A Patient Guide to the Endocrine System: Hormones, Glands & More

A Patient Guide to the Entire Endocrine System: Hormones, Glands & More

The endocrine system is probably one of the most important systems in your entire body. 


Because it produces the hormones that make You You

Small changes to these hormones can result in big symptoms in your quality of life. 

Fatigue, weight gain, mood changes and libido changes are just some of the consequences of hormone imbalance in this system. 

This guide will teach you everything you need to know (from the perspective of a patient) about your endocrine system and how to determine if you are suffering from hormone-related issues.


What is the Endocrine System?

The endocrine system produces hormones (1) which drive your sex drive, it regulates your weight through your thyroid, it helps you sleep through the secretion of melatonin, it helps to provide you with energy through adrenal gland function and much much more. 

These hormones work together in a complex way to help regulate each other and help you feel healthy. 

But what happens if you have issues with any one of these organ systems?

You may experience serious symptoms ranging from quality of life disturbances (fatigue, weight gain, depression) to life-threatening conditions

For the purpose of this article, we are primarily going to focus on those issues which affect your quality of life. 

So if you are experiencing issues such as fatigue, weight gain, depression, chronic pain, low sex drive, inability to build muscle mass, bloating, anxiety, menstrual problems, infertility and so on, then this is the post for you. 

All of these problems may be attributed to slight disturbances in hormone levels in your body. 

The more serious issues are rarely ever missed by Doctors, but these chronic quality of life issues may be more difficult to diagnose and manage and may be missed by your Doctor. 

Conventional Approach to Hormone Management

Doctors are great at many things, but hormone management is not one of those things. 

Doctors are trained to think about hormone balance in your body in a very black and white way. 

From their perspective, either there is some massive problem such as a huge overdose of hormone in your body, or there is so little hormone floating around that it is basically non-existent. 

In this way, they rule out the possibility that hormone balance lives on a gradient or on a spectrum

On a spectrum, disease or imbalance can exist to varying degrees until it gets worse and worse and reaches some critical point. 

You can think of this as your hormones functioning as a percentage of a whole. 

For instance:

In the optimal setting, your body produces 100% testosterone which helps to control your mood, lean muscle mass, libido and so on. 

As you age, or as other factors influence your body, this percentage may drop to 80% of normal and so on. 

As this percentage drops you may begin to experience systems which lead you to your Doctors office (symptoms such as these in the case of low testosterone). 

So what's the big problem?

These symptoms will largely be ignored unless your testosterone drops to less than 10% of whatever the reference range of the lab is. 

This leaves you feeling poorly for a long period of time as this percentage of hormone function drops over time. 

What's interesting is that Doctors are aware of this spectrum of disease as it exists in many other areas in medicine, but they fail to understand it in the context of hormone balance. 

Take for instance high blood pressure (2) or chronic kidney disease (3). 

Both of these conditions exist on a spectrum with varying degrees of severity. 

But these diseases are NOT ignored in their early stages, in fact, they are often treated aggressively

Why doctors don't apply this logic towards hormones is a story for another day, but for now just realize that it exists. 

The good news is that there are therapies and treatments that you can undergo to potentially help improve your endocrine system if you are feeling poorly. 

Key Organs in the Endocrine System

In this section, I'm going to walk you through some of the most important organs in your body (the ones that secrete and control your hormones). 

I will focus on the major functions of these organs and what you may experience if there is a problem with your body. 

As we've already discussed, the hormone systems in your body tend to be largely ignored by conventional physicians unless there is a massive problem but what they fail to recognize is that there can be a sub-optimal performance in many of these systems. 

Even though we are going to discuss these organs individually it's important not to lose sight of the fact that the body functions as a unit with all of the parts working and moving together. 

So when there is a problem in one system there is almost always some other down-stream consequence as a result of the initial issue (4).

This can cause a chain reaction which can often be treated by looking for the "root cause". 

Keep this in mind as we discuss each system! 

Also, this is not a complete guide to all of these organ systems.

We could write an entire book on each topic (indeed, books already exist on these topics!), but we can hit the highlights and those issues that most commonly affect people. 

Whenever relevant, I will also touch on some of the more controversial and integrative/alternative diagnoses associated with each gland...

#1. Adrenal Gland

Your adrenals sit on top of your kidneys in your abdomen and are probably best known for their ability to produce cortisol and adrenaline. 

