- After pellet insertion, you cannot adjust your dose if it's too high or too low, meaning you may experience unwanted symptoms for months while waiting for the pellet to dissolve.
- Gels, creams, and injections are equally effective as hormone pellets for delivering bio-identical hormones; choose based on convenience and cost rather than assuming pellets are superior.
- Hormone pellets are best suited for people who travel frequently or struggle with daily compliance, not as a general superior option for all hormone replacement therapy.
- Hormone pellet therapy costs more than other methods due to the procedure involved, and some clinics may push pellets primarily because they are a bigger revenue source.
Are hormone pellets the holy grail of hormone replacement therapy? Do they really provide you with a hands-off, low-maintenance solution to your symptoms?
Not exactly, but there’s a time and place for them to be used.
If you were to ask me, though, I would tell you there are plenty of other, better options available.
Here’s why:
What are Hormone Pellets?
Hormone pellets are simply a way to put a specific amount of hormone into the body through a small procedure.
These pellets are usually created and filled with bio-identical hormones such as progesterone, estradiol, and testosterone.
For men, they typically include testosterone but for women, they may include all 3 or any combination.
These pellets have gained significant traction over the last 10-15 years, but is it all hype or is there something to them?
In general, and for the record, I’m not a huge fan of hormone pellet therapy, but I will walk you through everything you need to know if you are considering this treatment.
There are definitely some people who love their hormone pellets, and who do very well on them, but just because some people do well on them does not mean that everyone should use them.
Hormone Pellets vs Other Hormone Administration Methods
Hormone therapy differs not in the hormone you use (although it can) but primarily in how you put it into your body.
How you take your hormones dramatically impacts the serum levels of your hormones, other sex hormones in your body, your symptoms, and much more.
Because of this, it’s worth exploring all of the options before you jump into hormone pellet therapy.
Hormone pellets require a procedure to be placed, which is unique among all other forms of hormone replacement therapy.
The pellet then dissolves slowly over a period of months, all the while slowly releasing a stable amount of hormone into your bloodstream.
The exact amount of hormone that is placed into each pellet can be adjusted based on the needs of the individual.
In addition, these pellets can also come formulated with multiple hormones.
Taking hormones through the skin, or via injection/pellet therapy, is preferred over oral administration.
Oral administrations have been shown to cause highs and lows in hormone levels in your serum (2) and may dramatically increase other hormones such as SHBG.
So, pellets are favored in that way.
But how do they compare to creams/gels/shots?
In terms of efficacy, pellets are no more effective than a gel/cream or injection in theory.
Basically, as long as you don’t take your hormones by mouth you should be good to go.
The choice of which type of hormone method you decide to use largely depends on your preferences.
With this in mind, it’s helpful to have a full understanding of the pros and cons of pellet therapy so you can help make the decision for yourself.
Pros & Cons of Hormone Pellets
Every procedure, therapy, or medication comes with a list of potential benefits and potential side effects.
You must weigh the pros and cons to determine if the procedure is right for you!
In some instances, your doctor may have an incentive to push you in one direction (usually due to reimbursement) even though there are other options available to you.
Make sure you understand these pros and cons before you get hormone pellet therapy.
Pros
#1. Set it and forget it approach
Perhaps the most important benefit of using hormone pellets is what I refer to as the “set it and forget it approach”.
This approach stems from the fact that hormone pellets are relatively hands-off in terms of patient compliance.
You get the procedure done in a short visit and then the pellet dumps hormones into your body over the next 3-4 months.
There’s usually a peak hormone rise around the first 1 month and a drop thereafter (4).
Most people tend to start feeling their symptoms return around 3-4 months (some shorter or longer) which drives them back into the office to get another pellet.
This is great for some patients, especially if you find it difficult to apply gels/creams on a daily basis due to a heavy travel schedule or other conflicts.
This is also another option if you can’t stand to be injected on a weekly/biweekly basis (for hormones like testosterone).
But, if you don’t mind applying your hormones to your skin on a daily basis, then this benefit may not apply to you.
#2. Contains bio-identical hormones (superior when compared to pharmaceutical and synthetic hormones)
Hormone pellets also have the benefit of containing bio-identical hormones.
Whenever you look for hormone replacement therapy, of any kind, make sure you are using bio-identical hormones.
You’ll know you are receiving these hormones because the name of the hormone your body creates is the same as the hormone you should be taking.
For instance:
If you want to take estrogen then look for a medication that contains estradiol.
If you want to take progesterone then look for a medication that contains progesterone USP.
Synthetic formulations of estrogen (6) include Ethinyl estradiol, esterified estrogens, conjugated equine estrogens, and so on.
Synthetic formulations of progesterone (7) include medroxyprogesterone acetate, norethindrone acetate, norethindrone, norgestrel, norgestimate, levonorgestrel, desogestrel, and megestrol.
Whenever possible, stick to hormones that are identical to what your body produces naturally!
#3. A stable stream of hormone delivery
The pellet delivery system is designed to provide a steady stream of hormones directly into your body.
It is deposited into the subcutaneous tissue, which is relatively avascular compared to other tissues (meaning it has fewer blood vessels) which reduces the rate at which it is absorbed.
This allows for your body to break down the pellet based on the surface area which supplies a relatively even hormone dose directly into your body and tissues over several months.
Cons
#1. Requires a small surgical procedure for each visit
The fact that hormone pellet therapy requires a small incision is something that should be considered by all patients.
This procedure will require an office visit with a doctor and time on your part.
You can compare this to simply calling in for a refill of your prescriptions which can easily be done over the phone or through an assistant.
#2. More expensive when compared to other methods
Hormone pellets also tend to be more expensive when compared to other forms of hormone replacement therapy.
Anytime your doctor has to do a procedure, spends extra time with a patient, or has to mitigate an increased risk of infection, there will always be higher costs involved.
The actual hormones themselves are quite cheap.
The price that you pay for the pellet tends to come from the formulation of the pellet, the time it takes to implant it, and so on.
If you are trying to save money, then sticking to the basic hormones in gels/creams may be a cheaper alternative.
Some hormone locations tend to shuttle people into hormone pellet insertion because it is a big money maker for the clinic.
Do your best to avoid clinics like these, especially if you feel that you are being pushed into something you don’t want to do.
#3. Increased risk of pain/infection at the insertion site
Anytime the skin is entered, either through injection or otherwise, there is a small risk of infection or bleeding after the procedure.
With infection rates around less than 1% of all procedures (10), there’s probably around a 1 in 150-200 chance that your hormone pellet therapy may become infected or have complications.
This risk is low but can be real if you plan to get the pellet 3-4x per year.
#4. Inability to alter or adjust dosing after implantation
One of the biggest problems with hormone pellet therapy, from my perspective, is the fact that you can’t alter dosing after you implant it.
