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5 Benefits of using T3 Medication + Who Should Use It

Many patients on levothyroxine or synthroid stand to benefit by simply adding a small amount of T3 medication to their regimen. 

T3 is metabolized in the body in a different way than T4 which makes it special.

It's also the strongest and most powerful of all the thyroid medication BUT it must be used correctly.

Learn about the benefits of T3 including which patients should use T3 and why in this post: ​

More...

What is T3 Thyroid Medication?

​T3 thyroid medication is the strongest of all thyroid medication. 

Why?

Because T3 is the active thyroid. 

But most patients with hypothyroidism are not taking T3 thyroid medication.

​How come?

Despite the medication being quite safe if used correctly, many physicians simply aren't comfortable with prescribing it.

​As a result most patients are taking some form of T4 thyroid hormone. 

You know these medications well: Levothyroxine, Synthroid and Tirosint

​All of these medications fall into the class of T4 thyroid medications. 

And, unfortunately, they are considered to be weaker when compared to pure T3.

T4 thyroid hormone must be activated in your body through special enzymes.

Thyroid conversion with leptin resistance

When it is activated your body changes its structure and turns T4 into T3.

Once it's in the T3 form it can then get into your cells and activate genetic transcription through its action on nuclear receptors.

But your body can also INACTIVATE T4 by turning it into reverse T3. ​

​And this is one of the reasons that using T3 thyroid hormone is so special. 

Instead of providing you with a medication that your body must activate, you can instead bypass this activation process and provide the body with the direct and active thyroid hormone (T3). ​

Is using T3 actually dangerous as most physicians would have you think?

It turns out that, as long as it is used correctly, there are very few side effects of using T3.

More and more physicians are starting to add T3 to existing doses of T4.

This might come in a combination such as Levothyroxine + Cytomel (usually in small doses).

But T3 can be used much more effectively, and safely, at even higher doses.

In fact most patients stand to benefit tremendously by adding in a small amount of T3 to their existing dose of T4 - even if it means lowering their current dose of T4.

​T3 can also be safely combined with natural desiccated thyroid hormone (you can read case studies here). 

​But the question remains:

Who should consider using T3? ​

  • Bottom line: T3 is the strongest form of thyroid hormone and can be prescribed by your doctor. Certain patients stand to benefit by adding doses of T3 to their existing T4 dose. Unlike T4 thyroid hormone, T3 does not require activation to exert its effects in the body. 

When to use T3 thyroid medication

​Determining if you would benefit from T3 thyroid hormone is not as difficult as you might think. 

As a general rule of thumb:

The more medical conditions you have, the more excess body fat you have, the more medications you are on, the more inflammation in your body... the more likely you are to benefit from T3.

Why?

Because all of these conditions create an environment ​inside of your body that favors the production of reverse T3 over T3. 

That means you are in a state of thyroid resistance.

Patients who benefit from cytomel

​In a nut shell your body is basically blocking the action of thyroid hormone at the cellular level, this can occur even though you have "enough" thyroid hormone floating around in your blood stream. 

When it comes to thyroid hormone we really don't care how much is floating around in your blood, we really only care if thyroid hormone is getting inside your cells and turning on your genes.

But we don't have a great way to test for this, so instead we use surrogate markers such as reverse T3 and sex hormone binding globulin.

Most patients who ​stand to benefit from using T3 thyroid hormone fall into one or more of the following categories: 

While this list isn't exhaustive, it does include the majority of patients who might benefit from the addition of T3. 

It's also important to consider T3 therapy (either in addition to your current dose of T4 or NDT) if you are having any issues or remaining symptomatic despite taking thyroid medication. 

​This might manifest as an intolerance or sensitivity to thyroid medication, or an inability to absorb your thyroid medication. 

Benefits of Using T3 Thyroid Medication:

Because of the unique way that T3 is utilized in the body when compared to T4 it comes with several benefits that we should talk about. 

These benefits have to do with the fact that this medication does NOT require an activation step in the body, which means that it is active once it is absorbed. ​

#1. More Weight Loss

Another VERY important aspect of T3 is its ability to influence weight loss.

​So does T3 help with weight loss?

