- After thyroidectomy, you'll likely gain 20-30 pounds as a new baseline unless you proactively manage your thyroid medication and hormones, making proper replacement critical from day one.
- Total thyroid removal creates a more challenging weight loss scenario than autoimmune hypothyroidism because your body cannot produce any thyroid hormone on its own, requiring higher external replacement doses.
- Standard levothyroxine-only replacement after thyroidectomy fails to achieve weight loss for most patients. You typically need combination T4 and T3 therapy at higher doses to match lost metabolic capacity.
- Patients who gain less weight post-thyroidectomy consistently use T3 supplementation, optimize other hormones (insulin, cortisol, sex hormones), and maintain lean muscle mass through strength training.
- Weight loss after thyroidectomy is possible but requires patience and physician collaboration. Expect 1-2 pounds per week maximum, and plan for 6-12 months of treatment adjustments before reaching your goal weight.
Almost every patient gains weight after having a thyroidectomy.
In fact, it’s considered normal to gain 20-30 pounds and most doctors just shrug it off as “normal”.
When you consider that thyroid hormone controls the metabolism of your entire body and that after removing it most patients gain 20-30 pounds, shouldn’t we at least consider that something is wrong here?
Maybe our current treatment recommendations might be flawed.
It just seems logical, right?
I hate to break it to you, but most doctors don’t think twice about it. And there aren’t a lot of resources for patients after they get a Thyroidectomy.
But here’s the deal:
Patients who have had a total thyroidectomy deserve special attention because their situation is unique, and they shouldn’t be treated like all other thyroid patients.
Luckily, there are some tips and tricks you can use to help with weight loss after thyroidectomy and I’m going to share them with you here…
Why Do Patients Gain Weight After Thyroidectomy?
It’s well known that many patients (especially women) gain weight after having their thyroid removed.
In fact, it’s been shown that women who have a total thyroidectomy gain more weight than patients with hypothyroidism (1).
And, let’s face it:
Most Doctors don’t do a good job of treating hypothyroidism, otherwise, websites like this wouldn’t exist!
And, following the trend, doctors typically do an even worse job in treating post-thyroidectomy patients.
Let’s take a minute and talk about weight gain after thyroidectomy.
Why are patients gaining so much weight?
The truth is that regulating hormones is very complex.
The thyroid system in your body is no exception.
And the medical world doesn’t have a great track record in balancing and regulating hormone levels.
Take for instance Type I Diabetes:
Medicine has developed near-continuous blood glucose monitoring systems and we still don’t do a great job of controlling blood sugar (2).
Now compare that to your thyroid.
How often are you getting your labs tested? How often is your medication being changed? Are you feeling any better about those changes?
It might be time to make a change to our current treatment paradigm, or at least consider the fact that we don’t have it all figured out.
In order to understand why our current treatment doesn’t work, we have to understand why we actually gain weight…
Weight Gain is Not About Calories
Weight gain is not about eating too many calories or not exercising enough. Period.
It’s about an imbalance in your hormones.
How else do you explain the sudden weight gain in post-thyroidectomy patients despite eating the EXACT same foods before and after?
Or how about the weight gain associated with menopause (3)?
Do these women just happen to magically start eating more and exercising less at the precise time their estrogen levels drop (in the case of menopause) or their thyroid levels drop (in the case of thyroidectomy)?
Obviously not.
Weight gain is a hormonal problem!
And to fix it we have to fix the hormonal imbalance.
Unfortunately, the current paradigm is set to make you believe that in order to lose weight you must eat less and exercise more.
You even get this kind of advice from places like the Mayo Clinic (4) and Livestrong…
This is bad advice, so please don’t follow it. (Check out this post on nutrition facts that should be common sense but aren’t for more info)
In fact, reducing your calories has been shown to reduce your overall metabolism, and may make your thyroid function even WORSE (5).
Dieting leads to low levels of Free T3 and higher Levels of Reverse T3 which means you’re going to slow down your metabolism even more.
I know what you’re thinking:
I don’t have a thyroid and I take medication so it doesn’t matter to me.
Not true at all.
If you’re on T4 medication your body must convert it to the active Free T3 in order for it to work.
And your body can still turn it into Reverse T3 as well.
So it definitely still matters to you.
What about Diet after Thyroidectomy?