Once the pellet is implanted you will be getting the hormone that you were prescribed for several months whether it’s the right dose for you or not.
This can be a problem because it’s quite rare that doctors get hormone dosing right on the first try.
Adjusting hormone dosing is a regular part of treating patients with hormone imbalances and it can take months to get everything just right.
If you put in a pellet that contains too much hormone then you will experience the side effects associated with hormone excess for several months.
On the other hand, it’s also possible to put in an insufficient dose and have the pellet be ineffective.
It’s far easier to simply add to your dosing or take away from your dosing when using gels and creams.
Side Effects
Side effects from hormone pellets tend to stem from the DOSE and WHICH hormones they contain.
So, it’s not as if all hormone pellets will give you the same symptoms (or benefits) because that largely depends on your prescribing physician.
There are some potentially negative side effects that are unique to hormone pellets and these are included below:
- The potential risk for infection at the insertion site
- Potential for Bumps/nodules at the insertion site
- Potential for overdosing hormone (if dosing is done inaccurately)
- Potential for underdosing hormone (if dosing is done inaccurately)
- Potential for weight gain (if dosing is done inaccurately)
- Potential for breast tenderness, menstrual bleeding, hot flashes, and weight gain (specifically if dosing of estrogen is too high)
- Potential for acne, irritability, weight gain, facial hair, and dramatic rise in libido (specifically if testosterone dose is too high)
- Potential for water retention, depression, dizziness, and weight gain (specifically if the progesterone dose is too high)
These side effects largely depend on the hormones you are using, the dose they are formulated with, and various other factors such as how you tolerate them.
Limitations & Who Should Use Hormone Pellets
Hormone pellets certainly aren’t for everyone, but I’ve combined a list of patients who tend to do well on this type of hormone therapy below:
- Those who desire the “set it and forget it approach”
- Those who travel frequently or who frequently forget to use gels/creams
- Those who have trouble remembering to apply their hormones on a daily basis
- Those who already know what their “dose” is and just want a more convenient approach
- Those who have better symptomatic control with pellets over gels/creams
- Those who would rather not take the risk of exposing family members to hormones through close touch, etc.
If you do not fit within these parameters then it may be wise to seek out (at least initially) other ways to take your bio-identical hormones such as the transdermal route.
Do Hormone Pellets Cause Weight Gain or Weight Loss?
Many patients get hormone therapy to fix a specific problem and one of the problems they are looking to fix is often their weight.
There is no easy answer to this question because it really depends on if your doctor is able to dose your hormones accurately through pellet therapy.
If the dose is correct then you may expect to see an improvement in your symptoms and you may see some weight loss.
If your dosing is incorrect, either too much or too low, then you may see the opposite effect and you may actually see weight gain (11).
This is why you see conflicting stories about people who state they either gained weight on hormone pellets or lost it.
It’s not the pellet therapy itself but rather the dose of the hormones.
But remember:
The dose can be achieved through other means, such as gels or creams.
The bottom line?
Don’t count on hormone pellets as a primary weight-loss tool, instead just be happy if they happen to help you with weight loss along the way.
There are much better, and more targeted ways, to lose weight which you can read about here.
Final Thoughts
Hormone pellets are one of many ways to provide your body with a steady supply of specific bio-identical hormones.
Like other therapies in medicine, there are specific pros and cons to using this type of delivery system.
While pellets may provide you with decreased maintenance (in terms of how often you have to “apply” hormone), they come with an increased risk of other overdosing hormones and other side effects such as infection.
Before you get a hormone pellet implanted into your body make sure you fully and completely understand the potential risks and benefits involved.
Now I want to hear from you:
Have you had hormone pellet therapy?
Are you thinking about this type of therapy over other options?
Did it work for you? Why or why not?
Leave your comments below!
Scientific References
#1. https://www.ncbi.nlm.nih.gov/pubmed/11678837
#2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897322/
#3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599554/
#4. https://www.ncbi.nlm.nih.gov/pubmed/2115044
#5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127562/
#6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469890/
#7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960754/
#8. https://www.ncbi.nlm.nih.gov/pubmed/22403285
#9. https://www.ncbi.nlm.nih.gov/pubmed/25961202
#10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812878/
#11. https://www.ncbi.nlm.nih.gov/pubmed/23924704
Hi Dr. Childs,
I have read 2 blogs saying that hormone pellet therapy can slow down the progression of a heart attack. I just want to find out if that is true. Any help is much appreciated. Thank you.
Hi Dan,
Yes, I believe there is definitely truth to that statement. Hormones such as testosterone in men and estrogen/progesterone in women do seem to play a cardioprotective role and their decline seems to be closely associated with an increase in heart disease. It’s not the pellet therapy that is doing this, however, it’s the hormones and those can be taken via any route.
What are the symptoms after stopping my bhrt with pellets? I am spotting and want it to stop hysteroscopy shows everything normal. Why I’m I still spotting? My 3rd insert that won’t happen is July 28, 2019. What should I expect after stopping?
I’d really like to try the hormone pellets for testosterone therapy. I’m a transman without a uterus and I have a good idea of what hormone levels are right for me. I’ve been doing my own injections for over 5 years. I hate dealing with the constant “testosterone shortages” which leave me without an ability to get testosterone for weeks. The shortages usually involve the injectable testosterone cypionate but other forms like gel and patches are too expensive or don’t offer high enough dosages for trans men. I know this sort of thing happens to trans women with injectable estrogen as well. Even if we are able to get an alternative we still have to make an appointment and get a new prescription so by the time we get our medicine things are not going well.
I also have mitochondrial disease, autism, and diverticulosis. Being without testosterone exacerbates my stomach cramps, insomnia, and my Mito symptoms and it wreaks havoc on my mental health. It’s hard to deal with all of my health issues especially being bed ridden and isolated. When you add a sudden lack of hormones my life gets unbearable.
The idea of getting a long lasting alternative administration is very attractive to me. I’m also experiencing some severe muscle cramping and twitching every time I do my injections (due to the Mito) and I would love to cut that out of my life.
My fear is that the pellets will be denied to me because I am transgender. It seems like many medical professionals see HRT as a luxury item that is purely cosmetic. I’m a complete mess health wise but I’m not hurting in the looks department. I’m already devastatingly handsome folks. I need testosterone for other reasons like bone density, digestive regulation, immune response, etc.
Have you heard about this treatment working for trans folk?
Hi Max,
Unfortunately, I don’t have any experience in that area so I can’t really give advice on that topic. I’m not sure a physician would refuse to give it to you though if you explained your situation.
The only issue I could see is the labeled gender on your blood test results as that would influence the reference ranges. If those ranges showed the female testosterone ranges but you were receiving the male dose then it would appear that you severely overdosed and that could be an issue for the physician but as long as it’s labeled appropriately then I don’t think it would be an issue.