The answer is absolutely!​

In fact this effect is much more pronounced than T4 and/or NDT.

Why does T3 help with weight loss more than T4? 

​T3 has a greater action on the factors that influence your metabolism than T4 does. 

Studies have shown that patients taking suppressive doses of T4 thyroid hormone, resulting in a low or "suppressed" TSH still have a lower metabolism than what would be expected

Obviously a low metabolism would result in an inability to lose weight and this might explain why so many hypothyroid patients have issues with weight loss despite taking thyroid hormone. 

In addition other studies have shown that ​patients with "normal" TSH levels tend to have lower levels of both free T3 and free T4 compared to age matched controls. 

​This reduction in jthyroid levels may help explain the difference in weight among hypothyroid patients and euthyroid patients. 

Basically your free T3 and free T4 levels seem to matter much more than your TSH when determining how you will feel taking thyroid medication. ​

And lastly, other studies have indeed confirmed that patients ​who take T3 thyroid hormone over T4 show that they have more weight loss and a higher metabolism WITHOUT negative side effects. 

This doesn't necessarily mean that everyone will benefit in this way from T3 but it does mean that using T3 should be a serious option for patients who are not tolerating T4 only thyroid medication (or NDT).

thyroid metabolism reset poster for side bar

#2. Higher Basal Metabolic Rate

​Another benefit of T3 medication is that it increases (or normalizes) your basal metabolic rate. 

Hypothyroid patients are very susceptible to having a lower than normal metabolism for a variety of reasons.

First:

Having low thyroid itself changes your metabolism and will lower it. This is one of the main reasons that weight gain is a symptom of hypothyroidism. ​

Second: ​

The second reason is also very common and more sinister than the first.

Because hypothyroid patients tend to gain weight these same patients usually undergo calorie restricted weight loss programs to try and lose weight. 

Unfortunately calorie restriction actually makes the problem even worse by further lowering the metabolism.

The combination of low thyroid hormone plus metabolic damage from calorie restriction results in a metabolism that is usually in the range of 1,200 to 1,500 calories burned per day.

This is why many hypothyroid patients have difficulty with weight loss and why Doctors look at you like you're crazy when you tell them that you're eating 1,000 calories per day and still not losing weight.

The benefit ​of using T3 is that it can help heal your metabolism and increase your basal metabolic rate through its influence on your mitochondria. 

#3. ​Reduction in Hypothyroid Symptoms

​Another benefit of using T3 is that many of your true hypothyroid symptoms will likely improve or be reduced dramatically. 

I'm talking about hair loss, fatigue, weight gain, brain fog, etc.

These symptoms are all indicative of low tissue levels of thyroid hormone and many of these symptoms persist even while taking thyroid medication like T4.

But once you start taking T3 thyroid hormone your body is able to take up the T3 and use it at the cellular level.

This results in greater tissue levels of thyroid hormone in your skeletal muscle (increasing metabolism and energy), your hair follicles (reducing hair loss), ​and your brain tissue (reducing depression and brain fog).

While it is true that other factors like nutrient deficiencies may contribute to your symptoms, it's easier to distinguish the cause of these issues when you start taking T3. ​

#4. ​Higher Body Temperature

​Through its influence on energy production in your mitochondria T3 can actually help to increase or normalize your body temperature. 

Your total body temperature is a reflection of the amount of energy you are producing and the amount of energy you are burning. 

Many patients walk around with very low body temperatures (in the 95-96 degree range) as a consequence of hypothyroidism. 

This low body temperature is almost always associated with a slower metabolism and a low basal metabolic rate.

T3 thyroid hormone helps improve your body temperature in several ways:

First:

It directly mediates energy production in your mitochondria (this helps boost your metabolism). ​

Second: 

​T3 helps the body burn fat tissue and activate brown fat to further increase metabolism and increase fat burn

​The addition of T3 helps normalize these processes and can increase your body temperature to normal levels (and help increase your metabolism in the process). 

#5. ​Improvement in Other Hormone Imbalances

​One of the main reasons that thyroid patients DON'T get better when starting thyroid hormone is due to its effects on other hormones in your body. 

Hypothyroidism helps potentiate two very important hormone imbalances:

Insulin resistance and leptin resistance.