The truth is that diet is still important for weight loss in Thyroidectomy patients, but not as you think.
I don’t want you to think you need to restrict your calories to lose weight (that won’t work).
But it is still important for you to eat a HEALTHY, nutritious, and whole-food diet.
If you don’t know what that is you can find a lot of information about it here.
And, to answer your question, yes it will work for patients with a sluggish thyroid and for those without a thyroid.
So in addition to eating a whole food diet, what other things will help with weight loss after thyroidectomy?
Let’s jump into some tips that can actually help you lose weight if you no longer have a thyroid.
1. Get On the Right Type and Dose of Thyroid Medication
This is a critical step and the first place I recommend you start. (It can also be the toughest part because it requires a doctor to prescribe you the RIGHT medication)
As I’ve mentioned before your thyroid controls the metabolism of your body.
And currently, we have an epidemic of thyroid patients that are being undertreated.
To understand why this is you need some basic understanding of thyroid physiology:
There are 2 main types of thyroid hormone that your doctor can prescribe.
T4 = The inactive thyroid hormone <— This is what most Doctors prescribe and very few people do well on this medication (Yes I said that it is inactive by itself)
T3 = The ACTIVE hormone <— Most people do better on this medication (6) but most Doctors don’t prescribe medications containing T3
For more information on thyroid medications check out this post here.
Most people do better on medication that contains the T3 hormone and studies show this to be the case.
Patients on Natural Desiccated Thyroid hormone (a medication that contains T3) lose more weight and have better satisfaction than patients on levothyroxine (the medication you are most likely taking).
Why is this?
It turns out that your thyroid produces both T4 and T3 medications (when it’s functioning normally).
It produces about 80% T4 and about 20% T3 (7).
When your thyroid is gone most patients are given T4 medications ONLY (remember that this is the INACTIVE hormone).
As a result, most patients develop weight gain and symptoms of hypothyroidism.
So what can you do?
Whenever possible I recommend attempting to mimic nature. That means dosing your thyroid with 20% T3 and 80% T4.
If your doctor is willing to work with you, you have a couple of options:
Get on Natural Desiccated Thyroid Hormone which contains roughly around an 80/20 ratio of T4 to T3 – in addition to other less biologically active thyroid hormones.

Add Cytomel or liothyronine to your dose of T4 – Let’s say that you are currently on 100mcg of T4. In this case, I would simply add 20-25mcg of T3 medication to your regimen (note: you may need more or less depending on how sensitive you are to this medication).
Adding T3 medication to your regimen can drastically improve your overall symptoms and metabolism thus leading to more weight loss.
And remember:
After thyroidectomy, the ONLY way you are getting T3 is in the form of medication.
2. Optimize your Free T3 Levels
Under normal circumstances, your body must produce free T3 from T4 (unless you provide T3 directly via medication).
The problem is that your body can also turn T4 into Reverse T3 which is a thyroid blocker (it sits on free T3 receptors on the cells and blocks the action of thyroid hormone).
Because of this, it is important to optimize this system and make sure your body is producing as much free T3 as possible and as little reverse T3 as possible.
I’ve gone into a lot of detail on how to increase your free T3 levels naturally in this article, but I will also go over some useful info here as well.
In order to optimize free T3 levels you will want to do the following:
- Take supplements that increase T4 to T3 conversion like zinc, selenium, and B6
- Get off of medications (if possible) that block (8) T4 to T3 conversion like antidepressants, narcotics, mood stabilizers, pain modulators, blood pressure medications, and diabetic medications. You can find an entire list of supplements and medications that interfere with thyroid function here.
- Heal any digestive issues you may be dealing with like acid reflux, bloating, or irritable bowel syndrome – use a high-quality multi-strain weight loss probiotic.
- Make sure your iron levels are in the “optimal range” (more info in this article here)
- Reduce inflammation in the body (high levels of inflammation promote reverse T3 production)
Bottom line:
Higher free T3 levels = Higher metabolism = more weight loss
Increase these levels naturally with supplements or artificially with medications, but either way, you will want your free T3 levels as high as possible (but still within natural physiologic ranges).
3. Balance ALL Hormonal Systems in the Body
Balancing your thyroid is just one piece of the weight loss puzzle.
In fact:
I’ve never seen a thyroid patient with just ONE hormonal imbalance, and patients with weight loss resistance tend to have several.