Cortisol is often cited as the energy and stress hormone which is secreted in high amounts when your body is under stress. 

Cortisol helps your body tolerate stress by altering other hormones, helping you increase energy and focus and by increasing glucose breakdown for immediate use (5).

Adrenaline is another hormone which is secreted during times of "fight or flight" from a portion of your adrenal glands. 

Adrenaline helps increase blood pressure, regulate your metabolism and so on. 

Together you can think of your adrenal gland as a gland designed to help you tolerate and manage stress. 

Stress is something that we all deal with on a daily basis and we all know that a healthy level of stress is a good thing, but what happens when stress becomes too much?

Is it possible that you can exhaust your adrenal glands and cause problems with cortisol to the point that it is no longer functioning at an optimal level (6)?

This is the idea behind the diagnosis of "adrenal fatigue"

Those with adrenal fatigue often experience the following:

  • Constant and chronic daily fatigue
  • Sensation of feeling wired but tired
  • Reliance on caffeine for energy
  • Cravings for sugary and salty foods
  • Afternoon crash around 2-3pm
  • Inability to fall asleep despite feeling exhausted
  • Reduced quality of sleep

One of the main problems with adrenal fatigue is that people who experience the symptoms associated with this condition often have normal cortisol levels. 

So, while this remains a popular diagnosis among integrative circles, it's not an accepted diagnosis among conventional physicians. 

But should it be?

It certainly remains logical that constant and perpetual stress may lead to negative consequences in the body. 

mediators of stress in the body

We know from many studies that excessive stress leads to sleep problems, hormone imbalance and weight gain. 

Perhaps the concept behind adrenal fatigue is better explained by changes which occur at the receptor level as opposed to absolute changes to hormone levels in the body (7).

The good news is that if you are experiencing these symptoms you may find relief with basic changes such as meditation (8), improved sleep, changes to your diet, the use of certain supplements and other stress reduction techniques. 

So, even if you don't believe in the concept of adrenal fatigue you may still benefit from simple and healthy life changes

#2. Thyroid Gland

Your thyroid gland sits at the base of your neck and produces thyroid hormone. 

Thyroid hormone helps regulate MANY functions in the body (9), in fact, thyroid hormone imbalances may cause 30+ different symptoms depending on the individual. 

Your thyroid is most known for its ability to help regulate your metabolism through the most powerful thyroid hormone T3 (triiodothyronine). 

T3 is secreted directly from the thyroid gland but also produced through the conversion process from T4 (thyroxine). 

Thyroid related problems may be one of the most common endocrine disorders (next to insulin resistance and diabetes) with up to 10% of the population suffering from some thyroid related disease (10).

An excess of thyroid hormone (such as seen in hyperthyroidism) causes your entire body to "speed up"

Those with hyperthyroidism experience symptoms such as diarrhea, rapid heart rate, weight loss and hair loss. 

Those with hypothyroidism experience the exact opposite as their entire body "slows down"

Those with hypothyroidism may experience symptoms such as weight gain, depression, constipation, a slower than normal heart rate, a low body temperature and dry skin. 

Thyroid problems can be easily diagnosed and assessed with simple routine blood tests. 

While diagnosis remains simple, management of thyroid disease remains somewhat controversial. 

You can read more about these issues and what to do about them here

#3. Ovaries

In women, ovaries directly produce the sex hormones estradiol and progesterone (11).

These sex hormones regulate the menstrual cycle, are involved in fertility and the ability to conceive, your mood, help manage your weight, promote sex drive and support the development of female sex characteristics such as your breasts and fat deposition during puberty. 

Sex hormone imbalances, in both men and women, are becoming increasingly common. 

Conditions such as obesity promote the production of excess estrogen through aromatization (12).

Other hormone imbalances such as thyroid disease can also indirectly lead to infertility and menstrual problems through its influence on progesterone (13).

Women who suffer from sex hormone imbalances often know something is "off" in their body because they no longer feel like "themselves"

Symptoms such as weight gain (especially in the thighs and hips), changes to your menstrual cycle, bloating, cravings for foods, inability to control your mood, changes to your body temperature and so on may be early indicators that something is off with your hormones. 

Both estrogen and progesterone can cause these issues but most commonly women will suffer from an excess of estrogen and a deficiency in progesterone. 