​Unfortunately, using T4 thyroid hormone can help reduce the symptoms of hypothyroidism but it won't necessarily treat these hormone imbalances if they are present. 

That is where T3 comes in handy.

T3 has been shown to help reduce insulin resistance (which will help with weight loss and help normalize blood sugar).

Leptin resistance and hypothyroidism

​T3 has also been shown to help reduce leptin resistance

This is very important because there are currently very few treatments that can help lower leptin levels.

If you aren't aware, leptin resistance creates an environment in your body which makes weight loss almost impossible unless it is reversed. ​

NDT vs pure T3​

What about natural desiccated thyroid hormone?

NDT is another form of thyroid hormone replacement and NDT does contain some amount of T3 in it.

1 grain of NDT contains about 38 mcg of T4 thyroid hormone and 9mcg of T3 thyroid hormone.

It also contains some other less biologically active thyroid hormones like T2.

​NDT is another great thyroid hormone replacement medication but just like T4 medication it does fall short in certain circumstances. 

​Because NDT is mostly T4 (about 80%) it is still subject to reverse T3 conversion and might cause issues in some patients. 

In addition, certain patients may need temporary supraphysiologic doses of T3 for short periods of time to wash out the reverse T3 and reset the system.

Using higher doses of T3 during this time period or using the combination of T3 and NDT together can help overcome this issue.

It's best to consider NDT as another potentially helpful medication, but it shouldn't be considered the "best" thyroid medication. 

SR T3 vs IR T3

T3 medication comes in two varieties: 

  • Immediate release T3 <--- Including medications like Cytomel and Liothyronine
  • Sustained released T3 <--- This is a compounded medication of liothyronine (usually bound to methylcellulose)

It's important to realize that these medications are the same in that they both contain T3 thyroid medication. 

How they differ is in how quickly they are absorbed into your body.

Immediate release T3 is absorbed rapidly into the body and peaks in the serum within 2-3 hours usually. 

In patients who are sensitive to T3 they may develop heart palpitations or a jittery sensation around this time. ​

These side effects occur as a result of this rapid absorption and the sensitivity of cardiac myocytes to T3. 

In your heart T3 has a direct action on the calcium channels which causes the heart to pump harder and faster (which may lead to heart palpitations).

This is compared to other systems in the body where T3 has to directly interact with the nucleus and results in changes to genetic transcription (this process often takes weeks).

​If you fall into this "sensitive" category and you are experiencing these side effects of IR T3 (heart palpitations, etc.) then in most cases simply switching from cytomel to SR T3 is enough to fix the problem. 

In SR T3 formulations of T3 medication, the T3 is bound to a glue like substance (usually methylecellulose) which delays the absorption. 

This allows your body to slowly absorb T3 throughout the day and will limit the "flood" of T3 that is seen 2-3 hours after taking IR T3. ​

Whenever possible my general preference is to use IR T3 over SR T3, but that isn't always possible.

Another limiting factor that should be considered is that Cytmoel and generic Liothyronine both contain inactive fillers. ​

In some cases patients may react to these inactive ingredients necessitating a switch from IR T3 to SR T3.

​In most cases (probably approaching 70% of patients), however, patients tolerate IR formulations of T3 such as Cytomel and Liothyronine quite well. 

Side effects of T3 to watch out for

The side effects of T3 come from taking too much of the medication or from the inactive ingredients. 

As long as you dose the medication correctly and use the proper type of T3 medication (IR vs SR T3) there are generally very few issues.

Occasionally patients may present with the following symptoms when taking T3: ​

  • Heart palpitations
  • Jittery sensation
  • Increased anxiety
  • Hot flashes or feelings of being warm or too hot
  • Temporary increase in hair loss
  • Headaches

These would be considered less serious side effects of taking T3. 

If you experience any further side effects not listed here it's best to consult with your prescribing physician. 

I do want to focus on a couple of these side effects for a moment...

​First is the hair loss. 

T3 can absolutely cause a significant but temporary increase in hair loss.

This is worth mentioning because hair IS a symptom of hypothyroidism and this side effect may be confused with worsening symptoms when in reality the opposite is true.