And it’s also important to remember that hormones interact with other hormones!
For instance, thyroid hormone interacts with progesterone (9), cortisol (10), and insulin levels (11).
This is especially true in patients without a thyroid.
To make your weight loss efforts MOST effective you will want to evaluate the following hormones:
- Insulin Levels – High levels of insulin (AKA insulin resistance) cause weight gain in the belly. More info here.
- Estrogen Levels – High levels of estrogen and low levels of progesterone promote weight gain in the hips/butt and thighs.
- Testosterone Levels – Low levels of testosterone cause depression, weight gain, and reduced muscle mass.
- Leptin Levels – Leptin resistance causes increased appetite, low metabolism, and chronic weight gain. Find out how to reverse it here.
- Cortisol – Adrenal fatigue leads to weight gain in the belly, reduced energy, and inability to tolerate stress. Almost EVERY thyroid patient has issues with cortisol.
Use the following guides to help balance these hormones:
- Learn how to use progesterone safely and correctly for weight loss here
- Learn how to use powerful supplements such as Berberine and Alpha lipoic acid to help with weight loss and improve insulin signaling
- Learn how to deal with Testosterone and DHEA here
- Learn how to lower Leptin levels with targeted supplements here
I’ve included a table below that will teach you what tests to ask for and how to determine if your hormones are out of balance:
4. Be Strict with your Diet but Don’t Restrict Calories
When I use the word diet I am referring to the food that you eat.
I’m not referring to DIETING or eating a calorie-restricted diet.
In fact, eating a calorie-restricted diet will actually make your thyroid function worse (12).
Since we’ve already discussed diet in this article I won’t go over it much more except for some general guidelines:
- Stick to Organic Food groups and Grass-Fed/Organic Meats
- Don’t be afraid of eating Healthy Fats
- Eat lots of Vegetables
- Don’t snack every 2-3 hours
- Avoid Processed foods or anything that comes in a box or package
- Avoid sugar and artificial sweeteners as much as possible
5. When your Energy Improves make Exercise Count
It may be difficult to think about exercising when you are suffering from fatigue after your thyroidectomy (another sign that you are being undertreated), but I can’t underscore how important exercise is for your health.
Exercise isn’t important because you are “burning calories”.
It’s important because it helps to balance hormones in your body (13), release endorphins (14), and stimulate neurotransmitter release (15).
Even if your energy levels are low, I recommend that you start with low-intensity exercise on a daily basis:
That can be walking for 30 minutes per day.
Once you have a handle on low-intensity exercise, you can then start to add in slow-weight training and high-intensity exercise.
These types of exercise have been shown to be more effective than traditional “aerobic” exercise and have the additional benefits of building muscle mass and taking up less time than standing on a treadmill for hours.
Putting it all Together
I know that it can seem impossible to lose weight after thyroidectomy, but let me tell you that it IS possible and I’ve helped MANY patients do it.
It just takes a systematic approach and a sympathetic physician.
Because getting on the right type and dose of thyroid medication (preferably medication that contains T3!) is so important I recommend that you find a Doctor who is willing to work with you.
In addition, you will need to find someone who will look at your other hormone levels and treat them appropriately.
The other aspects: Diet, exercise, lifestyle changes, and supplements/vitamins – are things that YOU can take care of.
Also, remember that healthy weight loss may take months to achieve. But once you are able to lose pure fat mass without losing muscle mass, your weight loss will be long and lasting.
Now I want to hear from you:
What have you done to lose weight after your thyroidectomy?
What has worked, and what hasn’t?
Was changing your thyroid medication helpful?
Leave your comment below!
Further resources:
Weight changes in euthyroid patients undergoing thyroidectomy (16).
Weight changes in patients with thyroid cancer after thyroidectomy (17).
Weight gain in hyperthyroid patients after thyroidectomy (18).
More studies show weight gain in hyperthyroid patients after thyroidectomy (19).
