experience that thyroid patients do very well on alpha lipoic acid.

To date, berberine 500+ has been used on thousands of thyroid patients and we have yet to see any issues in T3 levels or thyroid function so this issue appears purely theoretical.

This product does NOT contain Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms, artificial colors, artificial sweeteners, or artificial preservatives.

All product orders to the United States receive free shipping. We ship out within 1 day of your order (unless you order on the weekend) and it takes approximately 1-3 days to reach the destination depending on how far you live away from Arizona.

We offer international shipping as well! You can calculate the price of shipping at the checkout page (we do not mark up the cost of shipping) and currently we ship to all countries.

All of my products come with a 60-day money-back guarantee. I’m confident that my products will work for you but, in case they don’t, for whatever reason, you can return them for a full refund within 60 days. It makes purchasing them a no-brainer!

You can find more information about our return and refund policy by clicking here.

Yep! Every single batch of supplements undergoes third-party testing for heavy metals, pathogens, ingredient profile, and purity. In addition, my products are produced in a GMP-compliant facility in the United States.

Don’t hesitate to reach out! Please email us at and we will do our best to get back to you within a day or so! You can also call us here: (480) 331-9431.

Questions about our quality standards? Please see this article for more information.

Scientific References





















Additional information

Weight 0.25 lbs
Dimensions 2.5 × 2.5 × 5 in

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

**Results may vary.

Customer Reviews

Based on 436 reviews

Good product. I have lost a few pounds and feel it is helping with some of my menopause symptoms as well.

Nadia P.
Getting another bottle!

I had to stop using all the supplements for a month due to being on antibiotics - I just restarted Berberine and I'm hoping to see results while being consistent. For the most part, it doesn't upset my stomach which is super sensitive - that's a major plus for me

Seung h.K.

Burburine make me very bad constipation
I tried couple times
Everytime i try burburine i feel constipated
I can't take it anymore

Frances R.
Thumbs up!

I have been taking this supplement for a several months and my lab value has gone down! It seems to work and highly highly recommend it following Dr. Childs suggestions on the proper way to use it!

Donna R.S.

I’ve been using these products for 1 month and 1/2 and I can tell I’m losing some of my menopause weight gain!! I like to give products 90 days!!

I’m looking forward to the final results!

berberine 500 front bottle image high res
Berberine 500+ | Berberine HCL & ALA Weight Loss Formula
Your Cart
Your cart is emptyReturn to Shop
Calculate Shipping