Leptin Resistance Rx - Leptin Sensitizer with ORALVISC & GAGs for Metabolic Support

Leptin Resistance Rx – Leptin Sensitizer with ORALVISC & GAGs for Metabolic Support


  • Helps lower serum leptin levels*.
  • Helps lower inflammation and inflammatory cytokines*.
  • Both animal studies and human studies suggest ORALVISC helps lower serum leptin levels*.
  • Designed to be used as part of a comprehensive weight loss program.

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Leptin Resistance Rx – Targeting Fat Cells & Leptin Resistance

Leptin Resistance Rx is an over the counter supplement which contains a blend of special glycosaminoglycans (GAGs for short) combined with Vitamin C which help target serum leptin levels and inflammatory levels.

The result?

It is one of the very few supplements which have been shown in clinical trials in both humans and animals to help lower serum leptin levels and manage weight.

One Human Trial showed that taking ORALVISC (blend of GAGs found in Leptin Resistance Rx) daily for 12 weeks resulted in reduced serum leptin levels, inflammatory markers, and cytokines.

I find leptin resistance to be one of the most important underlying hormone imbalances in people who are overweight, especially those with thyroid problems and sex hormone imbalances.

Leptin Resistance Rx is designed to be used as part of a comprehensive weight loss program to help boost your metabolism and assist with weight loss.

How it Works

Leptin resistance is prevalent in all obese patients who have an elevated leptin level but who are unable to lose weight.

This combination is sufficient for the diagnosis of leptin resistance.

What you may not realize is that leptin is probably the single most important factor when determining how likely you are to lose weight and keep it off.

The higher your leptin level, the more leptin resistance present in your body, the less likely you are to lose weight.

This is well known and non-controversial.

While we know that this is the case, there haven’t been many great treatments available to patients with this condition.

Leptin Resistance Rx may help fight leptin resistance by helping to lower serum leptin levels (thereby sensitizing your body to leptin), by helping to reduce inflammation (thereby indirectly improving thyroid function), and improving fat cell turnover by influencing genetic markers on fat cells.

How to Use Leptin Resistance Rx – Treating Leptin Resistance

If you have leptin resistance then you know that it is a difficult condition to treat.

I want to be very clear that while this supplement may help lower your leptin levels and improve leptin resistance it should never be used alone for weight loss.

Instead, it should ALWAYS be used as part of a comprehensive weight loss plan that includes both changes to your diet, exercise, and intermittent fasting.

If used in this way then you will see the best results! Leptin Resistance Rx will help lower your leptin levels which makes your body more susceptible to weight loss but it may not directly lead to weight loss unless it is also combined with other therapies.

How to use Leptin Resistance Rx:

  • For light leptin resistance (serum leptin level between 11-19 ng/ml) -> Use 1 capsule per day and combine with Omega Soothe SR x 3 months in combination with exercise/diet/intermittent fasting.
  • For moderate leptin resistance (serum leptin level between 20-29 ng/ml) -> Use 1 capsule per day and combine with Omega Soothe SR + Gut Bomb 350 Billion x 4-6 months in combination with exercise/diet/intermittent fasting.
  • For extreme leptin resistance (serum leptin level 30+ ng/ml) -> Use 1 capsule per day and combine with Omega Soothe SR + Gut Bomb 350 Billion + Functional Fuel ENERGIZE + prescription medications for leptin resistance in combination with exercise/diet/intermittent fasting.

Leptin Resistance Rx should be used for 1-2 months AFTER you hit your target weight loss goal and during your weight loss phase. This will help you get the best results possible and help you keep your weight off.

Can Leptin Resistance Rx still be used if you aren’t exercising or changing your diet?

The answer is yes, and it will still help sensitize your body to leptin, but you should not expect weight loss during this time if you are not also doing other therapies.

Currently, I find that the combination of high dose probiotics, Leptin resistance Rx, and high doses of fish oil can be helpful in treating leptin resistance (see my recommendations above).

Leptin Resistance Rx can also be used after extreme diets such as the hCG diet to help balance leptin. It is not a cure for the damage done during these diets, but it has the potential to help.


1.) Is this the Right Supplement for me?

If you are struggling with weight gain, the inability to lose weight, or just want help losing a couple of extra pounds then this supplement is ideal for you.

Almost every single overweight person has some degree of leptin resistance and when present, leptin resistance limits your ability to lose weight and keep it off.

By improving your leptin level you will help your body lose weight faster and keep it off longer.

You do NOT have to check your leptin level prior to using this supplement. Just being overweight is enough to know that you have some degree of leptin resistance.

Checking your level can help you determine how severe your leptin resistance is and can be useful, however.

2.) How do you take it?

Take 1 capsule per day, with or without food, for 2-6 months (depending on the severity of your leptin resistance).

The more severe your leptin resistance or the more weight that you want to lose you should take Leptin Resistance Rx for longer.

I recommend continuing taking Leptin Resistance Rx after you get to your target weight for at least 1-2 months to ensure that your weight will stay off.

For more severe forms of leptin resistance, you should also consider adding additional supplements (guidelines above).

3.) Can I take this with Thyroid Medication or other Supplements?

Yes! Leptin Resistance Rx can be used with my other supplements (and, in fact, work better this way) and it can be used with all types of thyroid medications.

4.) How long do I need to take it?

The duration of therapy depends on how quickly you lose weight and how severe your leptin resistance is.

In general, it’s a good idea to use Leptin Resistance Rx throughout the duration of your weight loss phase and at least 1-2 months into your maintenance phase.

As long as you are trying to lose weight you should be taking it!

5.) Are there any side effects?

You should not experience negative side effects while using Leptin Resistance Rx.

6.) Does this product have inactive ingredients?

Nope! This product does NOT contain Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

7.) How does shipping work?

All product orders to the United States receive free shipping. We ship out within 1 day of your order (unless you order on the weekend) and it takes approximately 1-3 days to reach the destination depending on how far you live away from Arizona. All supplements are shipped with free shipping via first class mail through USPS but you can upgrade to priority mail if you prefer as well.

We offer international shipping as well! You can calculate the price of shipping at the checkout page (we do not mark up the cost of shipping) and currently we ship to all countries.

You will receive an email notification once your product is “completed and shipped”.

8.) What is your Return/Refund Policy?

All supplements have a 30-day money-back guarantee.

We want you to take a chance to improve your health and use our high-quality supplements. If you don’t love your supplement simply contact us, ship back the supplement and we will happily provide you with a full refund.

You can find more information about our return and refund policy by clicking here.

If you have questions about our products or our return policy please reach out to us via email at [email protected]

9.) Are your supplements regulated for quality?

Yep! All of my supplements are certified as the highest quality and verified with third-party testing and assays to ensure that they contain what we say they do. They are produced in a GMP compliant facility in the United States.

10.) What if I have other questions?

Please reach out to us via email at [email protected] and we will do our best to get back to you within a day or so! You can also call us here: (480) 331-9431

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

**Results may vary.

Questions about our quality standards? Please see this article for more information.

Additional information

Weight 0.25 lbs
Dimensions 2.5 × 2.5 × 5.0 in

Customer Reviews

Based on 225 reviews
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Leptin Resistance Rx – Leptin Sensitizer with ORALVISC & GAGs for Metabolic Support