This tends to occur primarily because excess fat accumulation on women will usually lead to excess estrogen production (and as a nation we suffer from obesity)

Unsurprisingly, perhaps, is that there is controversy surrounding how to treat hormone imbalances in women. 

Many physicians are willing to prescribe high doses of synthetic birth control pills to "shut down" the normal hormone system, but balk at the use of bio-identical hormones that your body is used to making on its own. 

This logic from conventional physicians has lead to widespread use of birth control pills for treatments such as endometriosis, PCOS and PMS when lifestyle changes such as diet, exercise (14) and some supplements may potentially help. 

You can test for both estradiol and progesterone in the blood (through routine blood tests) and you can learn more about how to determine if you have normal estrogen here and normal progesterone here. 

#4. Testes

In men, the testes help produce one of the most powerful and important male sex hormones. 

What hormone am I talking about? Testosterone. 

Testosterone is present in both men and women, but in men, it helps to control libido (15) (sex drive), muscles mass (16), metabolism, weight (17), mood, metabolic function (18), and much more. 

Testosterone is probably the single most important hormone in men when it comes to quality of life. 

This is exactly why there is such a huge emphasis on male testosterone or "low T" clinics in the United States. 

benefits of testosterone replacement therapy in men

Under normal conditions, testosterone declines as men age up until they hit age 50 or so when they reach andropause. 

Andropause is the male equivalent of menopause and both conditions result in several changes which both men and women are not too fond of. 

But other conditions can result in the premature decline of testosterone levels in men in their 20's, 30's and even 40's. 

Conditions such as weight gain (even 10-20 pounds) can prematurely lower testosterone (19).

But that's not all: 

Insulin resistance from poor diet, lack of sleep, excess stress from work (20) and a sedentary life (lack of exercise) have all been shown to prematurely lower testosterone. 

This has led many men to seek out testosterone replacement programs designed to normalize their testosterone. 

While testosterone can be a safe and effective tool in both men and women (21), you should always do your best to take care of lifestyle factors (such as weight, sleeping habits and so on) before using testosterone. 

Before using testosterone replacement therapy you can also look into certain supplements designed to naturally improve testosterone

#5. Hypothalamus

This small gland is found in your brain where it sits next to the pituitary gland. 

The hypothalamus serves to communicate almost directly with the pituitary gland to help regulate almost all of your hormones at a central level. 

The hypothalamus also helps to regulate your appetite, metabolism, sexual desire and emotional responses. 

It does this by sampling your blood for certain metabolites and then by relaying that information to the pituitary where it can stimulate the release of certain hormones. 

You can think of the hypothalamus as one level higher than the pituitary gland. 

I'm not going to include all of the hypothalamic pro-hormones in this area but you can read more about them here

Just realize that your hypothalamus is pumping out hormones designed to help increase testosterone, estrogen, progesterone, cortisol and thyroid hormone

Hypothalamic function can be altered and suppressed by factors such as an unhealthy diet, excessive exposure to stress, lack of sleep and even lack of exercise. 

Because of its importance in the regulation of MANY hormone systems, poor lifestyle can cause a dramatic impact in your quality of life if it suppresses hypothalamic function. 

#6. Pituitary

The pituitary is often referred to as the "master gland" because its main job is to produce pro-hormones which cause the release of pretty much all of the other hormones we've discussed so far. 

This gland is in your brain and secretes a bunch of "stimulating" hormones which find and act on target tissues to stimulate the release of hormone. 

Your pituitary gland is constantly sensing your blood for hormone levels and it responds by either increasing the amount of stimulating pro-hormone or by decreasing it. 

In this way, it can help regulate all of the hormones we've discussed by acting as a "central computer" for your body. 

Here is a list of some of the stimulating pro-hormones produced by the pituitary gland: 

  • FSH (Follicle-stimulating hormone) & LH (Luteinizing hormone) - FSH and LH stimulate the ovaries and testes to produce sex hormones such as testosterone, progesterone and estradiol (22) and sperm production (in men). Both men and women have FSH and LH in their body where they serve to help control sex hormones. 
  • ACTH (23) (Adrenocorticotrophic hormone) - Stimulates your adrenals to produce cortisol. 
  • TSH (Thyroid stimulating hormone) - Stimulates the thyroid gland to produce thyroid hormones both T4 and T3. 
  • Prolactin - Stimulates the breasts to produce milk. 
  • GH (Growth hormone) - Growth hormone helps to both grow and repair tissues in your body. Growth hormone during puberty helps the body grow and GH is hypothesized to play an important role in the aging process in adults (24).