Pellets would appear to be a reasonable option, as would getting your testosterone from a compounding pharmacy as they tend to have a more stable stock compared to the big box pharmacies.
Hi
I have been on the pallets for the last 2 years with Testosterone only. I am 47 years old and I started with the pallets because my doctor tested and it was Testosterone 10 only.
The doctor said my low libido, tiredness was caused because of the low Testosterone. I am still having my regular period. I was also diagnosed with Hypothyroidism and I am taking Naturetroyd.
The beginning of the treatment was awesome but I gained weight and I have this rage going on, insomnia, anxiety.
It has been almost 4 months since my last pallet insertion and I started to have all the horrible side effects that I think is due to the withdraw of not having the hormone ( normally I have to go back every 3 months).
It feels like a drug that my body needs otherwise I start to feel all these horrible symptoms.
How do I stop the pallets? Without going crazy? Do you think my body can go back to normal? I prefer to feel low energy than be crazy like I am feeling right now. Thank you.
For the first time in my life, I understood what it meant to rage. I got very angry and my cortisol levels remained elevated for weeks. I was afraid of myself until I was able to get another pellet inserted. That was my last pellet because with the last insertion came hair loss. I was able to control myself better when the last pellet wore off because I was shaken over the extensive hair loss and was afraid a rise in cortisol levels would exacerbate the situation. Good luck!
Hi Dr. Childs,
I’m 37 and had a radical hysterectomy in 2015 due to endometriosis (so they took everything, even the lymph nodes). Since then my health has gone downhill. Gained 30lbs despite being vegan and on a healthy diet (low oil, low sugar, low salt, moderate carb, healthy fats) and exercise regimen. My calcium shot up to 11, vitamin D incredibly low, and a nodule on my thyroid, all of which have been regularly monitored over the past 2 years without any action or plan by my Drs. I recently went to a Functional Dr that did a full bloodwork panel including hormones. Results showed there were obviously undetectable amounts of estrogen, barely any testosterone, extremely low functioning thyroid, total cholesterol 253 (my good cholesterol was 72 which I was told was good), calcium was 11.2, and vitamin D was still low. It was recommended to start on BioTe for both estrogen and T, take Armour thyroid (even though it’s not vegan), and do vitamin D. BioTe was positioned as potentially having the ability to reduce the cholesterol levels based on the fact that the body’s hormone-producing glands use cholesterol to make hormones such as estrogen, testosterone, and cortisol. Since my body isn’t producing much or really any hormones at all, I would think that my body was maybe trying to produce additional cholesterol in an effort to gain hormones by way of conversion (from cholesterol to hormone via gland conversion), since my diet is pretty much cholesterol-free. I have pretty much felt like total garbage since the hysterectomy, and BioTe seems like it’s worth a shot. The current plan of waiting and monitoring (from 3 different Drs) is feeling a little stale at this point and I just want to be proactive and not end up having another surgery as a result of playing the waiting game again (12 years of just brushing off my endo and not doing anything after a miscarriage, chocolate cyst, and violent bouts of sickness). Do you think BioTe pellets tailored by my doc at 20% below the program recommended dosage sounds like a workable option based on my past history?
I started on the Bio-identical Testosterone pellet 14 months ago for peri-menopause symptoms. The daily dosage was inconsistent and wore off around ten weeks so my dosage was too high. High levels of testosterone in women are linked to a type of breast cancer. I had some concerning withdrawal symptoms when the testosterone levels waned. My hair started to fall out 4 weeks after my last injection & I suffered psychological trauma from that. PRP saved my hair, but it cost about 4k and it hurts. I also found out that women are not to take testosterone alone without progesterone – I didn’t know that, and I went to an OBGYN!
Hi Katherine,
It’s definitely possible to take testosterone without progesterone so I’m not sure where you heard that but I want to clear the record for anyone who may be reading this. Problems related to testosterone in women are almost always related to dose, not the hormone itself.
Hi Dr. Childs, I am a 50-year-old woman, and I have been doing the Testosterone pellets since June of 2018. My initial blood test showed my estrogen levels were super high but my testosterone levels, thyroid, Vitamin D were all dangerously low. Ever since taking the Testosterone pellet, Armour Thyroid, Iodine, Dim, and Vitamin D, I have had great success with my energy levels, strength, libido, mood, more focus. I did gain about 15 pounds though, but didn’t care as much because I felt so good (my weight, to begin with, was only 120 lbs and now I’m 135 lbs, 5’ 6” tall) My Dr has been monitoring my bloodwork and after my 4th pellet he noticed my cholesterol is dangerously high. Both my OBGYN and my Primary think the high cholesterol is linked to the BioTe Testosterone pellets. They are telling me to discontinue use of the pellets but I’m super afraid to stop, not knowing if I will have withdrawal if my panic attacks will come back along with depression. Alzheimer’s runs in my family which is another reason I like the T pellets, however, my doctors say high cholesterol increases dementia and possibly Alzheimer’s. I am wondering if I should just go on a statin drug and continue the pellets or try a different type of hormone therapy. I was told that having super high levels of estrogen with very low levels of Testosterone can put me at risk of getting breast or ovarian cancer, so I’m terrified of stopping the Testosterone. Any advice here as to what I should do?
Also, have you heard of any correlation between drinking coffee that has high levels of Cafestol (found in Nespresso brand pods that are used for their coffee maker) and high cholesterol? Out of nowhere, I started drinking coffee last winter, mainly one cup per day (with almond milk) from my brand new espresso machine. When I got the call about my high cholesterol levels I was examining the foods I had been eating. The only change was my new love for coffee and the Testosterone pellets. And I have read online that Cafestol can cause high cholesterol and it’s prevalent in Coffee pods. I eat a very healthy diet otherwise. Just wondering if anything else could be causing the high cholesterol so I can continue getting the Testosterone?
I have read that about coffee, too. My cholesterol was always normal until I started the paleo/primal diet. Then it was elevated, but my hdl was, too, so I didn’t worry about it. But after I switched to French press coffee, it really went up! Paper filters are supposed to remove much of the cafestol. On the other hand, you’re removing some of the health benefits, too! I wouldn’t think that espresso machines would do the same because the grounds aren’t stewing in the water, but maybe there’s a lot of cafestol in the crema made by good espresso machines.
Incidentally, did you know that weightlifting lowers cholesterol? If you look around you can find clinical studies showing it’s effectiveness in removing cholesterol from the blood even after high fat meals. My doctor did tell me to weight lift at least three times a week, and do push ups and other weight bearing exercises daily while on testosterone, I think to help my bones, but maybe cholesterol, too? I would hate to quit testosterone, despite the weight gain, because my anxiety is gone, and I really thought I was getting early Alzheimer’s because of how bad my memory loss was. Maybe you can use the cream while they sort out your bloodwork?