Remember that this hair loss is temporary and usually subsides within 2-3 months.

The next is headaches.

Unfortunately some patients experience headaches when starting T3.

If this happens to you the best option is to consider switching to SR T3.

Back to you

T3 thyroid medication is quite powerful and safe if used correctly.

Using T3 comes with special benefits due to how the body metabolizes and uses thyroid hormone.

In some cases patients may require T3 in addition to their current thyroid medication (like T4 or NDT). 

Most patients who stand to benefit from T3 are patients who have not felt better on other thyroid medications or patients with extreme weight loss resistance.

Use the outline above to determine if T3 might be helpful for you.

Now I want to hear from you:

​Is T3 helping you with weight loss?

Is it helping you increase your body temperature or reduce the symptoms of hypothyroidism?

Why or why not?

Leave your comments below! ​

Dr. Westin Childs
 

I'm Dr. Childs and I write these posts. I'm a physician that specializes helping patients lose weight, have more energy and FEEL better. My practice focuses on hormone imbalances, thyroid issues and weight loss resistance. My goal is to provide the BEST information out there on the internet that is both actionable and trustworthy. Get my free ebook: Hashimoto's Diet Guide here. You can also find more about my personal journey back to health here.

Click Here to Leave a Comment Below 41 comments
laurie a goetzinger - April 7, 2017

I’m currently taking 25mcg of Cytomel along with 50mcg of Unithroid. I had my thyroid taken out last March due to cancer. I started on 100mcg or Synthroid. I then switched to Unithroid due to cost. Since then I’ve had muscle or joint or whatever pain all over my body. My Dr. is working with me to try Cytomel. I think it’s working, not sure. My Pain is hard to deal with. Whats going on? Am I still very hypo? or is the pain from taking too much medicine? The weird thing is, I felt great right after my surgery and when I wasn’t on anyting. Why?

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Holly - April 8, 2017

What about the anxiety or nervousness? I have been struggling with this since starting just 5mcg of cytomel about three months ago. I have cut into half and take with meals and it seems to do better, but sometimes I have that “internal trembling” when I try to up the dose back to 5mcg. I have rechecked my labs and things are looking much better, my FT3 is finally up to 3.0 (from 2.2) and rT3 is down from 20 to 15. I am now having some return of fatigue (initially had sooo much better energy, I could get out of bed!) though and believe I may need to up the dose but don’t want the anxiety. My MD doesn’t compound it but would you think a SR type might be better? I might have to seek out another provider to follow me but it may be worth it. Your thoughts? Thanks again for all of your valuable information.

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April L - April 8, 2017

My doctor has agreed To raise my cytomel to 50mcg it has not helped my weight loss and I still think it is too low of a dose. I have had no side effects either.

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    Dr. Westin Childs - April 12, 2017

    Hi April,

    Rarely does changing your thyroid dosing (even adding T3) lead to weight loss by itself. If you read my case studies you will have a better idea of what I’m talking about.

    Reply
Heather - April 18, 2017

Is Topomax one of the drugs that can increase the conversion of T4 to RT3

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Cheri - April 24, 2017

Cytomel is shown to increase blood glucose. If I’m trying to control my BG (high end of normal), then wouldn’t the cytomel be doing more harm than good? Am currently on 5mcg of cytomel and Levo. I’m thinking of discontinuing the cytomel because of borderline high BG, now I’m not so sure. Diet and exercise are optimal, including HIIT and paleo.

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    Dr. Westin Childs - April 24, 2017

    Hi Cheri,

    I think you are confused as to how T3 works in your body with glucose and insulin levels. I suggest reading more on the topic, you can also find relevant information on my blog.

    Reply
      Cheri - April 25, 2017

      Thanks for your response, but I find it both uninformative and dismissive. I have spent many hours perusing your blog and find no relevant information regarding the fact that cytomel is shown to raise blood glucose. An important fact if one is trying to lose weight. It’s your blog, so you can certainly respond any way you see fit, but I would have appreciated a link or some actual information addressing the issue of cytomel and blood sugar. That you choose not to provide that and rather berate my lack of knowledge makes me wonder if perhaps the makers of cytomel are offering you some consideration. Thank you.

