These weight loss supplements are designed to help you lose weight by targeting the root cause of weight gain. These supplements help balance weight loss hormones and resistance syndromes such as leptin resistance, insulin resistance, and thyroid resistance. Other supplements work by helping to regulate your appetite, assisting in improving a sluggish metabolism, and helping you build muscle mass. Weight loss ingredients include berberine, glucomannan, propolmannon, ORALVISC, caffeine, probiotics, fish oil, and more.