I hope you are taking progesterone to balance the high estrogen!
Hi Dr. Childs,
I had one ovary/phil. tube removed at 17 (cyst that ruptured). Then radical hysterectomy at 32. I took Premarin for 18 years.
At age 55, due to osteopenia, I started my Biotne Pellet injections on May 7th. I then got a boost of testosterone on June 16th. I got my 2nd round on August 7th. I am now experiencing dizziness, headaches, nausea, and breast soreness that shoots under my armpits. Is this normal???!! I am not going to get any more pellet injections. Will I experience withdrawal? Help!! I do not know what to do…
Hi Dr. Child,
I have been on Estrogen and Testosterone Pellets for a little over a year. My estrogen levels were totally depleted as well as my testosterone. I had absolutely no desire for sex and now I feel like I am 25 again. I do like the effects of the pellets but here lately since my doctor lowered my dose, I’m finding myself having to go back more frequently. I saw in a few of your other post that you mention Creams/gels. Will that give the same effects as the pellets? Do I need a prescription for them? Can you recommend some brands if over the counter?
I started the testosterone pellets a year ago in July. I had one good month of great libido and other than that it was crap. I don’t believe he gave me anything other than testosterone and something so I didn’t grow hair. I started out at 150 lbs before pellets and now am at 168 and cannot lose weight to save my life. He put me on anavar to slim me down and after 4 weeks and 12 lbs gained I stopped that. He then wanted me to try aderal as he said that would help with my anxiety. I read up on that and never took it. He then wanted to try me on something for thyroid as it was a appetite suppressant and my T3 and T4 were fine so didn’t do that either. Needless to say I have stopped going to him and was due for pellets end of October and now I’m just exhausted all the time. I feel that he took me for a ride and it was all about putting money in his pocket. Not sure what to do about the weight I was a sized 8 and now a 12-14. I started cross fit about 4 weeks ago so we’ll see.
Hi Michelle,
This sort of story is one of the main reasons I recommend against hormone pellet therapy. I just think there are better, cheaper, and more effective hormone management strategies.
I was going to look into pellet, i think i will cancel my appointment now that i have read some of these and stick to my np thyroid.
Hi Linda,
You can still use hormones but I would NOT recommend using the pellet as a mode of delivery. I think most of the comments here speak to why.
Go get the pellets!!! If you have a good Dr. that monitors you everything will be ok. Many more women and men are enjoying the benefits compared to the few complaints on here. Creams/ gels/ injections actually can cost the same as the pellets and I can tell you NO one administers the above the way they are suppose to. Do yourself a favor – try them.
Hi Ray,
Please point us to the many more women and men who are enjoying the benefits of the pellets. I see far more people complain of pellets than those who do well on them. When you factor this with the cost of the procedure, risks associated with the procedure, variability in dosing, inability to alter the dosing, and more, getting the pellets becomes less and less attractive.
Well if the Dr. is properly trained and does followup blood works after the initial and before every dosing you should have no issues with the pellets. Infections are very rare. Even in the comments above less than 1% of your small sample. In our area $300 is the cost for women and $700 for men.
Compounding creams and injections aren’t reliable and are just as expensive and most are synthetically made. The dangers of transmission to the opposite sex and children- the staining of clothes…. far more issues with creams and 90% of the time they aren’t strong enough. Plus who wants to put extra cream in their vagina everyday? Messy to say the least.
Injections cause the peaks and valleys every week- not good for you. Plus they are synthetic.
I think you are doing a disservice not recommending pellets. It’s up to the patient to find a qualified Dr that administers and keeps up to date and is not just trying to make a fast buck. I also recommend that women use female gynecologist and BHRT Dr.’s as they are more sensitive and familiar with a women’s perspective and needs.
While not exactly on topic but of concern with breast cancer- why don’t you recommend Thermography of the breast instead of cancer causing mammograms? It can detect cancer up to 7 years earlier than mammograms. A well informed patient can make educated decisions about their health care- unfortunately too many don’t stand up for themselves and are taken advantage of.
I agree with your other issues on your website of closely monitoring your T3 and T4 levels of your thyroid. Many of the above complaints are probably more related to that rather than effects of the pellets.
The idea that serum blood tests of hormones are accurate and can be used as predictors of the necessary hormone dose required is proven to be false. We know that this is the case, which is why we have other methods of hormone testing such as urinary and salivary, which means that there is some percentage of people who will get underdosed or overdosed with pellets guaranteed. You could get lucky and not be one of those people or you could be unlucky and be one of those people. If you are unlucky then you just have to deal with being overdosed for weeks to months until it is metabolized.
In regards to synthetic hormones, all sex hormones are synthetic and that’s not the issue. The issue is whether or not they are bio-identical and they all can be. To suggest that hormone pellets are “natural” and creams/injections are “synthetic” is disingenuous and simply not true. I only ever recommend bio-identical hormones regardless of the application.
As I stated before, the peaks and valleys found with hormone injections more closely mimic the daily variation that occurs when your own body produces sex hormones. Pellets provide a constant diffusion of hormone into the surrounding system which slowly falls over time based on the gradient of hormone in the pellet and in the surrounding tissue.
You must not be aware of daily subcutaneous injections because if you were you would understand that no other method of hormone administration more closely approximates daily variations in a healthy hormone levels. You may not want to give yourself an injection every day but if you cared about that then you would immediately switch to this method. Your statements above assume once a week injections which is not how I recommend using TRT.
At the end of the day, people can do whatever they want with their health, I’m just giving my opinion and my opinion stands that hormone pellets provide no more benefit than other forms of HRT and they come with considerably more side effects and dangers.
I have no comment on thermography here because that’s not what this article is about.
I had blood work done and my results revealed I had low testosterone. So I went in for my 1st pellet insertion a couple months ago. I felt great the 1st couple weeks after and then started to feel off again. Doctor had me get blood work done again and then come back in for second pellet insert. My blood work showed my levels were all improved and pretty good, but I was still frustrated why I was feeling off again. They told me your levels can drop/fluctuate quickly and then they gave me another pellet insert. This last time I haven’t felt any improvement and my anxiety, depression, ext has been pretty bad (had to get back on medication) and I’m now on month to after last insert. Could this be as a the result from the pellet?
Hi,
I had a hysterectomy about 10 years ago but I still have my ovaries. about a year and a half ago my doctor recommended Biote Pellets. The doctor did a full blood work. Said my Testosterone was really low so she inserted 3 testosterone pellets. It took a bit for it to fully kick in. It is wonderful. I’m not as crabby with everyone. I don’t have hot flashes. I sleep at night like a baby. My sex drive is back. The downside I have developed Osteoarthritis. Ive gained close to 70 pounds. I’m miserable. I try to do my Biote injection every 4 months. My doctor just informed me they cant do the injection because the company of Biote changed their rules and nurse practitioners can not administer it only certified MD Doctors. Now I’m having side effects of coming off of it. It is awful. I really don’t know if i would suggest anyone to try Biote.