Suppression of these hormones can be caused by trauma (seen in many people who have previously served in the military oversea's (25)), infections, tumors, certain medications, extreme dieting and so on (26).

Any problem with your pituitary gland will often result in large changes to MANY hormones in your body. 

These pro-hormones can be easily assessed through routine blood work. 

#7. Pineal Gland

The pineal gland is a small pinecone-shaped gland found near the center of your brain. 

It's most well known for its secretion of melatonin (27) which is a hormone designed to help regulate your sleeping patterns and your circadian cycle. 

Chronic stress, exposure to blue light from computer screens, disturbances in other hormones and travel can cause dysregulation in the secretion of melatonin. 

Small disturbances may manifest as difficulty falling asleep, staying asleep and waking up feeling restful. 

Melatonin is available over the counter and can be used as supplement for very specific conditions to help with sleep, but it should generally only be used temporarily. 

It's important to remember that, even though melatonin is available over the counter, it is still a hormone. 

#8. Parathyroid Gland

Your parathyroid glands are found behind your thyroid and they help to regulate both calcium and phosphorus. 

There is also a connection between Vitamin D and the parathyroid gland (28) which may play a role in Vitamin D deficiency and other disease states (such as autoimmunity) related to Vitamin D status. 

Most people do not have issues with their parathyroid glands unless they develop a tumor or they are damaged during thyroid surgery (such as thyroidectomy). 

#9. Thymus

Your thymus gland is important in creating and educating white blood cells that help your body determine the difference between foreign invaders and "self" (29).

This organ is found in your chest but it starts to shrink and atrophy after puberty. 

#10. Pancreas

Your pancreas is found in your abdomen and plays an important role for both your digestive system and your endocrine system. 

For the digestive system, it secretes pancreatic enzymes which help break down your food, kill off bacteria that you may consume and help keep your intestinal microbiome healthy. 

Overt damage to the pancreas can occur through the consumption of alcohol, trauma and certain medications. 

Other people may endorse difficulty digesting foods owing to differences in each person and their ability to secrete pancreatic enzymes. 

Some individuals just have an easier time digesting food when compared to others and this difference may be explained through pancreatic function. 

People who suspect they have an issue with digestion can take over the counter pancreatic enzymes to help improve their digestion and improve GI related issues (30).

But that's not all the pancreas does. 

It also secretes two very important hormones known as Insulin and Glucagon. 

Together, these hormones help to regulate your blood sugar. 

When you eat food your body responds by increasing insulin secretion to help take the food that you consume and store it as energy for later use. 

Overstimulation of insulin secretion, through sugary foods and carbohydrates, can result in a condition known as insulin resistance (31).

This is a condition where your body develops a resistance to the hormone insulin which requires higher and higher levels to be secreted. 

If you get to this point you may start to experience diabetes as your body is no longer able to keep blood sugar levels in check. 

Before you develop diabetes, however, there is always some degree of minor insulin resistance (remember hormone imbalances exist on a spectrum!). 

Minor insulin resistance can make your weight loss efforts more difficult (32) and lead to an increase in abdominal fat, cholesterol issues and other metabolic problems. 

Catching insulin resistance early, and treating it with lifestyle therapies (such as diet, supplements and exercise) can prevent diabetes from developing and help you stay healthy. 

You can learn more about basic and advanced therapies to treat insulin resistance here


Hormone-related issues are becoming more and more common and much of this may have to do with problems in the endocrine system. 

Understanding the basics of this system will help you become an advocate for yourself when you have discussions with your doctor. 

If you are having any issues in your endocrine system it may manifest as changes to the symptoms we have listed above. 

Don't accept aging or the fact that you are getting older as a cause for these symptoms. 

It is possible to maintain healthy and youthful levels of these various hormones as you age through a healthy lifestyle

Now I want to hear from you: 

Do you suspect you have an endocrine-related issue?

Are your hormones changing as you age?

What symptoms are you experiencing?

Have you had luck in getting treatment from your doctor?

Leave your comments below! 