Scientific References
#1. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229816/
#2. http://www.ncbi.nlm.nih.gov/pubmed/8299480
#3. http://www.ncbi.nlm.nih.gov/pubmed/22978257
#4. http://www.mayoclinic.org/healthy-lifestyle/weight-loss/basics/weightloss-basics/hlv-20049483
#5. http://www.ncbi.nlm.nih.gov/pubmed/6771066
#6. http://www.ncbi.nlm.nih.gov/pubmed/23539727
#7. https://www.ncbi.nlm.nih.gov/books/NBK499850/
#8. https://www.ncbi.nlm.nih.gov/pubmed/20578900
#9. http://www.ncbi.nlm.nih.gov/pubmed/9846161
#10. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520819/
#11. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356957/
#12. https://www.ncbi.nlm.nih.gov/pubmed/12055988
#13. http://www.ncbi.nlm.nih.gov/pubmed/10683091
#14. http://www.ncbi.nlm.nih.gov/pubmed/6091217
#15. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077351/
#16. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229816/
#17. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595360/
#18. http://www.ncbi.nlm.nih.gov/pubmed/24522995
#19. http://www.ncbi.nlm.nih.gov/pubmed/11531931

Hello Dr. Childs,
I had a partial thyroidectomy after my doctor found a nodule that turned out to be a papillary carcinoma. I am on Synthroid 0.05 mg. I am just wondering if your information also pertains to partial thyroidectomies? I have noticed my weight creeping up since my surgery 5 years ago. I am 49 and premenopausal.
Hi Mary,
Yes, the information still applies to you 🙂
Hi Dr Childs
Are you taking new patients?!
I’ve had a tt at the end of last year and am now on 125 Tirosint having fought really hard to get it – I have MCS and actually felt suicidal.
It suits me far better than the generics and Armour but I feel lardy despite not changing my diet etc.
If I can’t see you, is there anyone you’d recommend I see in the UK who won’t leave me bankrupt?
Thank you
Hello my name is Janelle. I had my thyroid completely removed 14 years ago because I had Graves Disease and a goiter. Because of the surgery I have problems with my calcium levels which are always low and now I have a vitamin D deficiency. I am on 150 mcg Levothyroxine and 5cg Liothyronine. My labs come back normal but I always feel horrible. I am in constant pain from my feet to my thighs and my weight will not drop. I always stayed at 160-170 pounds but after I turned 40 I am at 219. I work out and eat very little I even fasted a few times and all I could get to was 210 pounds. It is almost like my body refuses to loose any more weight. I have no idea what to try next. I am constantly constipated and the only time I felt normal was hen I was taking Ali diet pill which made me regular feel better and I could loose more weight. My doctor told me not to take it anymore but wont listen to me when I say I feel bad everyday. Is there any other vitamins I can take for the leg and feet pain? I am also scared to eat more because I feel like my body wont burn it.
Hi Dr Childs
Thanks again for your articles. Would you recommend intermittent fasting of any sort for thyroidectomy patients on NDT?
Many thanks
Hello Dr. Childs,
I had a total thyroidectomy in April 2022 and gained about 15 pounds till today (June 2023). After the surgery I felt fatigue and less energetic but I still tried to remain exercise about 3 times a week (I played 3 hours of badminton once a week which is really tiring and very sweaty after the games). I tried to eat less but the weight still gained over time and I felt really frustrated. I am in Taiwan so no T3 medication is available here at hospital or clinic. I wonder if I order “raw thyroid” supplement online and take it with my sinthyroid medication, will it help me with my weight gain? Any other suggestions will be highly appreciated, thank you. 🙂
I noticed the swelling on my neck about twelve years ago. It was tested by an ear, nose, throat doctor and it was not cancerous. I am now 82, the swelling is larger, but no sign of cancer through ultra sounds. My doctor has suggested surgery. I do not want the weight gain at this age – would it be a good choice to skip the surgery? At this point, I have not been taking any medication, and at my age, I’m thinking I might do best to skip surgery and carry on with my life, which is out-going. Any thoughts?
Hi Virginia,
I would get some more information from your doctor and ask why they think thyroid removal is necessary. If their reason isn’t sufficiently convincing then you may be able to hold off and try natural therapies to see if they can improve your situation.
Hello Dr. Childs,
I had my TT in 2010 with RAI-131. I don’t remember gaining much weight in the beginning, but in the past 3 years or so I have gained weight. When I gain 1 more pound I will be at the weight I was when I gave birth to my daughter, 52 years ago when I weighed 132 lbs. I can’t fit into most of my clothes anymore and my gut looks like I looked when I was 9 months pregnant.
Why did it take so long for me to start this weight gain journey?