Hi
I have been taking hormone pellets for 10 years (bioTE) I have been happy no problems Until my insertion 4 months ago I started having terrible pain in my legs specially in the knee and ankles (at night) I brought it to my doctors attention he didn’t think it had anything to do with the pellets. It eventually went away. Fine and good until this last round of pellets after three days I started having the same symptoms in my legs at bedtime have you any suggestions
my Gyn is not buying into the pellets causing this. Do you have any suggestions
I had a testosterone pellet placed a little over a year ago to balance my hormones. Almost immediately I began to gain weight. I am 5’52”,I went went from 130 lbs to 145 lbs. I eat healthy. I limit my carbs. I practice intermittent fast daily. No matter what I do I have not been able to loose any weight. I am afraid of diabetes and hypertension because they are prevalent on both sides of my family. My only saving grace right now is that I am a yoga teacher and I practice yoga daily.
Hi Ellie,
I would take a look at your menopausal status (are you post menopausal or peri menopausal) as well as your thyroid status. Either or both of these could explain your inability to lose weight.
I’ve been on pellets for 3 years. Did really well. I love the pellets as far as relieving symptoms and convenience. Do not like the weight gain. It’s really become a problem since last year. My weight has never been a problem, but now- I don’t even have to eat something for my weight to go up… just looking at it makes me gain. Ugh!!
Considering stopping pellets. What recommendation can you make about transitioning back to creams or injections?
Good Afternoon Dr. Childs,
I had the pellets implanted 20 March 20. I have since gain 22lbs, tired all the time, I don’t sleep well and I hate having to take the pills. Why advertise the pellets as a no fuss product when pills are required to be taken daily? I get up at 0500to take the Armor Thyroid, wait required four hours to eat anything, which now delays my workout times. I would like to eat some small portion of food before I workout. Half the time I forget to take the progesterone that needs to be taken before bed. I’m less alert now, I feel it was a waste of money.
Dr. Westin
I have done pellets for 2.5 yrs now and was doing great until about 4 months ago when i started bleeding frequently (and heavy at times). We adjusted the progesterone dose multiple times. I had an ablation and 6 weeks after that it returned! I have let my last pellet “wear off” and now lack of sleep; lack of drive; hot flashes all returned. I also take Thyroid Armor for low T3. I want to try the pellets again but really do not want to start the bleeding again. I suspect that may happen -correct? MD offered me a hysterectomy. I have read there is a strong correlation with BHRT by pellets and hysterectomies. Can the Estradiol be lowered to prevent bleeding or will that help? Will the same effects happen with cream BHRT? Would like some input.
Hi Trish,
In general, it’s quite easy to manage bleeding when using BHRT. It’s just a matter of adjusting the progesterone and estradiol dose. Pellets make that more difficult, obviously, because once they are in you can’t adjust them (which is one of the main reasons why I don’t recommend using them).
Dr.Childs, I have been using BioTe hormone replacement therapy for many years. I changed doctors a couple of years ago & she used that type as well until recently. I found out that she is using pellets from Asteria now. I’ve tried to research Asteria to see if their pellets are bio-identical & have found little about their product. Do you know if Asteria’s pellets are bio-identical? Also, have you seen any correlation to breast cancer & this type of HRT in any of your research? Thank you!
I had an estrogen pellet inserted in January. I started noticing a burning sensation in my vagina. By the first of May, it grew worse. I made an appointment with my doctor. (I was also having spotting every day). My doctor did a vaginal ultrasound and found a polyp in my uterus . I am having surgery to remove the polyp. I will NEVER put anything in my body which i cannot remove!!
Linda
I have a Dr appt in Thursday to discuss the pellets. Is there a higher risk of getting breast cancer with the pellets? I was using a gel form of HRT Along with progesterone until my Dr. did a risk assessment and my chances of getting breast cancer are at almost 40% due to dense breasts and family history.
Ive had SottoPelle bio identical hormone therapy since 2008 and have always done very well with it. Never had an infection or other problems with it. But, I have always discussed with the doctor inserting them, I have had 2 different doctors during this time, and I have always asked for the minimum dose possible. This has worked very well for me. I also have him implant only testosterone, and if I get any symptoms, the lowest dose of Estradiol, which is implanted every year or so. I believe what has worked the best for me is being so conservative in my approach to SottoPelle.
I am currently on BIO TE hormone Replacement Injections. I was a mess with a toxic case of vaginal atrophy. Sex was painful, and severe thinning of the vaginal lining. Diagnosed with Non-Hodgkins Lymphoma Cancer through me into early menopause. Chemo killed my ovaries and the Hot Flashes were just unbearable after ten years. I tried the Mona Lisa Touch which helped me totally. I am on my 6th insertion and I have done amazing. Initially, my orgasms were intense, and by breast nipples became very tender. Through blood work, my dosing had to be adjusted, by the third injection I felt totally amazing and normal. My libido has improved and no more tender breast. I have a fantastic Dr who monitors me closely.
Hi Dr. childs,
I am 49 years old, this year I started SottoPellet bio-identical hormone therapy in May. I love the pellets, they have helped me get rid of my anxiety as well as provide me energy. In July my feet swelled up and continued into August. In seeing a regular physician, he did not feel that the two were related, as symptoms, normally happen within the first two weeks. After my husband read your blag he has concerns that this could possibly be a side effect. Can you please give me your thoughts on this?
I have been struggling with losing weight, even before I started taking the bio-identical. In reading a lot of the blags above, I see that many individuals are gaining weight. Is there something that you can recommend, that we can use to assist with the weight gain?
I’ve been using hormone pellets for almost 2 years and have lost 70lbs. I kept gaining weight using the creams and had zero energy. I probably dropped 35lbs in the first couple of months using the pellets. It’s been a godsend for me. Also, sex drive is off the charts- like being in my 20s or 30s again- I’m 57. My husband goes as well and uses testosterone injections twice a week. My Dr is a very knowledgeable anti aging dr, and very good with HRT.
I couldn’t be happier with hormone pellets. Many friends that have gone, have also had the same or better results.
I was so informed by reading Dr Childs correspondence. I had my first BioTE pellet in March 2020 and felt great. I had the second insertion July. I am so miserable with hair loss , weight loss (92 lbs) and extreme thirst. I am taking 1 mg Finasteride to counteract the DHT (from testosterone). I read the information on Finasteride which says women should not take it . I am so concerned most about my hair. Any comments. Ali on 10/11/20. Thank you so much
My Sottopelle doc has me on 50mg spironolactone to block the dht. Hope that helps!