      Reply
        Dr. Westin Childs - April 25, 2017

        Hi Cheri,

        My comment wasn’t mean to be dismissive, it was meant to guide you into re-evaluating your current understanding of cytomel as it relates to insulin and glucose.

        Just due to sheer volume to questions and emails I get on a daily basis it is impossible for me to adequately respond to every question/request. This leaves me with the option to try and answer some questions and not others, or to simply ignore them all – I choose the former.

        I also do not get kickbacks from the makers of cytomel, I write about what I find interesting and what I think will be helpful.

        Reply
Terry - April 24, 2017

I would love to see what the test numbers should be for people who are already medicated, especially with NDT. I think I need more T3, but don’t know how to interpret my recent test results except to say everything is borderline near the bottom of the ranges except for the TSH, which is officially low, and the reverse T3 = 15. I’d like to be at least mid-range on my free T4 and free T3. Is that a reasonable goal?

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Jeri - April 24, 2017

I started taking 5mcg of cytomel once a day about a month ago, and then increased to twice a day about a week ago. I have not seen/felt any positive effects of the medication yet. About how long does it take to start noticing a difference? I’m on 75 mcg of levothyroxine and cannot shed 5-10 lbs or get rid of other pesky hypo symptoms (extreme fatigue, hair loss, joint pain, etc). Thank you! I have gained a wealth of knowledge from your podcasts!

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    Dr. Westin Childs - April 24, 2017

    Hi Jeri,

    T3 dosing guide, titration guide and lab testing will be in my membership program, but I don’t have it available yet.

    Reply
    karen - April 25, 2017

    Jeri,
    I had the the exact same experience and result, w/Citomel about 3 years ago. I didn’t feel any better, and noticed more symptoms like, hair loss, fybro, lethargy, and weight gain!! I went off, tried Tirosint, and the script went up to $168. for my part of the prescription, I said forget it….back to Synthroid. Nothing has changed there either…but the doc sais, least it’s not worse…..wow, what a consolation 🙁

    Reply
Ashley - April 24, 2017

Hello,

Firstly, I wanted to thank you for the wealth of information you’ve given! I bought your program, and an going to start it this week. I am currently on Levoxyl and Cytomel once a day, but my doctor wants n to start doubling my cytomel and take it twice a day. My question is can Levoxyl and Cytomel be taken at the same time for the morning dose? And what time is day is best for the second side of Cytomel? I asked my doctor but he did really seem to think it mattered. Also, I purchased b12 injections from you and I was wondering what the shelf life is on those?

Thank you so much!

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    Dr. Westin Childs - April 26, 2017

    Hi Ashley,

    In terms of taking your T3 and T4 there is no “best” time to take them, what matters is finding a schedule that fits your personal schedule and that doesn’t result in heart palpitations, etc.

    The B12 will last up to 120 days if refrigerated.

    Reply
Eleanor Smith - April 24, 2017

I’ve been on Levythyroxine for about 10 years. I finally talked my endocrinologist into giving me T3 (Cytomel). My starting blood tests showed Free T4 at 1.2 ng/dL, T3 at 76 ng/dL and a TSH of 1.14 uIu/mL. After six weeks my T3 levels went up from 76 ng/dL to 101 ng/dL. After another six weeks my T3 levels are back down to 77 ng/dL. My TSH is down to 0.78uIu/mL and my T4 is down to 1.1ng/dL. The weight is not coming off despite my best efforts. Why would the T3 number go up again when I’m following the prescribed instructions. I’m taking half of a 5MCG tablet in the morning and the other half at 2PM. When I asked my doctor about it she said “The cytomel is not reflective on the T3. The change in TSH reflects the addition of cytomel and it is mostly for you symptomatically.” I’m frustrated and confused as it’s the opposite of what I’ve been reading.

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Sandy - April 24, 2017

Cytomel caused severe insomnia for me.

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Alison - April 24, 2017

Life changing!!!

Sustained Release T3 has been amazing for me after 8+ Years on Thyroxine T4 only treatment.

The only reason I found out about T3 was doing my own research & finding help from people like yourself willing to share your knowledge.

