The Best Dihydroberberine Supplement For Weight Loss

As long as you are getting dihydroberberine in whatever supplement you’re taking, you should get the benefits you’re looking for:

Faster weight loss (1), better blood sugar control (2), lower insulin, appetite suppression (3), and GLP-1 activation (4).

That said, there are definitely some differences between dihydroberberine products, and those differences do matter.

Which is why I’ve broken down the best dihydroberberine supplements for weight loss by potency, affordability, and combination of ingredients:

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#1. Berberine 500+ By Dr. Westin Childs (Most Powerful & Potent)

berberine 500+ glp 1 activator for weight loss energy metabolism dihydroberberine alpha lipoic acid

This formula contains dihydroberberine as the trademarked ingredient GlucoVantage with a therapeutic dose in each serving.

But on top of that, you’ll also get alpha lipoic acid and berberine hcl.

This is great for weight loss because alpha lipoic acid (ALA) synergizes with the effects of dihydroberberine on AMPK and GLP-1 (5), making both ingredients more effective.

And with the inclusion of berberine hcl, you get both immediate and short-term stimulation, making this an SR and IR berberine supplement.

This means each dose stays in your system, stimulating your cells, suppressing your appetite, stimulating muscle growth, and supporting metabolic health throughout the entire day.

Why I Like it:

Physician formulated and designed specifically to help with weight loss (other formulas may lean more towards berberine’s effects on blood sugar).
Each serving provides a therapeutic dose of dihydroberberine (200 mg) as GlucoVantage.
Includes combination ingredients (a racemic mixture of alpha lipoic acid as well as berberine HCL).
60 servings per bottle.
Third-party tested, manufactured in the USA, and non-GMO.

Potential Cons:

Higher cost per bottle with the inclusion of additional ingredients and 60 servings.

If you’re looking for raw power and you want dihydroberberine to help you lose weight, this is your best option.

But if you’re on a budget and you are more price sensitive, then this next one may be better:

#2. Dihydroberberine by Doublewood Supplements (Most Affordable)

dihydroberberine supplement for weight loss

The biggest benefit of this formula is the price, but it does come with one major downside:

Each serving provides a smaller dose of dihydroberberine at 100 mg.

The good news is that it does come as the trademarked ingredient GlucoVantage.

The big problem is that for weight loss, you’ll want a dose of 200-400 mg of dihydroberberine each day.

If you’re using this formula, that means taking between 2-4 capsules.

But if you’re price-sensitive and you’d rather get some dihydroberberine into your system each and every day, then this is probably your best bet.

Just realize that the benefits on your weight will be less compared to other products and formulas.

Why I like it:

More affordable compared to other options.
Third-party tested, non-GMO, and manufactured in the USA.

Potential cons:

The reduced dosing per capsule (100 mg) means you’ll need to double or quadruple how much you take for weight loss.

#3. Dihydroberberine by Toniiq (Most Well-Rounded Combination Berberine Supplement)

dihydroberberine supplement with milk thistle and ceylon cinnamon

This formula includes dihydroberberine at 200 mg per serving (as GlucoVantage) while also providing you with Ceylon cinnamon and milk thistle.

While this is a cost-effective option for getting a lot of great ingredients in each serving, its biggest downside is that it’s not specifically formulated for weight loss.

Here’s what I mean:

Ceylon cinnamon, while extremely beneficial for your body, primarily targets insulin and blood sugar (6), while milk thistle acts on the liver (7).

This formula is great for someone who has a combination of obesity, fatty liver, and insulin resistance, but it will not be the best option for weight loss specifically, and some people may be paying for ingredients that provide little utility to their situation.

All that said, you still can’t go wrong with this formula.

Why I like it:

Includes a therapeutic dose of dihydroberberine.
Includes additional ingredients designed to support liver health and blood sugar.
Good option for people who are price-sensitive.

Potential cons:

There are better formulas for weight loss.

Should You Use Dihydroberberine Or Berberine HCL?

For weight loss, the answer is obvious:

Both.

Dihydroberberine is often touted as the best option because it has much higher bioavailability, but this isn’t everything.

While it’s true that you will absorb more using this form of berberine, this rapid absorption comes with a shorter half-life.

In other words, it doesn’t stay in your system very long.

You can think of dihydroberberine as an immediate release form and berberine hcl as a sustained release form.

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And in a perfect world, you’d want a balanced combination of both to allow your body immediate and long-term benefits.

And it’s for this reason, I recommend using both forms, especially for weight loss.

The biggest downside to this method will be cost, as berberine is not an inexpensive ingredient.

But if you want to give your body the best shot possible at losing weight and keeping it off, this is what you’ll want to do.

But remember:

The best and most effective way to lose weight isn’t to take supplements. It’s to optimize your diet, stay active, and responsibly reduce your calories (with fasting).

The use of dihydroberberine just complements these other treatments.

But if you like the idea of using supplements to help you lose weight faster, check out this article next.