Thank you, Rhonda
Hi Rhonda,
Most likely, it was likely triggered with hormone changes to estrogen and progesterone which occur around menopause. Both of these hormones can influence thyroid function and lead to weight gain when out of balance. That’s just a guess, though, because there isn’t enough information to say for sure.
Thanks, Dr. Childs for your response. I had a total hysterectomy in 1995 and TT in 2010. Not so sure that menopause has much to do with it and I should have provided that information.
Lately, I’ve read many of your responses regarding many issues and you keep saying Total Thyroidectomy patients are different and should be treated differently, but I haven’t found any information on your blogs that explains what that really means. Why are patients who’ve had a TT different than people with hypothyroidism for other reasons? I understand the obvious, I don’t have a thyroid, and other people with hypothyroidism have different causes such as Hashi’s.
Why should I be treated differently? Do you have a blog on this topic that goes into detail? I had papillary cancer and RAI-131, does that make me different?
Hi Rhonda,
For the most part, the treamtent is the same for all causes of hypothyroidism. The primary difference for those without a thyroid is that they tend to require higher doses of thyroid medication and combination thyroid hormone replacement therapy with T4, T3, T2, etc.
I keep reading your articles over and over and the main piece of information I get is the gaining of weight. I mentioned that I also had RAI-131. I have had nothing but trouble with dry mouth, dry eyes, dry skin, DRY everything. My frustration lies in the fact that doctors & dental practitioners don’t take this seriously. I’m about to have my teeth extracted with dentures put in my mouth. Why, because RAI-131 ruined the majority of my teeth. I even went to an ENT to make sure it would be okay for this procedure, well, he said, you do have a little bit of saliva, I went to see him because of his experience working with patients like me. But he was in a bit fat hurry. Now because of all of the antibiotics I’ve had to take over the past few months while my regular dentist has filled cavities, etc. I have a yeast infection primarily in my mouth, on the tip of my tongue, and the inside of my checks and I can’t get a straight answer. I’ll just have to wait until I go in for my appt. and see what he has to say before he puts me under, extracts the rest of my teeth, and then inserts the dentures.
As you can probably tell, I am stressed and angry that these people tell me they know all about RAI-131 when in fact they don’t.
I feel you Rhonda
Same here
Hello Dr. Childs,
Update: Last Friday I had my teeth extractions completed, and the dentures put in my mouth. During the procedure, my blood pressure sky-rocketed I was given Esmolol to bring it down. By the end of the procedure, they could hardly wait to get me into the wheelchair and out to the car. I’m sure that had to do with the fact that the bottom dentures fell out. Then came the chest and left arm pain. Since I have had an MI in the past, I am somewhat familiar with this pain. My daughter was scared to death. Due to the stress, elevated BP, and my dentures falling out I think I was beyond stressed. We finally got home, I took my pain meds and got some sleep. That helped the chest and arm pain, although I still have a fluttery heart. I did not have high BP when I went in for this surgery and now I’m having a difficult time getting it back to normal using my BP medications.
The first time I had surgery for some extractions, the surgeon texted me the next day to ask how I was doing. I haven’t heard a word from their office, NOT one word after this debacle.
Another example of those in the medical profession not knowing what they are doing, not bothering to double-check my history, and telling me I could take my thyroid meds with a “sip” of water. A SIP of water? Whatever!
Please remind those who are going to have RAI-131 about the horrible things it does to the entire mouth, gums, and teeth. This has been a horrible experience!
Dear Dr Childs.. Please need your feedback.. I had thyroid cancer 7 years ago and was put on Synthroid.. I have never felt well. Finally saw a dr who put me on Armour 60mg 6 weeks ago and do feel better.. but my TSH jumped from 1.2 to 14.5! What are your thoughts to ask my doctor? Please need guidance… Should I ask if a higher dose is necessary? Please let me know.
Thank you
Marie
Hi Marie,
A jump in your TSH likely indicates that you just need more medication or that you aren’t absorbing what you are taking.
My thyroidectomy was in 2017, I’ve gained 30 lbs. Recently lost 10 on phentermine. But now I’m gaining again, my TSH is 18 and my Dr is having trouble regulating it. I take 75 synthroid I’ve tried the t3 levothyroxine a few years ago but it didn’t help. I bounce back and forth between high tsh and very low.008 I am exhausted trying to figure it out, and live peacefully. Any advice is welcome.