So THANK YOU!
Founder of Hashimoto’s Heroes from Australia

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BetteJo - April 25, 2017

I have had Hashimotos for almost twenty years…what a rollercoaster ride! I was taking Synthroid for a long time and I was very sick. I had a nodule that was core biopsied and ultrasonically guided. A blood vessel was nicked and I developed a blood clot in my thyroid-it was difficult to swallow. I had a hysterectomy shortly after and was anemic roo. They were afraid that I had a blood cancer because my red blood cells were immature. I was napping daily and could hardly wake up at times. I was 34 years old and falling a part. Even long after my biopsy, I had a tightness in my neck and felt choked, mostly in the middle of the night. My doctor chalked it up to nerves until I went to the ER and was diagnosed with hypothyroidism. Years later not feeling well, I decided to talk my dr into letting me try Armour…Yikes! I had heart palpations and I tried to work through them for a year. My dr said I was probably sensitive to the other hormones in it. I am now taking Levo and a generic form of Cytomel. I am gluten free and so are the meds. It has made a big difference. My fingers and feet don’t feel as swollen as they used to be. No more heart palpations. My Tsh goes up and down at times, but this is so much better. I also have cleaned up my diet and try to eat real foods as much as possible. It has not been an easy journey but I have seen light at the end of the tunnel. One day at a time is my motto.

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Pamela - April 25, 2017

My medication made me gain weight. I started out with a functional doctor who had me on NDT. I put weight on. I then went to an Endocrinologist who took me off the NDT, put me on Levo and continued to gain weight but not as quickly. He then added t3 and I continued to lose hair and gain weight. I got fed up and went off of everything. My energy levels seem ok but I can not shed this weight which really frustrates me since I eat so healthy! Any suggestions?

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Allison - April 25, 2017

Hi- I started synthroid (on 50 mcg) about a year ago, but couldn’t lose weight, hair loss etc.., just added low dose of cytomel (5mcg) last week in hopes that hair loss will stop, help with weight loss. Any idea how long it will be until I know if this new combination of t4/t3 is right for me?

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Lynn Thompson - April 25, 2017

Hello
I had to have my Thyroid removed and I also had a quite large goiter removed. Has this all done on 3/1/2017. I am on Synthroid 125mg and I feel like crap.Exhausted ALL the time, hair loss.I am jittery all the time and very cranky.Headaches every morning. Now, I am losing weight because I had gastric bypass surgery in Dec 2016.I have lost 85 lbs so far,With the gastric Bypass Surgery am I making enough enzymes to activate the Snythroid? Should I be taking the T3? I am so confused by all this thyroid info.

Lynn

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Irina - April 25, 2017

Dr. Child’s, I was on 20 mcg if T3 for a month. My rT3 went down from 16 to 2. My vertigo and hair loss totally disappeared! My TSH went up to 35(!) from 0.045. My antibodies went down from 38 to 26. T3 and T4 dropped down dramatically.
I am dealing with Hashimoto for 30 years and never my TSH was 35. Can you explain to me what’s going on?
Irina

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Marcia - April 25, 2017

I’m taking 120mg armour and recently had lab results of total T3 297 and 5.3 free T3, sex hormone binding globulin of 50, and TSH with reflex to FT4 is 1.62 so dr said to leave things the same. A couple of years ago she was letting me try cytomel and I was feeling so great, better than I had in all the years of taking thryoid supplements, and was losing weight so easily. But she stopped prescribing it because the T3 was too high and she felt it was dangerous. SO have not felt good for a long while again. Lots of fatigue and pain in my body but then I also have fibromyalgia and chronic fatigue and diabetes. I want to try cytomel again but since she is not comfortable with prescribing it I thought if I knew what dose of the armour or even levothyroxine would be correct with which dose of cytomel, she is usually pretty open to working with me and might let me try it if I had the information to give her. Another doctor had mentioned that it sounds like the T3 is just not getting converted or into the cells or something, yet it shows too high in lab tests. Please help me, I don’t feel I have ever gotten this problem addressed and hope that you can offer some information from the lab results I have given. Thank you. I will also try to share the article with my doctor, as well as read it again myself.