I am TRYING to find an answer about pellets and high blood pressure. Several years ago, I was prescribed Premarin. Never did anything for me and quit taking them because my blood pressure was creeping up. Have been on pellets for 2.5 years. Gained about 30 lbs. since being on it. Now my blood pressure is unstable. Tried a few drugs and lifestyle changes. I am at my wit’s end. Could the pellets be the reason? Thank you !
52, hypothyroid, hysterectomy with breast cancer treatment at 42, very fit have always worked out 5-6 days a week with weight training and cardio. Average daily calories 1300-1500 weight shifts between 125-130, 5’4″.
Started testosterone pellet therapy in December 2020. One month in (Jan) labs are: testosterone 216, free t3 and t4 are on low end of normal, cholesterol is high (never had that before) and I’ve gained 7 pounds (fat around my stomach mostly but also legs and butt). My clothes don’t fit!!
It’s disgusting. Nothing else has changed in my life but adding this to try and mitigate some of the lingering menopausal symptoms from hysterectomy.
I can’t wait for it to be out of my system! It’s almost impossible for me to lose weight once I put it on which is why I’ve been so meticulous about not putting it on since entering menopause at 42. Now, every week I weigh myself and I’m up ANOTHER POUND or two. Unbelievable.
I’m so aggravated that this was never discussed as a potential side effect, and even while searching online it isn’t given much attention.
Thanks for posting!
Cut your carbs to less than 30 grams a day and increase your protein intake. Keto will strip that 7 lbs off you in 2 months tops.
Hello Dr. Westin,
I may be different than most of your other posters. I am 81 years of age. Most people think I am closer to 60 to 65. I used to have pellets about 13 or 14 years ago. I had no idea what questions to ask nor what would happen when I took the pellets. The reason I started taking them was because I had become so fatigued, tired, irritable, not sleeping well and lots of headaches. I was normally very active. Someone recommended that I try the pellets. They worked and quickly. I instantly felt better, but over the course of several years using them I was slowly gaining weight, lots of facial hair and loosing hair on my head. I felt that I was receiving way too much testosterone and not enough estrogen. I was told by the clinic that I was wrong and they would not listen to my concerns. I finally decided to discontinue the pellets. I really loved the way they made me feel. I don’t think that my age should keep me from either getting pellets or creams or gels. What do you think?
My husband and I are mid 50s and felt like we were just going through the motions of life. Somewhat content and settled, married roommates is how we described ourselves. Menopause hit me at 40 and by 48 there was no more sex because of the pain and mutual lack of desire. We did the BioTE pellets together 3 months ago. Yes the first two weeks were moody, but we were warned. Yes we both puffed up a bit from water retention but we were warned. Our Dr did not immediately out us on the levels that are recommended, she is easing us into it. Our zest for life has returned. No longer sitting around in screens, bored….we are going going going all day. Projects are being completed, long ignored tasks (garage cleaning) have been tackled. Our sex life is freaking awesome. We spend time talking, touching, just being together. Both of us have amazing attitudes and have fallen in love with each other again. The unseen bonus is the protection against diseases that run in both of our families. I will do this therapy until the day I die. We feel like we are in our 20s again as far as energy level and positivity. I would rather live a shorter life like this than a long one the way we were, so even if there were dangers instead of only benefits we would still do it. I think it important for couple to make this journey together, not singularly.
I had testosterone pellets implanted and was prescribed 200mg of progesterone at the beginning of Feb 2021. I have not been able to sleep. Up for 2 days. My blood pressure was through the roof. On norvasc 5 mg now. Sleep apnea is horrible and gained fluid. I felt like I was poisoned. Still waiting for the pellets to wear off. In the ER twice. Horrible roller coaster ride.
My doctor talked me into trying the BioTE pellets in November 2020. I had been using bio identical cream for several years prior. I’m post menopausal, mid-sixties. I’m on my third pellet insertion and am due again in November. Over the past year or so I have developed fibrous tissue in my breasts and discomfort right below my breasts to the point that I can’t stand to wear a bra all day. After reading all these comments I’m wondering if this could be a side effect of the pellets. Have you heard of anyone else experiencing this?
Hi Shauna,
Do you have fibrocystic breast disease? It would be hard to give more information without identifying what you are dealing with.
I am 48 years old and suffered from PCOS my entire life. I had a complete hysterectomy at 47 due to scar tissue, uterine fibroid tumors, multiple cysts, ect. Best decision my doctor and I made! I have tried the patch and the cream. It seems my skin will not absorb any hormones in this manner. He has recommended the pellets beginning next month. My estrogen level is currently at 0. I am already overweight and do not want to gain any more. Is there anything I can do/start before the pellets to help in this manner? Anything I need to prepare for, since I will be going from 0-60 on the hormone spectrum? LOL
Hi Angela,
I don’t really recommend using the pellets for the reasons listed in this article.
I know of 4 women that used pellets and all developed breast cancer. One of the four is unfortunately no longer alive.
Hi Connie,
That’s very unfortunate indeed!
I tried the Biote testosterone pellets and Estrogen pellets in January 2019. I had no idea that they were going to change my body forever. I ended up still being sensitive to the effects of the testosterone. It’s 2022 and I still feel the water retention and I am still bulky. I packed on weight and add the water retention it’s very uncomfortable. I have IBS and sometimes I feel like the water retention is in my stomach and I can’t eat I’m too bloated. I think the dr gave me too high of a dose, I developed masculine attributes such as change in voice, facial hair, irritability and my face changed in appearance. I also developed a sensitivity to lifting weights, I would have bouts of diarrhea after lifting heavy weight. I can’t believe I still feel have the water retention even though my body is less bulky with less muscle now. I’m back on just estrogen and I’m trying to counteract with what I feel is the remnants of the testosterone. I wish I would have just got them surgical removed. DO NOT RECOMMEND!
Hi Yvonne,
Thanks for sharing and sorry to hear about your experience. Hopefully, you will be able to get back to your previous normal soon.
Hello! I’d have to say Hormone pelleting is a total game changer for me. Total hysterectomy at age 32 (or bleed to death) & I could note tolerate oral Estradiol. I went YEARS with nothing. My mood got so bad I couldn’t stand to be around myself. Long story short…I was introduced to the pellets by my best friend in another State, did some research where I live & had my first pelleting March 2022. #TOTALGAMECHANGER
YES, I gained weight with the first pelleting. My body had no idea what hit it after years of being so depleted I’m sure it was in total disarray. 2nd pelleting ❤️! No weight gain & I lost what I had gained. My mood is incredible, my appetite is much improved & I actually sleep all night. And yes, my libido has gone through the roof! But I’m not complaining. My body was in hell for years & I didn’t know how or what to do. Nothing will stop me from continuing the pellets. Without them, I’m not the same person & I have no intention going back to the miserable wench I once was. If that means packing a few extra pounds, I’ll do it & be overjoyed about it.