References (Click to Expand)

patient guide to the complete endocrine system

Dr westin childs photo

About Dr. Westin Childs

Hey! I'm Westin Childs D.O. (former Osteopathic Physician). I don't practice medicine anymore and instead specialize in helping people like YOU who have thyroid problems, hormone imbalances, and weight loss resistance. I love to write and share what I've learned over the years. I also happen to formulate the best supplements on the market (well, at least in my opinion!) and I'm proud to say that over 70,000+ people have used them over the last 6 years. You can read more about my own personal health journey and why I am so passionate about what I do here.

P.S. Need more help? Check out my free thyroid downloads and resources.

17 thoughts on “A Patient Guide to the Entire Endocrine System: Hormones, Glands & More”

  1. Dear Dr. Childs,

    I just wanted to say that your comments and advice are always to the point!
    I have been following your advice lately without realizing it; I have simply chosen to eat more of the food that makes me feel well and satisfied for longer, while cutting back on food that doesn’t…unlike some, I don’t feel well on large amounts of meat, especially red meat, so I tend to favor chicken or fish instead. Lately, I have not cared about how much olive oil, rapeseed oil, or virgin coconut oil I consume, but rather used as much as I needed to make my meals tasty.
    Eating this way has enabled me to lose 28 kilograms (ca 62 lbs) in the past six months, without much effort. I exercise regularly but don’t go jogging for a couple of hours a day either.
    This is by far the most effective weight loss method I’ve used so far, even though I did not follow a specific diet plan but rather asked myself: what makes me feel good and what doesn’t? But, the single most significant benefit from all this has been not being afraid of good fats. While it may be true that all fats contain the same amount of calories, they obviously affect us very differently. I have cut back on butter and trans fats in favor of olive and rapeseed oil along with extra virgin coconut oil. I also eat an avocado a day…something that would have been unimaginable back in the good or rather bad old “avoid fat at all cost” days…and it seems to be working like a charm!
    I have often benefited from your advice in the past, and think you are one of the most reasonable doctors I know of. Your advice is always to the point and, equally important, not difficult to follow at all. You recommend small but significant changes that anyone can easily implement, and that is also important as I know from personal experience that changes need to be reasonable in the long run, or we tend to give up and go back to our old bad habits…
    So, please keep up the good work; I’m looking forward to reading more of your very interesting and enlightning articles in the future!
    Kind regards,

    • Hi Anna,

      Thanks for sharing your story and congratulations on the weight loss! Also, thank you for the kind words 🙂

  2. Hi Dr. Childs,

    Question? I had a partial hysterectomy about 1 year ago & I am now gaining weight uncontrollably even with diet & exercise. My Dr. said my hormones & thyroid levels are normal but I know there is something going on with my hormones because my face is also breaking out like never before. And I have never had skin issues before. Do you think your products can help?

    • Hi Michelle,

      It’s too hard for me to say without more information. Most endocrinologists and Doctors don’t really understand hormones so they always say they are “normal”, but it’s fairly easy to determine they are not normal especially in the face of the symptoms you have described here. But which hormones are abnormal is the hard part to discern with limited information.

  3. Dear Dr. Childs,
    I’m so glad I stumbled across your website!
    I’ll try and make this short.
    I am 57 years old post menopause (natural)
    In 2016 while getting a Cervical and Lumbar MRI it was found that I have mild fullness in my left Adrenal gland. I was referred to an Endocrinologist who ordered a follow-up MRI w/wo contrast and there were no changes. He also ordered a 24-hour urine test which came back negative.
    I also saw a new PCP in 2016, who ordered labs I had low D3, slightly abnormal Cholesterol levels and otherwise normal labs including T3&4.
    Newer labs in 2017 showed slightly abnormal T4 another MRI showed no Adrenal changes (I get an MRI every 6 months)
    My latest labs show normal thyroid, but TPO Ab is 232.
    I asked for the Ab test because my sister about 6months ago was diagnosed with Hashimoto disease after being on Synthroid for 30 years, my mother has been on Levothyroxine for 20years and was also recently diagnosed with Hashimoto.
    In addition, I was diagnosed approx 10 years ago with Fibromyalgia, Dr’s say I’ve probably had it since I was about 10 years old. And I have numerous health problems, blamed on the Fibro. IBS both C and D, Chronic widespread pain, Angina, Costochondritis, and other odd complaints!
    I’m sure hoping you can advise me prior to my follow up next week!
    Thank You very much!