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Valerie - April 25, 2017

I have been taking T 3 liothyronine 7.5 mcg 12 hours apart for the last year. I cycle up dose daily until temp reaches 97.6 and then wean down slowly. I feel better overall but still cannot lose weight very well. I was at my highest weight in Jan and started your fasting protocol and lost a few pounds. I am have now plateaued. I am not sure what hat else to do. During a fasting day recently my body temp went to o 33 c.

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    Dr. Westin Childs - April 25, 2017

    Hi Valerie,

    You will have to break through the plateau, once you do that you should be able to continue with the fasting again for more weight loss. Most people reach 2-4 plateau’s during their weight loss journey.

    Reply
Altaf - April 25, 2017

Hello Dr. Child’s,

Help! I am currently taking 320mcg of T3 liothyronine ( from Germany) a day (160 x 2) along with 600mg of Lopressor after having been diagnosed with Hashimotos and thyroid hormone resistance after 4 years of being on t4 thyroxine and 3 miscarriages. I gained over 60 pounds since being diagnosed. I am insulin resistant, not sure of leptin resistance. While I have had some relief from my hypothyroid symptoms, I have in fact gained weight rather than lost while being on T3. I still have a huge amount of water retention. Each time we raised the dose I would feel better for a few days and depuff, but then everything would return to hypothyroid.
I have tried to call your office to see if I can schedule a Skype consult with you, as I live in Kuwait and am desperate for help with my weight ( 260pounds now from 180) . Please, is there a way I can schedule a consult over the phone or Skype with you ASAP. I am truly desperate and have lost so much from being misdiagnosed over and over, and can’t understand why T3 hasn’t worked completely for me. Thanks very much.

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Abelone Philippa Mørk - April 25, 2017

I am hyperthyroid and feel bad, my muscles are weak, I have brain fog and it is a struggle to live my life. What happens if I take cytamel for example?
Sorry, I am Danish so my english can be wrong.

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JJ - April 25, 2017

I am on 100 mg of T3 a day and people are saying it is why I have insulin resistance , is this true? all T4 goes to ReverseT3 because of the insulin and leptin resistance

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Christine - April 25, 2017

where can you purchase SR T3 please as I would like to try instead of the liothyronine which causes heart flutters and stomach pain. can I get this anywhere online as I know my GP wont be happy to change anything. They only keep the liothyronine as its been prescribed for a number of years. thanks

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Altaf Al-Hakim - April 25, 2017

Hello Dr. Child’s,

Help! I am currently taking 320mcg of T3 liothyronine ( from Germany) a day (160 x 2) along with 600mg of Lopressor after having been diagnosed with Hashimotos and thyroid hormone resistance after 4 years of being on t4 thyroxine and 3 miscarriages. I gained over 60 pounds since being diagnosed. I am insulin resistant, not sure of leptin resistance. While I have had some relief from my hypothyroid symptoms, I have in fact gained weight rather than lost while being on T3. I still have a huge amount of water retention. Each time we raised the dose I would feel better for a few days and depuff, but then everything would return to hypothyroid.
I have tried to call your office to see if I can schedule a Skype consult with you, as I live in Kuwait and am desperate for help with my weight ( 260pounds now from 180) . Please, is there a way I can schedule a consult over the phone or Skype with you ASAP. I am truly desperate and have lost so much from being misdiagnosed over and over, and can’t understand why T3 hasn’t worked completely for me. Thanks very much.

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Helen - April 25, 2017

Hello dr. Childs;
Thank you for writing this information I’m sure it will help lots of people.
I am super frustrated I have been taking 150 mg NDt for almost two years and my dr.added 60 mg of T3 in addition but my temperature is still 36.2 which is up from 35.8 but I’m still not losing weight even though I have a 90% Paleo lifestyle. I have no thyroid due to thyroid cancer and I have had a hysterectomy. I’m 57 years old and frustrated can you give me any advice?

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Marsha S - April 25, 2017

Hi Dr. Childs. Adding liothyronine 10 mcg for two months to my .88 mcg Levo actually resulted in hyperthyroid symptoms. So the ir t3 was reduced to 5 mcg. But it definitely took care of my conversion problem. Still working out some other issues, but wanted to stop by and thank you for the valuable info. It has benefited many.

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