Please remember, there is NO quick fix. Be gentle to your body during menopause. Your body carried you through a lot up until this point. Give your body what it needs, & be patient.
Deb (55 yrs old)
I am 51 and post-menopausal. I have had two “regular” insertions of BioTe and one “boost”. Just did my blood work follow up, and my Testosterone is at 277, Estradiol is at 61.9. I also take 200mg Progesterone orally QD at night, and take BioTe DIM in the morning. I still have ZERO libido. I have maybe noticed a slight increase is facial fuzz, and have had one or two pimples pop up over the last 6 weeks since my second “regular” insertion. My doctor says I am a high metabolizer. My first insertion was June 23, 2022. Shouldn’t I be feeling some change in my libido by now?
Hi Alisha,
If your libido issue was related to your hormones, yes. There are many causes of low libido, though, outside of just your hormones. You can get an idea of other causes here: https://www.restartmed.com/low-sex-drive-women/
Hello, I had a Utertine Ablation in 2010 because of heavy periods. No more periods since 2010 yay. However, I started feeling really run down and depressed and I was never depressed before, always happier than most. I was beyond tired after sleeping a lot, weak, no libido, over weight about 15lbs. Tried the creams, gels, shots, no where near the results of the hormone pellets. Started hormone pellets in 2014 and it took a few tries to get the does right, 125 mg, of T, 50 mg of E, and also, a compounding pill of 205 mg of Progesterone, one per night by mouth because I still have my uterus. I always gain water weight at first. Then the weight comes off, even the 15 lbs I was carrying, I have more energy, feel stronger, better muscle tone, no more dry eyes and skin, skin looks better, I get wet again without Astroglide/Ky/etc., libido is excellent, in fact so much better than my husband who is 10 years younger than I. I have tried to get him to get his blood work checked but you know how some men are, he thinks he has no problems with libido. (Hardheaded). The hormone pellets have changed my life for the better. I feel incredible with them, like a new younger life. I get them every 3 to 4 months, going on 9 years. I get blood work done about EVERY OTHER time, 6 weeks after inserts. I only have great things to say about the pellets, I just wished my husband had them.
Hi Debrina,
Glad they are working well for you! It’s all about finding what works and sticking to it.
I had a hysterectomy at 44 and was on estradiol until about four years ago, when I went to a hormone specialist, who gave me pellets. I am going to be 70 and I still get them, and I accidentally slipped in front of my medical doctor had an absolute fit. I have never felt better, and I don’t understand why they would rather just give you a pill will make you suffer, then feel good. I have never had any bad problems with my pellets, and at this point, other than the fact that insurance doesn’t cover it, and it cost me a fortune I am not about to stop, but I would love to hear your opinion. Thanks.
Hi Angela,
There’s no good reason for doctors to be so against HRT except for negligence and an overall lack of understanding. I wish that wasn’t the case but I’ve lived in that world and I can tell you firsthand that the information that well-trained doctors don’t know about hormone replacement therapy could fill volumes. Even if they were as risky as they say, the entire ethos of medicine is to avoid a paternal medical system in which the doctor pushes his/her beliefs on you. You should be able to make medical decisions based on your risk tolerance and based on the correct information that your doctor provides.
I have to say I have been on bio-identical hormones for close to 4 years and I really hope I never have to stop. My skin is incredible, it is soft and smooth again as it was in my youth. I did not get any changes to my thinning hair but that aside I love that my vagina plumped up and became incredibly moist again. My orgasmic experience improved tremendously, and my mood is incredibly joyful 90% of the time. My libido is generally superb, but I am still a woman, and I am literally turned on more when a man can stimulate my brain. I had been single for 3 years prior to the pellet insertion and within a month I was on the hunt for a relationship do to my newly heightened libido. I have now been involved with a man 5 years younger than me and he is even on pellet therapy after I introduced him to it. I have gotten 4 of my friends to try it and so far, they all love it. I have met one woman who told me it did nothing for her other than improve her lubrication. She also is in an unhappy marriage and complains of painful sex unrelated to lubrication. I am not an expert but since I work with her daily, she appears to be extremely anxious, and I suspect adrenal fatigue, but I am no expert. I also know she tried twice and gave up. I doesn’t solve everything, but I generally think it helps mitigate some of the symptoms from lack of estrogen especially the sleep portion when it is supplemented with progesterone for those who still have a uterus. I am leaving this comment because I think people who have problems with it tend to post their dissatisfaction as opposed to those who are completely thrilled to have it as an option. In short, I feel the pellet therapy has given me back my vitality. I really hope more people will benefit from them. Good luck everyone!
Hi Gladys,
I’m glad to hear it’s working so well for you! Your experience is quite common but I would just point out that you don’t have to use pellets to gain all of the benefits you’ve mentioned here which is basically the point of this article. Bio-identical HRT of any time has the potential to provide the benefits you mentioned here, as long as it is dosed correctly. The crux of my argument is that you can obtain these benefits with minimal risks using other forms of HRT but at the end of the day, you should do whatever works best for you and it sounds like you’ve found it.
Hi I have been using pellets for about 9 years and I have bad facial hair so my question is if I stop the pellets will the facial hair stop?
Thanks
Carrie
Hi Carrie,
Possibly, it depends on what caused the issue in the first place. I would recommend reading this resource which discusses the underlying cause of hirsutism and some supplements that can help get rid of facial hair in women: https://www.restartmed.com/supplements-facial-hair-in-women/
I had a hysterectomy at age 30, due to cancer. I then had several years with no estrogen, and I was a crazy mess. I would honestly have killed myself had I not have finally found a woman gyn, who tested my levels and prescribed (ugh) Premarin. I had immediate benefit, but there were still problems. Thereafter, I tried everything then available, but it was still like I was in recovery from the sudden surgical menopause. Those were terrible years for me, especially trying to discuss that awful, improperly designed “Womens Health Initiative” with other gyns who seemed to have no research background at all, and were maddeningly uncritical of WHI conclusions, the stated basis for FDA denying women over 65 any HRT at all. Everything that was available: creams, vaginal inserts, pills, in addition to all sorts of behavioral and physical therapy was tried. UNTIL (yaaaay), I bit the bullet and tried inserts. I have been using the pellets now for 15 years. It took quite a few inserts to get it right, and still, I sometimes have a change in dosing. While nothing is perfect, I will say that I am now 82 and am healthy, happy, and living just fine. Everything is better: appetite, sleep, mood, skin, etc. I intend to stay with these inserts until my dying day, even if I have to fight the nursing home to do so. (haha…gallows laughter here.) One caution I give to others: Recently, an organization called BioTE had a huge marketing campaign in my area, recruiting (too) many doctors who were looking to make a little on the side: ER docs, some obstetricians, and others much less qualified to make hormone decisions to use their product. Treatment seems to be based totally on their numbers, not on the individual’s need. The actual pellet used seems to make a huge difference, as every person I know who used BioTE had either infections, extruded pellets, or unacceptable results. Perhaps they have changed their protocols, so one might check it for themselves. So. . .I am one who has benefitted remarkably from pellets, and I’m sad to see that there are companies who offer these treatments primarily as a money-making proposition for medical providers who don’t yet have enough money to satisfy their wants. What I have to say to others is: balance your hormones however you find works best for you. Bloodwork is essential, and also that you do your homework and don’t just rely on a random doctor: make sure your provider cares about YOU.