  4. Dr. Westin,
    I am thrilled to have stumbled across your website!

    Q Well based on my situation and reading your recommendation should I push for thyroid medication if they say it’s not currently necessary?
    I have numerous symptoms of thyroid issues.

  5. Hi, Dr. Childs!
    Can you take liver support supplements (milk thistle, burdock root, dandelion root…) while taking levothyroxine? Maybe this herbs can lower the efficacy of the med because of their cleansing properties?
    Or is it ok to take levo in the morning and the others at night?

    Thank you!

  6. Hi Dr. Childs,

    My question is about a 23 year old male who is on testosterone replacement therapy due to low levels of testosterone. His most recent blood tests came back showing elevated levels of total and free testosterone yet he feels good and has absolutely no symptoms of elevated T levels. He feels unwell emotionally and physically if he lowers his dose so it seems he needs his current dose to function optimally.

    Is this possibly a case where one can go by symptoms and not pay as much attention to the labs or are elevated blood levels of testosterone (1900 Total, 500 Free and verified by repeat testing) always a cause for concern? Are there times where the testosterone can pool in the blood and it’s not as high in the cells? I’ve never heard of that before but I thought it might be a reason why the tests show high but there are no symptoms of high testosterone.

    He recently lost 90 pounds using your program and has started working out and feels great (except for the worry about the blood test results.)

    His doctor gave up on him, saying his case is too complicated so he’s trying to find another doctor but in the mean time he’s trying to figure things out on his own and I’m trying to help. Thanks for any light you can shed on this type of “high testosterone levels but no symptoms of it” situation.

  7. Hi!

    So awesome to come across your site!
    I am a 35 yr old woman that has for the most part been a healthy person, exercising routinely and just eating healthy foods.
    But around 4 yrs ago I started experiencing sleepless nights, hot flashes, night sweats, mood changes, low libido and weight gain… weight that despite how much I exercise and try to eat healthily I can’t lose. It is very frustrating. The not sleeping due to the hot flashes are horrible!
    I finally made an appt with an endocrinologist, which is in a couple of days. I was wondering if perhaps you can give me an idea of what I should bring up in the discussion with the doctor to get the most out of this appt.
    Thank you so much!

    • Hi Alex,

      The best thing you can do is to look for a comprehensive analysis of all of your hormones and not just one or two. You should be checking your estrogen, progesterone, thyroid hormone, and testosterone levels. You’ll find, though, that endocrinologists are usually not the best physicians to use when evaluating for these problems.

      • Oh no! Really? Why not? Should it be my primary doctor? I thought that maybe an endocrinologist would do more of a thorough test. Should I cancel that appointment?
        I’m confused.
        Thank you for your prompt response!

        • Hi Alex,

          It depends on what you are looking for, but medicine has become segregated and most conventional physicians don’t know much about hormones in general. Endocrinologists focus usually on diabetes and hypothyroidism and the integrative doctors tend to do more with hormone replacement therapy.

          This article will help explain what I am talking about in more detail: https://www.restartmed.com/thyroid-doctor/

  8. Dr Childs,

    Brief Background:
    – Sex: Male / Age: 33 / Height: 6’1 / Weight: 116kg (255 lbs)
    – Current BF%: 28% (from 33.1% at April 2019)
    – 1 of 3 brothers (youngest of 3)
    – Only one with obesogenic tendency (both brothers fairly lean)
    – Had reached weight of 280lbs by age 15
    – Fat distritbuion mainly around lower back / thighs (never “beer belly” that protrudes outward)
    – Always been fairly active (played loads of sports growing up)
    – Currently gym it about 3 times a week and do a combination of HIIT rope work and Olympic Weightlifting (think Power Snatches /
    Clean & Jerk / variations)
    – Play amateur golf at a competitive level
    – Weight has been stuck in current place (between 250lbs – 260 lbs) over the past 5 months
    – No diabetes in the family

    Diet History
    – Did the “South Beach Diet” for a few weeks at age 15
    – Have been on-off Low Carb over the past 15+ years
    – Only time I was able to go below 200lbs was durung a 90 day zero carb low calorie approach (during the latter 30 days was struggling to keep temperature)
    – Currently alternating between Keto and Carnivory (keeping calories between 2,000 to 2,500 around my “maintenance” level – sometimes higher during very active gym / outdoor days)
    – Thinking about upping carb count a bit via certain fruits (bananas / dates) to see if that “resets” anything

    Current Labs (July 2019)
    TSH: 1.34
    Free T3: 3.03
    Reverse T3 (Feb 2019): 119
    Fasting Insulin: 21.7
    Fasting Glucose: 108
    HbA1c: 5.6
    Total Test: 611.5
    Estradiol: 22.00
    SHBG: 24.3
    Cortisol (AM Fasted – Blood): 9.3
    Prolactin: 6.30
    DHEA-S: 300.9
    Other: Cholesterol and liver markets are OK (liver optimal / cholesterol on the high side of normal)

    Observations / Notes
    – Fasting Insulin of nearly 22 is a big alarm bell
    – Fasting blood glucose is on the high side (can happen / fairly typical in the low carb community especially amongst physically active individuals)
    – Currently on TRT Therapy (was on the low side of 300s) in early February
    – Body composition improving (reduction of BF% – think TRT helping quite a bit in this regard) however weight itself remains fairly stagnant
    – TRT for me is and remains just a temporary measure to assist in optimising my hormonal profile (doing it with a hollistic Doc)
    – My hollistic Doc keeps pressing for Intermittent Fasting and Keto, which often causes me to have low libido (and mild ED) in spite of the TRT therapy
    – Once I up my carb intake a bit then libido and ED issues tend to disappear / normalise
    – As a recently wed, young, married male I do not want to have issues in the bedroom with my wife
    – I also want to tackle my weight issue(s) once and for all for both overall health and athletic purposes (I compete at a faily high level on the golf bit I wrote earlier)

    Am trying to solve for:
    – Reducing Fasting Insulin
    – Maintain bedroom performance

    Thoughts on nutritional approach / general thoughts / ideas would be very much welcome. Happy to pay for online consulting / 1-on-1 if better medium.

    I appreciate quite a bit of your posts are geared towards a more female-centric audience (who statistically have more thyroid issues than men) however I fhave ound a few of the posts that you have covered on male obesity to be quite helpful.
    Appreciate your content very much.


  9. Hi Dr. Westin Childs,

    I have searched your page various times to see if you had any opinion or information on growth hormone therapy, but I failure d to find any. . I have been on and off growth hormone and use Egrifta during times I do not use growth hormone. Subjectively speaking, I feel much better on growth hormone, pain, cognitive function, depression and anxiety symptoms greatly improve. I don’t have depression or anxiety, but I feel as though I do when I go off growth hormone. I was wondering if you had thoughts on GHD and therapy as it’s contradicted with insulin resistance. Do you believe growth hormone can be used long-term for an optimized metabolism?

    I’ve recently been using semaglutide for insulin resistance alongside acarbose, which has been great for my microbiome and corrected my IBS. I do notice that acarbose causes joint pain, but does not when I use growth hormone. I am concerned it’s blocking IGF-1 from binding to the receptor sites. Do you have any thoughts on the above?

    I would like to take metformin, but I am very concerned of the negative effect on exercise. Do you have any thoughts of this?

    I love your work, I refer to your articles often, great information and very thorough.

    I appreciate your response I’m advance!

  10. Hello Dr. Childs,

    Could you help me understand the connection between vit D, calcium and parathyroid better?
    My 17-year old daughter has a thyroid nodule which recently increased in size slightly (1.7cm x 1cm from 1.4cm x 1cm in February). We’ve done two biopsies in Feb, and both showed mixed results and couldn’t confirm or deny whether it’s benign or malignant. After the second biopsy, some of the material was sent to Thyroseq, a genetic company specializing in thyroid gene sequencing. The results came back negative, meaning the chance of it being cancerous are < 3%. This was somewhat a relief but did not tell us much more.
    Recently, we did more tests, and her PTH came up high – 65 pg/mL. Also, her serum calcium levels have been high -around 10 mg/dL, and her vit D is very low – it was 25 ng/mL in January, and after a year of supplementation it is now 20 ng/mL.
    Could this mean she has a parathyroid issue or nodule, and how is this related to her thyroid nodule? What is the relationship between calcium, vit D and her parathyroid? Trying to understand the root cause so we can better address the issues.
    Any help is greatly appreciated! Thank you!


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