I started pellets a little over a month ago. My hair has fallen out by the hands full like I had chemotherapy. My scalp continues to be it by like it is going to continue to fall out. I have weight gain, bloating, breast tenderness, swollen painful glands, depression, anxiety, headaches, migraines, and a very concerned husband that told me my personality has changed.
At least with hormone cream I could stop it. I have no control. The levels with pellets start decreasing and will until potentially symptoms
return. So, my goal in having a constant level in my body is not going to work. They told me the cream fluctuates everyday. At least I felt good and was asymptomatic. Sheryl Drobny, RN
The fourth native estrogen, E4 Estetrol does not cause increases in SHBG. You need to include this in your information to make it more accurate.
I have been doing the pellets for 5 years with no problems until recently. When I started having vaginal bleeding, I went for an exam with a ob/gyn. She did a vaginal ultrasound and found the lining of my uterus is more than twice as thick as it should be for a 57 yr old. I had a biopsy which showed it was non cancerous. She advised me to stop the hormone therapy and said they were dangerous because the pellets aren’t regulated enough. Is this a normal side effect of doing the pellets? Will the lining of my uterus go back to normal over time? The clinic I went to never did any kind of physical exams during my treatment and the implants were done by a nurse not a doctor. I like the idea of the implants but not sure if this is a good fit for my body. Thanks for your advice!
Hi Sharon,
Hypertrophy of the endometrial lining is normal if you are taking too much estrogen, but it’s not normal if you are being adequately dosed. Yours is a perfect example of why I’m not a fan of the pellets because you don’t have the same level of control over dosing as you do over other methods. In most cases, the lining will return normal once the estrogen is removed or reduced.
I had a hormone pellet inserted three months ago and it hurt like crazy for ten days. It cost $480 per pellet, which insurance didn’t cover. I’m 68 years old, very active and tried the pellet because my endo said it would help my brain fog, give me more energy, and help me get fewer UTI’s.
I had severe side effects: breast tenderness, hair loss, scalp, chest and thigh acne, lowered voice, and way too much libido. I was getting into fights with everyone (mostly with my husband). I also gained eight pounds during the first two months, which I have not lost going into month four.
I felt horrible for two months and am now just starting to feel better now, after three months. I will not continue the pellets and will soon go back on topical Estriol/Ellage cream every night as it prevents my recurring UTI’s and gives me no side effects.
Hello I’ve been on pellets for 6 months I tried the creams and gels bio identical they didn’t work I had total hysterectomy in 2000 been going three hell ever since finally found a doctor to test my levels which were 0 then start me on the pellets he placed 3 I felt a difference within 2 weeks I have appointment this month for my 3rd insert they do not cost tons like I read I pay $260 each time that covers the whole procedure my insurance covers the bloodwork this procedure is done at UK in Lexington KY I am so grateful to have found my doctor I have lost 14 pounds I knew my weight was hormonal because I am not a big eater just wanted to say I feel they are the safest thing I’ve ever done for hormone replacement in 23 years and they work
I LOVE my Biote pellets! Before my doctor started me on the pellets she ordered blood work to make sure I received the correct dose. I go to a functional medicine doctor (thank GOD) not a conventional medical doctor as they can’t seem to find their A&% with both hands. I have lost weight, my libido is awesome, no vaginal dryness and I’m extremely happy! I also use your T2 and Berberine which have helped even more with my weight loss. I am hypothyroid and have always been overweight. I’m now at 118 lbs at 5’4″. I haven’t weighed 118 lbs in 38 years!!!! I also do intermittent fasting. I’m never hungry, I have no sugar cravings, I only eat whole foods, no junk food or processed food and I don’t want them!
I have learned alot from your articles concerning my thyroid, which led me to my functional medicine doctor! Thank you!!!
Hi Caroline,
Glad to hear you’re doing so well and you’ve found what works for your body! Thanks for sharing.
Hello Dr. Childs,
I’ve had 3 pellet hormone therapy procedures. Infection occurred in each of the 3 procedures and the infections lasted for weeks requiring antibiotics. One of the pellet hormone therapy procedures resulted in all the pellets being rejected by my body that resulted in my body pushing the pellets out through the injection site. Each procedure was expensive!
Hi Henry,
Unfortunately, infection at the insertion site is a potential risk when using hormone pellets and is one of the reasons I don’t recommend this route.
Interesting reading all these comments. I have had my 2nd pellet insertion about three weeks ago. Important to note that I am almost 59 and was in full menopause at age 38. No surgeries, no chemo, just when I stopped my periods and the hot flashes began with a vengeance. After 20+ years I decided it was time to see what might help with the hot flashes (violent), weight gain, pain intercourse, dryness, and depressed libido. Pellets seemed to be my best option. My doctor also recommended oral progesterone.
After first insertion: noticed almost immediately an decrease in vaginal dryness (gone) and breasts were tender (like when I had periods). Libido increased slightly. A couple of pounds gained and tired. However, my biggest complaint was the pain in my hips, thighs and knee joints. Started rather dull, noticed a huge decrease in my range of motion in my hips and sometimes, the pain is almost unbearable and wakes me up. I’ve been a fitness instructor for over 30 years and have never had hip or knee issues, ever. I find it hard to believe that both sides of my body would experience this at the exact same time. After my 2nd pellet insertion, I have had constant break through bleeding (using tampons again, what??), hot flashes are back, a little more weight gain, insomnia and the pain in my hips and lower legs to the knees is everyday, constant and sometimes debilitating. The pain wakes me up and sometimes prohibits my movement. Nothing else has changed in my life so I must attribute it to the pellets or the oral progesterone I’m taking? I think I need to consider other options as the side effects are far outweighing the symptoms I had going into the pellet therapy. I’m just super frustrated. Feeling like I shouldn’t have messed with it at all.
Hi Stacey,
Breakthrough bleeding and breast pain are classic signs of excess estrogen. Your other symptoms are consistent with an imbalance in estrogen:progesterone as well so it appears that you probably were given an improper dose of hormones.